EpiCypher Inc.

01/22/2026

The Fragile Nucleosome webinar series is back—and EpiCypher’s own Dr. Michael-Christopher Keogh is helping kick it off! 🧬 Tune in Jan 28 for the first session of 2026 featuring Michael, along with Dr. Ho Yu Alan Au. This is a must-attend for chromatin biology fans.
📅 Register for the series now: https://us06web.zoom.us/webinar/register/WN_i4n53UTdQLO8okWVfykxJQ

01/22/2026

How can you profile chromatin accessibility, DNA methylation, and protein footprints in a single assay?

💡 In our Fiber-seq 101 blog, we break down how this long-read sequencing platform is transforming epigenomics. Learn how Fiber-seq goes beyond ATAC-seq and other traditional methods to deliver multiple layers of genetic and epigenetic insights at remarkable resolution.

🔗 Read more: https://www.epicypher.com/resources/blog/fiber-seq-101/

Fiber-seq is a powerful new long-read sequencing assay to simultaneously study genetic and epigenetic features. Read more!

01/21/2026

Having trouble with your CUT&RUN or Fiber-seq experiment? 😅 Don’t stress, the EpiCypher Tech Support Center has the answers.

Explore how-to guides on everything from antibody selection to calculating nuclei inputs. You can also get help with CUTANA™ Cloud data analysis, all in one place.

💻 Visit: support.epicypher.com

01/20/2026

Researchers in genomics, epigenetics, and single-cell biology — expand your toolkit. 👨‍🔬 Join our webinar with Epigenome Technologies, INC to explore how Paired-Damage-seq integrates DNA damage mapping with transcriptomics to reveal cell-type-specific genome instability.

📅 Thursday, January 29 | 1:00 PM EST
🎤 Guest Speakers: Christopher Hartl, PhD (Epigenome Technologies) & Chenxu Zhu, PhD (Weill Cornell Medicine)

Register Today! 👉 https://app.livestorm.co/epicypher/single-cell-dna-damage-analysis-reveals-selective-genome-vulnerability

01/16/2026

CUTANA™ Cloud: CUT&RUN and CUT&Tag analysis — no coding required!

CUT&RUN and CUT&Tag have transformed genomic mapping, but many researchers still face a bottleneck at the analysis stage. CUTANA™ Cloud makes bioinformatics simple, fast, and accessible, taking you from raw data to insights in just a few clicks.

☁️ Get started: https://www.epicypher.com/CUTANA-Cloud

01/15/2026

Congratulations to the 2025 PacBio Epigenetics SMRT Grant awardees. 🧬🎊

We are excited to see these researchers apply long-read epigenomics to fundamental and translational questions across biology. These projects highlight how Fiber-seq can push research forward by capturing chromatin accessibility, DNA methylation, and genetic variation together on single DNA molecules. At EpiCypher, we are proud to provide the products and services that make this level of integrated epigenomic analysis possible.

We look forward to seeing what these labs discover. 🔬🧪 https://www.pacb.com/blog/2025-epigenetics-smrt-grant-awardees/

Learn more about Fiber-seq and how to apply it to your own research here: https://www.epicypher.com/products/fiber-seq/

01/14/2026

That’s a wrap on PAG 33 🎉✅

Thank you to everyone who visited booth 329 this week 🧬 Our booth stayed busy 🔥 and we appreciated every conversation about Fiber-seq and what’s next for epigenome mapping 🔬

We also loved connecting during the poster sessions, including those who stopped by Keith and Hannah’s posters. If we did not get a chance to chat, send us a message and we’ll follow up. Safe travels home ✈️

01/13/2026

Researchers in genomics, epigenetics, and single-cell biology — expand your toolkit. 👨‍🔬 Join our webinar with Epigenome Technologies to explore how Paired-Damage-seq integrates DNA damage mapping with transcriptomics to reveal cell-type-specific genome instability.

📅 Thursday, January 29 | 1:00 PM EST
🎤 Guest Speakers: Christopher Hartl, PhD (Epigenome Technologies) & Chenxu Zhu, PhD (Weill Cornell Medicine)

Register Today! 👉 https://app.livestorm.co/epicypher/single-cell-dna-damage-analysis-reveals-selective-genome-vulnerability

01/13/2026

PAG 33 poster sessions were a big win today. Thank you to everyone who stopped by to ask questions and share ideas! 🧬

We are featuring two EpiCypher presenters: Keith Maier, PhD, presenting “Fiber-seq links sequence, DNA methylation, and chromatin accessibility on single DNA molecules to resolve cis-regulatory grammar,” and Hannah Devens, PhD, presenting “Advancing Agricultural Epigenetics with Direct Multiomic Mapping of DNA Methylation and Chromatin Features.”

🔗 In case you missed it, download the posters here:
• Keith: https://explore.epicypher.com/posters/LRS-keith/pag2025
• Hannah: https://explore.epicypher.com/posters/DNAme/pag2025

01/12/2026

📣 Technology of the Month!

Trends in Plant Science has just highlighted Fiber-seq as its Technology of the Month!
Fiber-seq is a single-molecule, long-read sequencing–based approach that encodes chromatin architecture directly on individual DNA fibers, making it especially powerful for plant genetics and cistromics. It layers high-resolution chromatin accessibility and protein-binding information onto endogenous DNA methylation and the accurate mapping provided by long-read sequencing, enabling genome-wide insight even in highly repetitive regions.

Importantly, the sensitivity of accessibility labeling and single-strand resolution of native long-read sequencing make it possible to directly link genetic variants to functional consequences in chromatin accessibility and protein binding.

If you’re attending , stop by the EpiCypher, Inc. Booth 329 to learn more!
🔗 https://www.cell.com/trends/plant-science/abstract/S1360-1385(25)00358-9

01/12/2026

Day 1 at PAG is a wrap ✅ Thank you to everyone who visited our booth yesterday and jumped into conversations about Fiber-seq and beyond with our team. We stayed busy, and we loved meeting so many scientists in person! 🔬🧬
If you have not stopped by yet, come see us today at booth 329. Also, do not forget to catch Keith and Hannah’s posters during today’s poster sessions.

01/09/2026

We are excited to share another PAG 33 poster from EpiCypher!

Hannah Devens, PhD is presenting poster P343: Advancing Agricultural Epigenetics with Direct Multiomic Mapping of DNA Methylation and Chromatin Features on January 12, 3:00 PM to 4:30 PM. 🌱🧬

If you are attending, stop by to say hello. If you cannot make it in person, you can download the poster here: https://explore.epicypher.com/posters/DNAme/pag2025