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https://health.ucdavis.edu/news/headlines/teenaged-daughters-bone-marrow-saves-dads-life/2026/02March 4, 2026Teenage dau...
04/05/2026

https://health.ucdavis.edu/news/headlines/teenaged-daughters-bone-marrow-saves-dads-life/2026/02

March 4, 2026
Teenage daughter’s bone marrow saves dad’s life
By Erin Baily

For Hai Trinh, his disease started gradually. Fatigue. Bruising easily. He thought little of it.

As a mechanic, husband and father of two girls, he just kept pushing forward, attributing the persistent health challenges to his long working hours and physically demanding job.

When Hai finally went to his doctor, he learned he had low blood platelets, also called thrombocytopenia. The condition indicates less than 150,000 platelets per microliter of blood due to the failure of marrow cells to produce platelets. This leads to bruising, pinpoint red spots called petechiae and prolonged bleeding. Hai was also experiencing tiredness and other symptoms.

That was in the early 2010s.

Playing the waiting game
Asian man and young girl in a horse stable where she sits on a saddle while he waves at the camera wearing sunglasses.
Hai Trinh and his youngest daughter, Viana.
Over the next five years, Hai tried several different treatments to improve his condition and either got a partial response, no response or had side effects from the medications.

Then he met Mehrdad Abedi, a UC Davis Health bone marrow transplant doctor who serves as part of the stem cell transplant program team.

“One of my hematologists recommended I go see Dr. Abedi,” Hai said. “He suggested a bone marrow transplant. I told him I was scared of the procedure because I would have to be off work for a few months. That is very inconvenient for me because I work full time, and I am the main income for the family.”

A bone marrow transplant is a procedure that infuses healthy blood-forming stem cells into the body to replace bone marrow that is not producing healthy blood cells. Also called a stem cell transplant, the procedure may use cells from the patient’s own body (autologous transplant) or from a donor (allogeneic transplant).

Despite the promise of potentially curing the disease, Hai decided against the transplant. But his symptoms got worse. He had multiple hospitalizations and weekly clinic appointments. He became more and more anemic, requiring weekly blood transfusions. Hai also had infections from low white blood cell counts. Still, he waited and put up with uncomfortable symptoms for another five years.

Headshot of Asian man in a red shirt, a white undershirt and a grey beanie.
One of my hematologists recommended I go see Dr. Abedi. He suggested a bone marrow transplant. I told him I was scared of the procedure."

Hai Trinh, bone marrow transplant patient
Time was running out
By this time, Hai was miserable. More than a decade of living with this condition had taken a toll. Even worse: A bone marrow biopsy revealed that his bone marrow was almost gone.

“Hai was still very hesitant to have the transplant, but as this disease progressed, he realized his work and life were already complicated by being in the hospital or being in a clinic all the time,” Abedi said. “At this point, he had hypoplastic MDS/severe aplastic anemia and agreed that he just couldn’t continue like this.”

Aplastic anemia is a condition that happens when your bone marrow stops making enough new blood cells. A rare and serious disorder, aplastic anemia can develop at any age. It can happen suddenly or come on slowly and worsen over time like it had for Hai.

Hypoplastic myelodysplastic syndrome (MDS) is a rare form of myelodysplastic syndrome in which the bone marrow has fewer cells than it should. In essence, it represents a “bone marrow failure” subtype of MDS characterized by peripheral cytopenias (low blood counts) and dysplasia (abnormal development or growth of cells, tissues or organs). These two conditions often look similar in blood tests and in the symptoms patients experience and can progress to acute leukemia if left untreated. “He had zero chance of any long-term survival without the transplant,” Abedi said.

Headshot of a dark haired man in with a blue collar and a white doctor's coat.
Hai was still very hesitant to have the transplant. But at this point, he had hypoplastic MDS/severe aplastic anemia and agreed that he just couldn’t continue like this.”

Mehrdad Abedi, bone marrow transplant doctor
With this news, Hai finally agreed to the transplant.

Hai’s best chance of survival
Hai’s next challenge was to find a life-saving donor since he wasn’t producing bone marrow of his own.

The quest for a match was underway.

“Searching for an available, best matched donor who is also agreeable, eligible and suitable to donating bone marrow stem cells — which is the preferred graft source for Mr. Trinh’s diagnosis — can be challenging,” said Grace Chan, UC Davis Health stem cell transplant nurse coordinator. “Especially given his ethnic background as a Vietnamese American.”

Plus, stem cells from non-family members are usually not the ideal option.

