Mushroom Wisdom

Mushroom Wisdom A Global Leader in Mushroom Dietary Supplements including; Maitake D-Fraction and SX-Fraction, Lion's For more than 30 years Mushroom Wisdom, Inc.
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(MWI) has continuously developed and produced the finest research supported mushroom products. While mushrooms have been used traditionally for thousands of years, Mushroom Wisdom actually began in 1991, as Maitake Products, Inc., with the goal of bringing the health and immune supporting benefits of the, at the time, relatively unknown Maitake mushroom to the U.S. *

The original and only product that was offered was Grifron® Maitake, a simple, straightforward whole Maitake mushroom powder that offered a full range of Maitake’s actions. As researchers further explored this promising mushroom they found it contained a potent, unique beta glucan that was orally effective for supporting healthy immune function.* This became known as D-fraction. Maitake D-Fraction® PRO 4X, the company’s flagship product, is now available in a quick and easy “spray” form. Maitake D-Fraction “EZ” Spray is convenient for “on-the-go” administration. Further research on the Maitake mushroom led to discoveries related to its promising actions for supporting healthy blood sugar and insulin functions.* As a result of these studies the SX-fraction was born. After 10 years of being a “one mushroom” company we introduced a line of single mushrooms, all “super” enhanced by high quality mushroom fruiting body and unique mushroom extracts. This “Super” mushroom line includes Agaricus, Chaga, Coriolus, Cordyceps, Lion’s Mane, Meshima, Reishi, Shiitake and Tremella. MWI recently introduced Super Poria, based on their research of this mushroom and unique mushroom extract. By 2010 the company acknowledged its role as a leader in the mushroom category by changing its name to, Mushroom Wisdom Inc., to better reflect its diversity of products. By embracing the word “wisdom” as part of its new company name, MWI honors the thousands of years of traditional use of these mushrooms, while also emphasizing its industry leading commitment to furthering our knowledge and understanding with scientific research. As an industry and category leader, MWI is committed to offering the safest and most effective mushroom and mushroom extract supplements. MWI has developed proprietary extractions of several mushrooms to further enhance their beneficial actions. MWI has supported and continues to support investigations into the wondrous world of mushrooms at respected research institutions, such as Georgetown University, New York Medical College, and Shizuoka University in Japan as well as by renown researchers such as Harry Preuss, MD, Sensuke Konno, PhD, and Hirokazu Kawagishi, PhD. All MWI products are manufactured in a cGMP facility in the U.S with all mushroom materials verified for identity. Having celebrated their first 25 years in business last year, Mushroom Wisdom is looking forward to another 25 outstanding years offering you the finest mushroom supplements grounded in tradition, expanded by research.

*These statements have not been evaluated by the Food and Drug Administration. Mushroom Wisdom products are not intended to diagnose, treat, cure or prevent any disease.

Sometimes the most profound wisdom comes in simple equations.Maitake and Shiitake mushrooms have been revered separately...
02/23/2026

Sometimes the most profound wisdom comes in simple equations.

Maitake and Shiitake mushrooms have been revered separately in traditional healing systems for centuries. But researchers began noticing something remarkable when these two were studied together — their combined effect on immune function significantly exceeded what either mushroom accomplished alone.*

Maitake brings its celebrated D-fraction beta-glucans, among the most researched immune-supporting compounds in the mushroom kingdom. Shiitake contributes its own distinctive polysaccharides, including the well-studied lentinan, along with eritadenine and a rich spectrum of nutrients that support immune resilience and cardiovascular health.*

Together, they activate and modulate immune response through complementary pathways — a beautiful example of nature's intelligence at work.*

This is what true synergy looks like: not just addition, but amplification.
Mushroom Wisdom's Maitake and Super Shiitake bring this time-honored combination into a carefully crafted supplement backed by real science.*

Some combinations just work. This is one of them.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

02/21/2026

Chanterelle with heart.
(couldn't find the photographer)

02/20/2026
Beyond Immunity: Shiitake's Broader Gift to Your HealthShiitake (Lentinula edodes) is celebrated for immune support, but...
02/19/2026

Beyond Immunity: Shiitake's Broader Gift to Your Health

Shiitake (Lentinula edodes) is celebrated for immune support, but this remarkable mushroom has so much more to offer. Here are some of its most compelling non-immune benefits:

