Open Wound Research

11/03/2025

🚨 New Publication Alert 🚨

We are excited to share that our paper:

“A Bayesian hierarchical meta-analysis of CAMPs versus standard of care for diabetic foot ulcers: Systematic review of evidence from Medicare’s 2024 final Local Coverage Determinations” https://lnkd.in/eWYzPiR2
(Authors: Zwelithini Tunyiswa, Dr. Robert Frykberg and Ryan P. Dirks)

has been published in the inaugural issue of the International International Journal of Tissue Repair.

🔍 Key insights
- Bayesian hierarchical beta-binomial model applied to randomized clinical trials cited in Medicare’s 2024 LCDs
- Standardized outcomes to 12-weeks and n = 100 (50/arm) for comparability
- Findings suggest that CAMPs may roughly double healing likelihood vs standard of care in diabetic foot ulcers
- Estimates are product- and study-adjusted, providing a quantitative benchmark for clinicians, payers, and innovators

💡 Why this matters
Diabetic foot ulcers remain one of the most costly, high-morbidity chronic complications of diabetes. Strengthening the quantitative foundation around advanced wound therapies is essential for evidence-based care, payer policy, and innovation.

👥 With gratitude
Thanks to the International Journal of Tissue Repair editorial team and reviewers for supporting rigorous, transparent wound-care research.

🙏 Open-Access Support
A special thank you to BioStem Technologies (OTC: BSEM) for supporting open-access fees to ensure this work is freely available to the wound-care community. Open access accelerates scientific equity and advances patient care — we are grateful for the partnership.

🔗 Full article
https://lnkd.in/eWYzPiR2

📂 Code & supplementary materials
To promote reproducibility and transparency, the full analysis code and data will be released on the Open Wound Research GitHub shortly.

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01/15/2025

Open Wound Research is proud to participate in Journal of Wound Care (JWC)'s CAMPS 2025 Wound Care Summit. Our CEO, Zwelithini Tunyiswa will be participating on a panel regarding "Optimal trial design for demonstrating evidence on product safety, effectiveness and positive clinical outcomes" with wound care leaders.

12/20/2024

Go check out our latest Podcast episode with Mitch Sanders, PhD. In this episode, we sit down with Dr. Mitch Sanders, a pioneer in wound care and biotechnology. From his extensive academic background in cell biology and biochemistry to leading roles in groundbreaking organizations like WoundForce and Resolys Bio, Dr. Sanders shares his journey through science, entrepreneurship, and innovation. Tune in to explore the intersection of science, creativity, and impact!

🎧Full Episode: https://player.captivate.fm/episode/38fc5010-4c52-4618-a6cd-6580a915c72f/

🎥Full Video: https://youtu.be/XkXQ3m-XT1

11/27/2024

🚨 New Podcast Episode Alert!

Join us for an insightful conversation on the Open Wound Research Podcast, featuring a remarkable journey from podiatry to wound care, entrepreneurship, and advocacy. Learn how our guest, Desmond Bell DPM, CWS, combines clinical expertise with innovation to tackle diabetic foot ulcers, PAD, and calciphylaxis.
Discover the story behind Omeza and the impactful mission of the Save a Leg, Save a Life Foundation, inspiring better outcomes in patient care.

🎙️ Tune in now: https://player.captivate.fm/episode/15b18ae0-36aa-44d4-a55a-be57d32b4031/
Full Video: https://youtu.be/5uknhbDa3g4

11/04/2024

Congrats to Zwelithini Tunyiswa, Dr. Robert Frykberg, Ryan P. Dirks and the team from Open Wound Research on winning second place in the poster competition at Desert Foot. The poster leveraged Bayesian techniques and OWR's extensive pressure ulcer data set to compare patients treated with ProgenaMatrix human keratin matrix to a matched cohort of patients treated with standard of care. Complex pressure ulcers treated with ProgenaMatrix were 2.8 times more likely to heal. Thanks to the conference organizers and judges for this recognition.

10/30/2024

🌵D E S E R T 🦶F O O T🌵

Join Ryan P. Dirks MS, PA,CWS as he presents tomorrow, 10/31/24 at 7:30 on “Pressure
Ulcers- Always the Clear and Present Danger” using data findings from Open Wound Research.

10/11/2024

We’re excited to share that PAWSIC has partnered with Open Wound Research (OWR) to advance transparency and evidence-based care in wound care! 🎉

This collaboration opens new opportunities for cutting-edge research, data access, and advocacy—all aimed at improving patient outcomes and enhancing clinical excellence.

Read the full press release here: https://pawsic.org/pawsic-owr-press-release

10/10/2024

Were you able to catch Ryan P. Dirks & Zwelithini Tunyiswa’s talk at the Symposium on Advanced Wound Care (SAWC) Fall Conference? They spoke on “Treating Hard-to-Heal Wounds with Advanced Products: Perspectives from the Hospital Outpatient and Post-Acute Settings”. Please share some of your favorite highlights!

10/07/2024

Open Wound Research & United Wound Healing United Wound are honored to have our research included the 2024 Symposium on Advanced Wound Care (SAWC) Conference! In case you missed it, here are the posters presented.

09/19/2024

In this episode of "Pathological Heterodoxies in Wound Care," we dive into the fascinating career of Dr. Myles Yu, a pathologist with a unique perspective on wound care. We discuss his origin story in wound care, how pathology fits into the field, and explore how his extensive cancer research background intersects with wound care innovation. Dr. Yu shares insights from his published work and current research, focusing on the pathology of pressure ulcers and how misconceptions in wound diagnosis can lead to treatment challenges.
Check out the full episode:

https://youtu.be/lIrdH6i0V2o

https://player.captivate.fm/episode/014eee04-c8c2-44d8-9e6e-499eefc0ad9e/

09/04/2024

Check out our recent podcast episode

Proudly sponsored by Open Wound Research, https://www.openwoundresearch.com/ In this episode, we delve into the evolving landscape of post-acute wound care, ...

08/26/2024

We are excited to announce the launch of, WoundStats a community forum for Wound Care researchers and quants!

WoundStats intends to help wound care researchers (clinicians/biologists/chemists, etc.), wound care quantitative types (statisticians/modelers/machine learning specialists/AI), and others interested in developing knowledge around wound care to connect, share, and collaborate.

Visit the site, sign-up, and post a question, observation, thought, etc. The team at Open Wound Research will be posting starting this week, and we look forward to developing wound care science and knowledge together.