“When we have an unrelated donor, that increases risk of transplant related complications,” Abedi said. “We really wanted to explore the idea of having a family member, ideally one of his children.”

UC Davis pediatric stem cell transplant program
Blonde woman and black haired woman both in blue scrubs pose in a hospital hallway.
Kelly Yurkosky, left, and Grace Chan are pediatric and adult bone marrow transplant coordinators at UC Davis Health. The two helped Viana and Hai navigate the bone marrow donation and transplant process.
A donation of pediatric bone marrow (or peripheral blood stem cell) to an adult offers significant survival benefits due to the quality of younger stem cells. These grafts are more robust, often leading to better transplant outcomes, improved long-term survival, reduced graft-versus-host disease (GVHD) and faster immune recovery for the adult recipient.

Although pediatric to adult stem cell donations are not unique, UC Davis — a leading transplant center in California — had just launched its pediatric program. Perfect timing for Hai.

But first, the tests. And then a serious conversation with his children — perhaps one of them could be the right donor.

“My parents never really told us details about dad's health,” said Hai’s youngest daughter, Viana. “He's been sick for so many years, so it was a surprise when they said they needed my sister and me to get tested … like now.”

Hai’s wife and Viana’s mom, Tracy, had mixed emotions about what could come next.

“At the beginning, I was worried for both my daughter and my husband,” Tracy said. “The doctor explained it to us, but I was afraid it would not turn out the way we wanted.”

The best match
Hai’s two daughters, including Emily and 17-year-old Viana, drove to UC Davis Health to get their blood tested. Hai’s medical team was elated with the results: Both daughters were acceptable donors for their dad. The transplant team suggested Viana, who has the same blood type as Hai.

Three photos, left to right: Young girl sits on her father's shoulders, each wearing yellow glasses; same girl with short black hair puts her arm around her dad who is wearing sunglasses; same girl is now a high school graduate in her robe with he dad and mom on each side of her.
Viana and her parents, Hai and Tracy, through the years.
“When we were able to identify Mr. Trinh’s teenage daughter as the best possible donor option, he felt a mix of happiness yet worry about the bone marrow harvest procedure his daughter would endure,” said Chan, the nurse coordinator. “We were able to provide him with the reassurance that his daughter would be under the excellent, experienced care of the Pediatric Stem Cell Transplant Program, which brought forth feelings of relief and ease."

Viana was also nervous about what was to come.

“The idea of going under anesthesia scared me. This would be the first procedure I had ever had,” Viana said. “But I reminded myself that the only thing I really wanted to do was to help my dad.”

Viana consulted with the transplant team and agreed to make what she called a “life-changing” decision for her and her father.

“I didn't think I would ever be able to do anything like that at my age,” she marveled.

Headshot of young Asian woman with black hair wearing a white sweater.
The idea of going under anesthesia scared me. This would be the first procedure I had ever had. But I reminded myself that the only thing I really wanted to do was to help my dad.”

Viana Trinh, bone marrow donor
But the team at UC Davis was ready to help make that happen.

“Through close collaboration between the adult and newly established pediatric team, our program was able to offer Mr. Trinh the best possible opportunity for a curative outcome,” said Kelly Yurkosky, pediatric bone marrow transplant coordinator. “To me, the Trinh family embodies the vision of our integrated adult and pediatric stem cell transplant program at UC Davis: to serve the greater Sacramento region by providing access to the stem cell transplant and cellular therapy treatments our patients need.”

Transplant pending
By now it was the Fall of 2025. As the transplant date drew near, the family learned that the preparation would take longer than they wanted because the medical team recommended Hai undergo a round of chemotherapy.

Hai was getting anxious.

“We did all the tests and the consultations. It was a little scary when I talked to the chemo doctor because it may be harmful. But they told me I must do it because they wanted to get rid of the bone marrow by cleaning up inside my body before they put the new cells in.”

However, the delay was problematic for the family because Viana was soon leaving for her freshman year of college.

“I was worried about Viana. I knew she would need time to recover, and I wanted to be beside her so I could take care of her, too,” said Tracy. “But that wasn’t going to happen.”

In the meantime, Hai counted down to the procedure: “Minus 9 days, minus 8, minus 7,” Hai recalled. “And then zero days and it was time for the transplant.”

Dad and daughter undergo dual procedures
Everything went well with part one of the process: Viana’s bone marrow donation. It involves general anesthesia and inserting a needle to extract bone marrow from two spots on the back of the pelvis.