* Cardiovascular Support ~ Eritadenine and beta-glucans help promote healthy cholesterol levels and vascular tone
* Liver Health ~ Valued in Traditional Chinese Medicine for supporting liver function and natural detoxification
* Skin Vitality ~ Kojic acid and antioxidants help promote an even, luminous complexion and protect against premature aging
* Metabolic Balance ~ Supports healthy body composition and the kind of gut environment that underpins sound metabolic function
* Bone Support ~ One of nature's rare plant-based sources of vitamin D, contributing to healthy calcium absorption and bone density
* Antioxidant Protection ~ Rich in L-ergothioneine, a unique compound the body actively delivers to tissues under the greatest oxidative stress

Shiitake reminds us that true nourishment works across the whole of who we are, not just one system at a time. When a single mushroom can touch the heart, liver, skin, metabolism, bones, and cells all at once, that is worth paying attention to.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Power of Quiet Resilience.Some of the most profound strength in nature doesn't announce itself. It simply endures, a...
02/19/2026

The Power of Quiet Resilience.

Some of the most profound strength in nature doesn't announce itself. It simply endures, adapts, and continues to nourish life season after season.

Shiitake has been doing exactly that for thousands of years. Long before modern science caught up, traditional healers in Asia recognized this remarkable mushroom as a source of deep, sustained vitality. Today, research continues to illuminate what ancient wisdom already knew: shiitake supports healthy immune function and liver health in ways that quietly, consistently work in the background of our lives.*

Resilience isn't always dramatic. Sometimes it looks like steady immune surveillance. Sometimes it's the body's ability to process, filter, and renew. Shiitake helps nourish all of that.*

In a wellness culture that often chases the next big thing, there's something grounding about turning to a mushroom that has simply never stopped delivering. Quiet. Consistent. Resilient.

Discover Mushroom Wisdom's Super Shiitake and give your body the kind of support that endures.*

https://mushroomwisdom.com/product/super-shiitake-120-tablets/
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Supporting Male Vitality: What the Research Shows About CordycepsFor centuries, Traditional Chinese Medicine has valued ...
02/18/2026

Supporting Male Vitality: What the Research Shows About Cordyceps

For centuries, Traditional Chinese Medicine has valued Cordyceps sinensis as a tonic for male vitality and reproductive wellness. Modern research is now illuminating the mechanisms behind this traditional wisdom, revealing how this remarkable mushroom supports the body's natural hormone production pathways.

A comprehensive review published in the Journal of Food and Drug A**lysis examined how Cordyceps sinensis and its primary bioactive compound, cordycepin, support healthy testosterone production in Leydig cells, the specialized testicular cells responsible for hormone synthesis. In both cell culture and animal studies, the mushroom's water-soluble protein fractions and polysaccharide-protein complexes demonstrated the ability to support healthy testosterone levels and enhance the body's steroidogenic pathways.
What makes the biology particularly elegant is cordycepin's mechanism of action. Due to its structural similarity to adenosine, cordycepin naturally engages the same cellular signaling pathways (including PKA) that the body uses to regulate hormone synthesis. Rather than overriding natural processes, cordycepin works harmoniously with the body's existing systems, supporting what healthy cells already do.

The research also suggests potential benefits for supporting normal s***m quality and motility, as well as maintaining cellular health in reproductive tissues. The water-soluble proteins (F2) and polysaccharide-protein complexes (F3) appear to be the most bioactive fractions, underscoring the value of whole-mushroom preparations that preserve the complete matrix of beneficial compounds.

This science-backed traditional wisdom points to Cordyceps sinensis as a valuable ally for men seeking to support healthy hormone balance, maintain reproductive wellness, and nourish overall vitality through natural means.

Citation: Chen YC, Chen YH, Pan BS, Chang MM, Huang BM. Functional study of Cordyceps sinensis and cordycepin in male reproduction: A review. J Food Drug A**l. 2017;25(1):197-205. doi:10.1016/j.jfda.2016.10.020

Shiitake: Ancient Wisdom for Modern Immune SupportFor centuries, Shiitake mushrooms have been treasured in Traditional C...
02/17/2026

Shiitake: Ancient Wisdom for Modern Immune Support
For centuries, Shiitake mushrooms have been treasured in Traditional Chinese Medicine for their ability to nourish vitality and support the body's natural defenses. Today, science confirms what tradition has long understood: Shiitake contains beta-glucans and other bioactive compounds that help maintain balanced immune function.
A balanced immune response means your body responds appropriately to challenges without overreacting or underperforming. Shiitake supports this delicate equilibrium, helping your immune system stay centered and responsive.*
Whether you're navigating seasonal transitions or simply want to support your body's innate wisdom, Mushroom Wisdom's Super Shiitake provides concentrated, bioavailable support from this time-honored functional mushroom.*

