01/30/2026
🌿 A Peek Behind the Science of Herbal Extraction and why chemistry is so important 🧪🌱
One thing I see often in the herbal space is the idea that high-proof alcohol is always the “best” or most effective way to extract herbs.
When it comes to mullein for example, the science tells a more nuanced story.
If mullein is being used to support the respiratory system and overall lung comfort, research shows that water-based preparations are especially well-suited (Tyler, 1993; Nadeem et al., 2020) 💧
Here’s why.
Some of mullein’s most well-known constituents are mucilage and saponins. These are water-soluble (polar) compounds, meaning they extract best in hot water, such as teas, infusions, decoctions, or syrups (Marston & Hostettmann, 1991) ☕🌱
This is one reason traditional herbalism has long relied on water preparations of mullein for respiratory comfort and seasonal wellness support (Grieve, 1981; Mabey, 1988).
In laboratory studies comparing different solvents, aqueous (water-based) mullein extracts demonstrated stronger activity than alcohol extracts, and researchers specifically noted that hot water infusions and decoctions were particularly effective for respiratory-focused applications (Nadeem et al., 2020) 📊🧪
But where does alcohol (ethanol) fit in?
Alcohol extractions tend to pull out more:
• Flavonoids
• Phenols
• Alkaloids
• Other alcohol-soluble compounds
These constituents are commonly associated with antioxidant support and overall systemic balance, rather than the soothing, moistening qualities mullein is traditionally known for (Nadeem et al., 2020) ❤️✨
👉 The takeaway?
It’s neither water or alcohol that is the answer; It’s intention. Basically, scientists like me ask: "what am I trying to achieve with this extraction?"
Different solvents extract different plant compounds, and thoughtful herbalism means choosing the extraction method that aligns with the intended use and is based on documented research and ethnobotony 🌿⚖️
If someone says just alcohol, or even just water is always the answer, they’re not trying to mislead. They’re just overlooking the chemistry.
And in herbalism, chemistry matters! 🧪🌱
If you're wondering, Go-To organics uses both ethanol (and) water to get (all) of the plant's benefits! Dosage recommendations are based on well-established research too!
You can always feel confident that you're getting the absolute best with Go-To Organics! https://go-toorganics.com/
📘 References:
◾️Grieve, M. (1981). A modern herbal. Penguin Books.
◾️Mabey, R. (1988). The new age herbalist. Macmillan.
◾️Marston, A., & Hostettmann, K. (1991). Saponins. Cambridge University Press.
◾️Nadeem, A., et al. (2020). Verbascum thapsus versatile polarity extracts: GC-MS analysis, phytochemical profiling, antibacterial potential and antioxidant activity. Saudi Journal of Biological ◾️Sciences, 27(1), 257–264. https://doi.org/10.1016/j.sjbs.2019.10.004
◾️Tyler, V. E. (1993). The honest herbal: A sensible guide to the use of herbs and related remedies (3rd ed.). Pharmaceutical Products Press.