Dalton Cardiovascular Research Center

01/06/2025

08/07/2024

Tzyh-Chang Hwang, PhD Laboratory publishes in Nature

“Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore”

Xiaolong Gao, Han-I Yeh, Zhengrong Yang, Chen Fan, Fan Jiang,
Rebecca J. Howard, Erik Lindahl, John C. Kappes, &
Tzyh-Chang Hwang

Loss-of-function mutations of the CFTR gene cause the
life-shortening genetic disease cystic fibrosis (CF).

Using cryogenic electron microscopy, Gao et al. uncovered how CFTRInh-172 inhibits CFTR function by binding in its pore and allosterically inhibiting its gating. Their findings could pave the way for structure-based drug design for the treatment of secretory diarrhea and polycystic kidney disease.

08/01/2024

David Kline, a professor in Mizzou’s College of Veterinary Medicine and researcher at the Dalton Cardiovascular Research Center study of high blood pressure and its link to sleep apnea:
https://showme.missouri.edu/2024/how-does-the-brain-respond-to-sleep-apnea/?utm_campaign=553184_Show%20Me%20Mizzou%20-%20Tuesday%2C%20July%2030%2C%202024%20%28ALL%29&utm_medium=email&utm_source=The%20Curators%20of%20the%20University%20of%20Missouri&dm_i=7IQU,BUU8,3GWGR2,1S7YB,1

04/17/2024

Congratulations!

Yoko Wang, PhD
receives MU Postdoctoral Research Grant from
the MU Office of Postdoctoral Education

Dr Wang joined Dalton in September of 2023
and is a Biomedical Sciences post doctoral fellow
in the Laboratory of Carie Boychuk, PhD

11/08/2023

Franklin Endowed Lecture

Friday, November 10, 2023
NextGen Atkins Seminar Room
10:00 am

Robert Mecham, PhD

Professor Emeritus, Cell Biology & Physiology
Washington University School of Medicine

"How to build a blood vessel: mechanical and instructive signals from the vascular extracellular matrix."

11/08/2023

31st Annual Cardiovascular Day, March 5, 2024

The James O. Davis Distinguished Lecture in Cardiovascular Science

Mark T. Nelson, Ph.D.
Chair and University Distinguished Professor
Department of Pharmacology
University of Vermont

01/31/2023

Xiaoqin Zou, PhD and Resident Dalton Investigator named 2022 AAAS Fellow

Jan. 31, 2023Contact: Eric Stann, 573-882-3346, StannE@missouri.edu Today, the American Association for the Advancement of Science (AAAS) named five University of Missouri professors as 2022 Fellows for their distinguished efforts in advancing various fields of science. The recipients are: Shubhra G...

01/09/2023

David D. Kline, PhD, Resident Dalton Investigator, Department of Biomedical Sciences receives a 4 year award from NATIONAL HEART, LUNG, AND BLOOD INSTITUTE.

11/15/2022

Rowena Woode, DVM, PhD, Biomedical sciences postdoctoral fellow in the Laboratory of Dalton Resident Investigator, Lane Clarke, DVM, PhD was one of five Students from the University of Missouri to attend the SEC Emerging Scholars Program.

10/21/2022

Liping Zhang, Graduate Student, Medical Pharmacology & Physiology wins
The 8th Mizzou Three Minute Thesis (3MT) Competition.

Liping is a student in the Laboratory of Resident Investigator and Interim Director, Dr Michael A. Hill.

The first place winner, receives a plaque and $500 in professional development funds; as well as represents Mizzou at regional 3MT contest in Chicago, IL in March 2023.

Three Minute Thesis (3MT) is a research communication competition developed by The University of Queensland. Research higher degree (PhD and MPhil) students have three minutes to present a compelling oration on their thesis topic and its significance. 3MT is not an exercise in trivialising or ‘dumbing-down’ research, but challenges students to consolidate their ideas and research discoveries so they can be presented concisely to a non-specialist audience.

Congratulations Liping!