Young Asian woman in a surgical mask and hospital gown stands next to an Asian man in a hospital gown after they both had a procedure in the hospital.
Viana and her dad, Hai, reunite after she had her procedure to donate bone marrow to him.
Viana was surprised by how easy it was and how good she felt. She couldn’t wait to see her dad.

“Once I was able to get up, I waddled over to my dad's floor. My stem cells were already getting transfused into him,” Viana said. “I cried. It was very emotional for me.”

Within a week of her procedure, Viana and her mom were scheduled to drive to San Jose.

“She rested for five days and then I moved her down there,” Tracy said. “Hai was still in the hospital. It was heart wrenching for us.”

Viana struggled over the next month or so, but not from the procedure. She missed her family and was worried about her dad.

“My lower back was sore for a week or two, but I was still able to walk. It was manageable,” Viana said. “But I was away from home for the first time and was missing my parents.”

Hai continued to recover at UC Davis Medical Center and provided updates to Viana during video chats.

Three photo compilation: From left to right - Asian man in a hospital gown and a knit beanie sits on a hospital bed; same Asian man faces the camera making a heart shape with his hands as he stands next to a dark haired man on his left who is wearing a surgical mask and stethoscope; the same two men look at one another as the Asian man sits on a hospital bed while the doctor stands beside him.
Hai spent several weeks in the hospital recovering from his bone marrow transplant. His doctor, Mehrdad Abedi, visited him to check on this progress.
“I remember this one day during my first few weeks at school. My mom FaceTimed me from the hospital and my dad had a beanie on,” Viana said. “When he took the beanie off, he was bald, and I just started crying. It was hard to see him like that. But he had a smile on his face and looked happy. It was bittersweet.”

New stem cells, new life
The happiness and smiles continue.

“I'm feeling OK now,” Hai said a few months after the transplant. “Much better than before. I don't get bruising. I don't get bleeding. It’s very good news.”

According to Abedi, Hai has a 70-80% chance of being cured of the disease. Viana is hopeful.

Four people in photo: From left to right, young Asian woman with shoulder length black hair, another young Asian woman with longer highlighted black hair; another Asian woman with shorter brown hair; and an Asian man with a purple short and tan blazer.
Hai spends time with his family, from left to right: daughters, Emily and Viana, and his wife, Tracy.
“I want him to be satisfied in his life and don't want this disease to have any more effect than it already has,” Viana said. “With what we both went through, I just hope for him to have a full recovery.”

That remains to be seen, but Hai knows one thing for sure.

“I am forever grateful. For my daughters, my wife, the UC Davis Health staff,” he said. “It was a miracle.”

Don’t wait
With this new lease on life, Hai also has a new perspective about delaying care.

“I wanted to fix it, but thought it would be horrible for me,” Hai said. “But, you know, I was lucky because the doctors, staff, nurses, even the janitors were great people. They treated me like family. I felt very comfortable during my stay in the hospital.”

Hai wants others to not fear the procedure.

“I would say to anybody who is in the same situation as me, make the decision to get the bone marrow transplant at UC Davis,” Hai said. “Don’t wait.”

From the time he was in the hospital until after he arrived home, Hai made the heart sign as a tribute to his new lease on life.
Viana had equally encouraging words for anyone considering becoming a donor.

“I think it really needs to be emphasized that it's a really safe procedure,” Viana said. “I don't think anyone should be scared about donating their stem cells or bone marrow because it could save a person's life.”

Especially when that person is your father.

Viana’s heroic role and her dad’s recovery have altered her career plans.

“I already wanted to go into nursing, but now I am pursuing pediatric nursing because of my family’s time at UC Davis,” Viana said. “Our experience makes me hopeful for the future of medicine.”

After years of fearing and delaying treatment for a blood disease, Hai Trinh finally got a bone marrow transplant — from his 17-year-old child.

04/05/2026
https://news.med.miami.edu/sylvester-myeloma-institute-advances-multiple-myeloma-care/Sylvester Comprehensive Cancer Cen...
04/04/2026

https://news.med.miami.edu/sylvester-myeloma-institute-advances-multiple-myeloma-care/

Sylvester Comprehensive Cancer Center Researchers Highlight Progress in Myeloma Treatment
By: Tara Roberts | March 23, 2026 | 9 min. read | Share
At a Sylvester Myeloma Institute luncheon, University of Miami Miller School of Medicine physicians shared advances in clinical trials, precision medicine and efforts to accelerate a cure for multiple myeloma.

