02/18/2026
You can walk out of your doctor's office with a clean bill of health and still be years into the process of developing heart disease. Nobody tells you this. In my last post I talked about the 45% of women over 20 who are living with cardiovascular disease and don't know it, and I told you exactly what tests to ask for at your next appointment. Today I'm going to show you why those tests matter.
Here's what's happening right now in doctors' offices across the country.
Your doctor orders a basic lipid panel. Total cholesterol, LDL, HDL, triglycerides. The results come back and everything looks fine. Maybe your LDL is a little high, but nothing alarming. You're told to watch your diet and come back in a year.
Your doctor isn't doing anything wrong. She's following the current standard of care. The problem is that the standard of care isn't enough.
A basic lipid panel only shows you part of the picture. It doesn't tell you how many atherogenic particles are actually in your blood. It doesn't measure inflammation. It doesn't show you whether plaque is already forming. It doesn't catch insulin resistance in its early stages.
An advanced lipid panel plus the right cardiac and metabolic markers tells you what's actually happening. And most of the time, those tests are never ordered unless you ask.
𩺠Here are the tests that you need and how they should be interpreted for the most proactive approach to your heart health:
â¤ď¸ ApoB (Apolipoprotein B)
Your doctor looks at your lipid panel and says your LDL is 120. Borderline, but fine. What she doesn't tell you is that two women with an LDL of 120 can have completely different risks depending on how many LDL particles they actually have.
Standard LDL measures the weight of the cholesterol in your blood. ApoB counts the particles. It's the difference between knowing the total weight of cars on the highway versus knowing how many cars are actually on the road. More particles means more opportunity for plaque to form, even when your LDL looks normal.
I have seen women with "normal" LDL and an ApoB over 120. That is high risk. And they had no idea because nobody tested for it.
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Optimal goal: under 90 mg/dL for most women, under 70 mg/dL if you're focused on long-term cardiovascular protection.
â¤ď¸ Lp(a) (Lipoprotein little a)
This one is genetically driven. It has nothing to do with your diet, your exercise, or how clean you eat. If your Lp(a) is elevated, you have a significantly higher risk of early heart attack or stroke regardless of how healthy your lifestyle is.
The frustrating part is that there is no medication that effectively lowers it. The important part is that knowing your Lp(a) changes how aggressively you need to manage every other risk factor. If your Lp(a) is high, your LDL needs to be lower. Your blood pressure needs to be tighter. Your inflammation needs to be controlled.
What does that look like in practice? It means your LDL goal drops from 100 to 70 or lower. It means you treat even borderline high blood pressure instead of waiting to see if it gets worse. It means you prioritize anti-inflammatory strategies like regular exercise, omega-3s, and eliminating processed foods. Lp(a) may be genetic, but how you manage everything else around it is entirely within your control.
You only need to test this once in your lifetime. Most women have never had it checked.
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Optimal goal: under 30 mg/dL or under 75 nmol/L.
â¤ď¸ Coronary Artery Calcium (CAC) Score
This is not a blood test. It's a 10-minute CT scan that shows the actual calcium deposits in your arteries right now. A score of zero in a woman with borderline cholesterol is reassuring. A score of 200 in a woman whose routine labs looked fine changes everything. I covered this in detail in my last post, but it's worth mentioning here because it's the only test that moves you from estimating risk to actually seeing what's happening in your body.
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Optimal goal: zero is ideal, but the score needs to be interpreted in the context of your age and other risk factors.
â¤ď¸ Highly Sensitive CRP (hs-CRP)
Cardiovascular disease is an inflammatory process. Your arteries do not just clog up like a sink. They get damaged, inflamed, and then plaque forms in response to that inflammation. hs-CRP measures the level of systemic inflammation in your body.
If your hs-CRP is elevated, something is driving chronic inflammation and your cardiovascular risk goes up significantly. It does not show up on a standard lipid panel. Most women have never had it checked.
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Optimal goal: under 1.0 mg/L
â¤ď¸ Homocysteine
Elevated homocysteine damages the lining of your blood vessels and accelerates plaque formation. It is an independent cardiovascular risk marker that almost never shows up on routine panels.
The good news is that it is often correctable with targeted B6, B12, and folate supplementation. But you cannot fix what you do not measure.
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Optimal goal: under 10 umol/L.
These are the markers that show you what is already happening in your arteries and what is driving the inflammation and damage that leads to plaque. Tomorrow I'll walk you through the metabolic markers your standard panel is missing, the ones that catch insulin resistance, thyroid dysfunction, and deficiencies years before they become crises.
đ Bring this to your next appointment. If your doctor says these tests aren't necessary, ask why. A good physician will explain their reasoning and help you understand your individual risk. If the conversation feels dismissive or you're not getting the answers you need, it's okay to seek a second opinion or find a provider who practices the kind of preventive medicine you're looking for.
You deserve a partner in your health, not a gatekeeper.