01/05/2026
Timing may be everything for patients with narcolepsy taking Modafinil. Per a study published in PLOS Computational Biology, a mathematical model shows that taking a dopamine reuptake inhibitor, such as modafinil, a few hours prior to the body’s own natural rise in dopamine can extend the effect of the medication. Chronotherapeutics (optimizing medication efficacy with respect to circadian timing) may provide valuable insights related to drug dosage and timing and help facilitate the most effective treatment plan for patients with narcolepsy, Parkinson’s disease, ADHD, depression or even addiction.
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