Rafat Abonour, M.D., recently joined Sylvester Myeloma Institute at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. During an informational luncheon for patients and donors on Feb. 26, the hematologist/oncologist had the opportunity to share the two things that excite him most about his work: caring for his patients and being part of the University of Miami.

“If there is any team in this country that is ready to say, ‘We are going to cure multiple myeloma,’ I am convinced it’s the Sylvester team,” said Dr. Abonour, a professor in the Divison of Myeloma at the Miller School.

Building a National Leader in Multiple Myeloma Research and Care
Dr. Abonour was drawn to Sylvester by the work of C. Ola Landgren, M.D., Ph.D., director of the Sylvester Myeloma Institute and professor and chief of the Miller School’s Division of Myeloma. The world-renowned myeloma expert helped to establish the institute in 2022. His goal at that time was to make Sylvester’s myeloma program one of the top three in the nation in its first five years.

Dr. Landgren was recruited to Sylvester in 2020 by Stephen D. Nimer, M.D., director of Sylvester, the Oscar de La Renta Endowed Chair in Cancer Research, executive dean for research and professor of medicine, biochemistry and molecular biology at the Miller School.

Physicians, left to right:
Rafat Abonour, M.D., Brian Walker, Ph.D., Gil Hevroni, M.D., Benjamin Diamond, M.D., Abhishek Pandey, M.D., C. Ola Landgren, M.D., Ph.D.
From left, Dr. Rafat Abonour, Dr. Brian Walker, Dr. Gil Hevroni, Dr. Benjamin Diamond, Dr. Abhishek Pandey and Dr. C. Ola Landgren
“Multiple myeloma is a disease where great progress has been made,” said Dr. Nimer. “It was essential to bring that progress to South Florida and build a comprehensive and outstanding myeloma program.”

Myeloma is a blood cancer that causes uncontrolled growth of white blood cells called plasma cells. The cancerous cells can crowd out healthy cells in the bone marrow and lead to bone damage, infections and other problems. The American Cancer Society estimates that about 36,000 new cases of myeloma will be diagnosed in the United States in 2026. Prognosis is getting better and patients live longer and longer, but there is not yet a cure for the disease. Currently, more than 200,000 Americans live with multiple myeloma.

Accelerating Treatment Through Clinical Trials and Precision Medicine
To meet that need, the Sylvester Myeloma Institute grew rapidly. Its team of 70 physician-researchers, clinicians and support staff currently have 29 open clinical trials, with an additional 10 in the pipeline, meaning patients are being treated with the newest drugs and technologies.

“I think we have already delivered one of the top three programs in myeloma,” Dr. Landgren said. “We are here to win the Stanley Cup of myeloma research and clinical care. We do not want anyone to have myeloma. But if anyone has myeloma, we want to be the ones to go to for help.”

The institute’s work combines laboratory research, clinical trials, patient care and using samples from patients to inform research.

“That is how you can accelerate the science and deliver treatment quickly to patients,” Dr. Landgren said.

Promising Projects for Myeloma Patients
Sylvester Myeloma Institute member Benjamin Diamond, M.D., highlighted the genomics-based prediction model he developed, which helps clinicians understand how changes in each patient’s myeloma might affect their outcomes and responsiveness to treatment.

“With all of the data that we have, we want to be able to understand everybody’s unique situation, because every disease is unique,” said Dr. Diamond, an assistant professor in the Miller School’s Division of Myeloma. “There truly are multiple myelomas, and so we don’t want to treat every patient the exact same way.”

One experience myeloma patients have in common is bone marrow biopsies to assess how the disease is responding to treatment.

Sylvester Myeloma Institute member Gil Hevroni, M.D., discussed a new clinical trial to test a port implanted in the bone, similar to a chemo port, which would make taking samples easier. This project fits into Dr. Hevroni’s goal of helping myeloma patients improve their quality of life.

“I know that even with patients who have no detectable disease, there are still things we have to work on in terms of side effects,” said Dr. Hevroni, an assistant professor in the Miller School’s Division of Myeloma. “So, I’m here to listen and to hear what they are dealing with.”

Using Minimal Residual Disease Testing to Speed Drug Development
Another important technique for checking response to treatment is minimal residual disease testing, or MRD, which measures cancer biomarkers and was pioneered by Dr. Landgren.

At Sylvester, clinicians use MRD to personalize treatment. For example, Dr. Landgren said, they might step down the intensity of therapy for a patient with no detectable disease.

MRD is also valuable for developing new drugs, he said. Dr. Landgren’s research showed that testing clinical trial participants for biomarkers can dramatically shorten the time it takes to get results.