Key Benefits:
• Supports balanced immune function*
• Provides beta-glucans and polysaccharides*
• Promotes overall vitality and well-being*
• Backed by both traditional use and modern research*

Discover the immune-supportive power of Super Shiitake from Mushroom Wisdom.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Your body's own antioxidant defense system represents one of nature's most elegant protective mechanisms. Unlike antioxi...
02/15/2026

Your body's own antioxidant defense system represents one of nature's most elegant protective mechanisms. Unlike antioxidants consumed through diet, endogenous antioxidants like superoxide dismutase (SOD), catalase, and glutathione peroxidase are produced within your cells, offering continuous protection against oxidative stress. Cordyceps has been shown to stimulate this internal production, essentially teaching your body to strengthen its own defenses rather than relying solely on external sources. This activation of your innate protective capacity reflects the traditional Chinese medicine understanding of Cordyceps as a tonic that builds fundamental vitality and resilience.*

Research demonstrates that Cordyceps compounds, particularly cordycepin and polysaccharides, can upregulate the expression of genes responsible for endogenous antioxidant production. This means that rather than simply neutralizing free radicals like dietary antioxidants do, Cordyceps supports your cellular machinery in creating a more robust, sustainable defense system. For those seeking to nourish their body's natural protective capacities, particularly during periods of physical or mental stress, this mushroom offers a time-honored approach validated by modern science. The Super Cordyceps formula provides this benefit in a concentrated, bioavailable form.*

02/13/2026

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East Rutherford, NJ
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Science Complementing Ancient Wisdom

For almost three decades Mushroom Wisdom, Inc. (MWI) has continuously developed and produced the finest research supported mushroom products. While mushrooms have been used traditionally for thousands of years, Mushroom Wisdom actually began in 1991, as Maitake Products, Inc., with the goal of bringing the health and immune supporting benefits of the, at the time, relatively unknown Maitake mushroom to the U.S. * The original and only product that was offered was Grifron® Maitake, a simple, straightforward whole Maitake mushroom powder that offered a full range of Maitake’s actions. As researchers further explored this promising mushroom they found it contained a potent, unique beta glucan that was orally effective for supporting healthy immune function.* This became known as D-fraction. Maitake D-Fraction® PRO 4X, the company’s flagship product, is now available in a quick and easy “spray” form. Maitake D-Fraction “EZ” Spray is convenient for “on-the-go” administration. Further research on the Maitake mushroom led to discoveries related to its promising actions for supporting healthy blood sugar and insulin functions.* As a result of these studies the SX-fraction was born. After 10 years of being a “one mushroom” company we introduced a line of single mushrooms, all “super” enhanced by high quality mushroom fruiting body and unique mushroom extracts. This “Super” mushroom line includes Agaricus, Chaga, Coriolus, Cordyceps, Lion’s Mane, Meshima, Reishi, Shiitake and Tremella. MWI recently introduced Super Poria, based on their research of this mushroom and unique mushroom extract. By 2010 the company acknowledged its role as a leader in the mushroom category by changing its name to, Mushroom Wisdom Inc., to better reflect its diversity of products. By embracing the word “wisdom” as part of its new company name, MWI honors the thousands of years of traditional use of these mushrooms, while also emphasizing its industry leading commitment to furthering our knowledge and understanding with scientific research. As an industry and category leader, MWI is committed to offering the safest and most effective mushroom and mushroom extract supplements. MWI has developed proprietary extractions of several mushrooms to further enhance their beneficial actions. MWI has supported and continues to support investigations into the wondrous world of mushrooms at respected research institutions, such as Georgetown University, New York Medical College, and Shizuoka University in Japan as well as by renown researchers such as Harry Preuss, MD, Sensuke Konno, PhD, and Hirokazu Kawagishi, PhD. All MWI products are manufactured in a cGMP facility in the U.S with all mushroom materials verified for identity. Looking forward to our 30th Anniversary in 2021, Mushroom Wisdom is proud to continue offering you the finest mushroom supplements grounded in tradition, expanded by research. *These statements have not been evaluated by the Food and Drug Administration. Mushroom Wisdom products are not intended to diagnose, treat, cure or prevent any disease.