Sarcoma Foundation of America, Inc.

11/07/2025

In this new report from the Children's Oncology Group, researchers identified molecular features of localized Ewing sarcoma (EWS) that were associated with relapse. In this study, patients with STAG2 mutations were at a higher risk of relapse than other patients. This work may help physicians more effectively strategize treatment for patients at high risk of relapse.

This is a prospective validation of the molecular prognostic features of patients with localized EWS receiving standard-of-care therapy on therapeutic clinical trials. Building on previous work, patients with STAG2 mutations were at high risk of relapse.

11/06/2025

In case you missed “Understanding ctDNA in Sarcomas: Live with the Experts,” the recording is now available! Hear from Dr. David Schulman, Dr. Herbert Loong, and Dr. Edwin Choy as they discuss what ctDNA is and how this emerging science could shape the future of research and care.

Find the recording here: https://www.youtube.com/watch?v=KwMsm53UXrM

11/03/2025

A huge thank you to Meteorologist Jason Adams for MCing our Tampa Race to Cure Sarcoma and Tampa Bay 28 - WFTS for sharing our mission this past weekend and helping raise awareness for sarcoma.

11/03/2025

November is National Family Caregivers Month! If you’re a caregiver/care partner, or if you’d like to thank someone who has cared for you or your loved one, we’d love to hear from you. Email us at communications@curesarcoma.org to share your story so we can highlight it this month.

SFA honors the family members, friends, and loved ones who care for someone with sarcoma. Their love and dedication mean so much to those they support.

10/31/2025

Emma Mayer is currently undergoing treatment for Undifferentiated Pleomorphic Sarcoma. Despite the challenges of her diagnosis, she continues to show incredible strength and courage, raising awareness and hope by joining us at RTCS Los Angeles.

Thank you, Emma, for your strength and for helping SFA raise awareness for .

10/30/2025

Next week, our 2026 Research Grant application is closing. Submit your Letter of Intent by November 6 to be considered.

SFA encourages applications in ALL areas of sarcoma research from both U.S. and international applicants. Researchers are invited to submit LOIs for proposals in pre-clinical, translational, and clinical research on the etiology, molecular biology, pathogenesis, diagnosis, and treatment of human sarcomas.

Learn more about eligibility, funding details, and the review and selection process on our website at https://curesarcoma.org/research/funding-opportunities/sfa-research-grants/

10/28/2025

Recent research shows that pediatric patients with superficial CIC-DUX4 sarcomas may experience better outcomes than those with deep-seated tumors or adult cases. More research is needed to understand what drives these differences and improve care for children with rare .

https://pubmed.ncbi.nlm.nih.gov/41053525/

Soft tissue sarcomas account for approximately 10% of all cancers in the pediatric population, with undifferentiated round cell sarcomas-historically referred to as Ewing-like sarcomas-forming a notable subset. Recent molecular profiling has reclassified these tumors into distinct subtypes, includin...

10/28/2025

Less than one week until our next Live with the Experts! Join us Monday, November 3, at 9:00 AM ET for an expert-led discussion on circulating tumor DNA (ctDNA) in sarcomas.

Submit your questions in advance or use the Q&A feature during the event. You can also share questions anytime using .

Register now: https://tr.ee/rWyatv

10/23/2025

Natasha’s warmth, humor, and courage inspired everyone she met, both in person and through the online community she built to support others facing cancer.

A proud advocate and founding member of SFA’s AYA Committee, Natasha used her voice to raise awareness for synovial sarcoma and empower others to do the same.

In honor of her life and legacy, please consider contributing to Natasha’s Research Fund to advance sarcoma research and continue the impact she began.

https://curesarcoma.org/ways-to-help/donate/donor-campaign/?campaign=possiblynatasha

10/21/2025

SFA is going global! We’re expanding our reach to connect with sarcoma patients, researchers, and advocates around the world. Follow our new global social channels as we share stories, research updates, and advocacy efforts that unite the international sarcoma community.
Together, we can raise awareness, advance research, and work toward a world free from .



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10/20/2025

Over the past 25 years, SFA has worked hard to raise awareness about sarcoma and improve outcomes for patients. Thanks to generous supporters, SFA has invested over $27 million in research, funding more than 240 projects at leading cancer centers. These investments have advanced discoveries in treatment, improved patient care, and brought us closer to finding a cure for .

You can help SFA continue to fund lifesaving research at https://curesarcoma.org

10/16/2025

On Saturday, October 25, 2025, the Massachusetts General Cancer Center is hosting the Sarcoma Innovations Forum, open to anyone interested. Hear from renowned medical professionals in the sarcoma space about cutting-edge diagnostics and treatments, as well as comprehensive support for patients and families.

RSVP by scanning the QR code today!