Based on Dr. Landgren’s work, the FDA recently released guidance for myeloma drug trials that supports using this technique. This means that new drugs can be approved within a few years, instead of waiting 10 or 15 years. Patients can get access to new therapies much faster, and many lives can be saved based on this important work on MRD as an early endpoint for drug approval in multiple myeloma.

“We expect that the whole drug development field for myeloma, which is going very fast, is going to go even faster,” Dr. Landgren said. “I am proud and happy that patients are getting access to new and better drugs much faster based on these efforts. Going forward, I think this will be one of the important pieces to develop a cure.”

Trials for Diet and Precursor Conditions
Other Sylvester Myeloma Institute researchers joined the panelists to share research that goes beyond diagnosis and treatment.

Abhi Pandey, M.D., an assistant professor in the Miller School’s Division of Myeloma, answered a common patient question: What should people who have myeloma or myeloma precursors eat?

Food and diet influence health, Dr. Pandey said, but researchers are actively studying exactly how different foods or eating schedules could influence myeloma, and whether diet could make treatment work better with fewer side effects. His team is launching a clinical trial in May to study diet, fasting and other interventions for myeloma patients.

David Coffey, M.D., explained his research to better understand which patients with myeloma precursor conditions are at the highest risk of developing multiple myeloma. Dr. Coffey, an assistant professor in the Miller School Division of Myeloma, encouraged people with smoldering myeloma to find out if they are eligible for Dr. Landgren’s clinical trial to study an early intervention treatment.

“We presented at the American Society of Hematology (ASH) meeting, the largest world meeting for blood diseases, in December last year our first results from this study, and in 100% of the patients we have treated, we cannot find any disease after six or eight months of therapy, which is remarkable,” Dr. Landgren said.

For more information on how to support the Sylvester Myeloma Institute, email Britten King.

Experts at the Sylvester Myeloma Institute shared advances in multiple myeloma clinical trials, personalized treatment and drug development.

A couple days ago, we unfortunately missed Doctor Appreciation Day.  Better late than never:)  Here is a poem of gratitu...
04/02/2026

A couple days ago, we unfortunately missed Doctor Appreciation Day. Better late than never:) Here is a poem of gratitude for those wonderful doctors.

Where Life Begins Again

In quiet halls where courage hums,
Where fear and hope together come,
You stand with steady, practiced hands—
Guardians at life’s fragile edge.

You read the stories in our blood,
In numbers, cells, in rising floods
Of questions we don’t know to ask,
Yet trust you deeply with the task.

You carry more than charts and scans—
You hold our futures in your plans,
Our children’s names, our whispered prayers,
The weight of all our silent cares.

Through long, uncertain, fragile nights,
You walk with us through hardest fights,
Explaining storms we cannot see,
And anchoring possibility.

You celebrate the smallest wins—
A count that climbs, new strength within,
A moment where the body turns
From barely holding… back to living.

You do not just extend our days,
You give them meaning, give them grace—
More birthdays, laughter, time restored,
The ordinary we once ignored.

And though the world may never know
The depth of all the seeds you sow,
We carry forward what you’ve done—
In every breath, in every sun.

So here’s our quiet, endless thanks
For every risk, for all the chances,
For standing where few ever could—
And choosing, daily, to do good.

You don’t just treat—
You change the story.

04/01/2026
To register, go to https://pburkhard.wufoo.com/forms/z1gftgny1esam0u/This month’s call-in Lunch & Learn program will foc...
04/01/2026

To register, go to https://pburkhard.wufoo.com/forms/z1gftgny1esam0u/

This month’s call-in Lunch & Learn program will focus on lab results post-transplant. Phyllis McKiernan, APN, MSN, OCN, Advanced Practice Nurse in the Blood and Marrow Stem Division at the John Theurer Cancer Center will cover why these tests are so important to survivorship, including how these results help to track progress posttransplant, and guide adjustments to necessary medications. Phyllis will educate us regarding the importance of monitoring chimerism studies, viral reactivation, vital organ function and much more. As well, Mendya Griffith, a survivor of acute myeloid leukemia (AML) from Augusta, Georgia will share her story and experience in understanding lab results and more. Jennifer Gillette, LMSW on staff, will host the program. There will be time for questions as well.

If you have any technical issues related to registering, please email peggyburkhard@nbmtlink.org or call (248) 770-5172. The call-in information is contained in the form you use to register.

Note: You call in to participate. (We do not call you.)

This FREE program is intended to provide psychosocial and emotional support along with health information from national experts regarding critical topics surrounding cancer and treatments.

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