01/14/2025
RAPID, Substance P and Stem Cells… SAY WHAT???
If you know RAPID you know that one of our main goals is to stimulate the release of substance P.
Science is showing increasing support for the role of substance P in mobilizing endogenous mesenchymal stem cells (MSCs) for improved tissue repair and inflammation regulation following bone injuries.
Meaning SP stimulates the body’s own endogenous stem cells to move from their storage sites-such as bone marrow into the bloodstream or to the site of injury or tissue damage.
From the study…
-Substance P promoted the mobilization of endogenous MCS’s.
-In cases of transplanted MSCs the transplanted cells often show survivability issues which hampers the outcome of regeneration.
-Intravenous substance P has been shown to mobilize endogenous MSCs, which is superior to their transplanted counterparts.
-Endogenous MSCs are located in different adult tissues and can move to an injury site when activated.
-MCSs can turn into various cell types, but they also help control inflammation after an injury, which supports tissue repair.
-Recent studies have shown that substance P, which acts as a messenger triggered by injury, can play a role early in the wound healing process by mobilizing MSCs from the bone marrow into the bloodstream.
https://www.nature.com/articles/s41598-018-31414-5
