Neuromics

04/04/2026

Their important findings demonstrate a genetic rationale for drug prioritization. Importantly, the results present targets and potential avenues for therapeutic intervention in AD and SVD, which have the potential to
📓 Kevin Chris Ziegler, Aydan Askarova, Alexi Nott et al (2025). The Brain Neurovascular Epigenome and Its Association with Dementia. Neuron. doi: 10.1016/j.neuron.2025.10.001 https://lnkd.in/gJKRkmH9
✅ Meet Neuromics AssayIQ-AI Assistant-https://www.neuromics.com/assayiq
Nicolas Hubacz, M.S. Kathleen Stark, Lori Johnson Caltag hashtag , hashtag , hashtag , hashtag

04/04/2026

This just crossed my radar. It could be of interest to students graduating this year.
Seminar: The Blueprint for Admission to the Most Selective Colleges

The videos will help you understand the steps and the college admissions process for high-school students. Learn how to stand-out.

04/02/2026

Congratulation
Orange cat? Purposely ironic?
🧠The Orange Cat Brain Atlas is here.
Using cutting-edge electron microscopy techniques, our scientists have published the first comprehensive cellular map of the orange cat brain.
The new atlas reveals a single, highly specialized neuron responsible for key behaviors like staring at walls, knocking objects off tables, and doing the "zoomies" at 3 am.
"This accomplishment is a neuroscience milestone, but it also springs forth additional questions," said Dr. Apryl Fuhls, lead investigator of the study team. "How does behavior arise from a single neuron? How did the orange cat's brain evolve? Is the brain cell always in use, or is it just occasionally active?"

04/01/2026

Can anyone guess what this image represents?
hint: It's something the
lack.

03/31/2026

Yvonne Adams and Anja T.R. Jensen (University of Copenhagen) manufactured Organioids using Neuromics' Primary Human Astrocytes https://tinyurl.com/HumanAstrocytes and Human Brain Microvascular Endothelial Cells https://tinyurl.com/HuBMVECS to study Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood–brain barrier in cerebral malaria.
https://www.neuromics.com/primary-human-astrocyte-and-human-umbilical-cell-huves-organoids

Cerebral malaria (CM) is caused by the binding of Plasmodium falciparum–infected erythrocytes (IEs) to the brain microvasculature, leading to inflammation, vessel occlusion, and cerebral swelling.

Image 1: 3D BBB spheroids are composed of three different cell types. (A) FACS histogram showing pericytes (NG2, neural/glial antigen 2), astrocytes (GFAP, glial fibrillary acidic protein), and human cerebral microvascular endothelial cells (hCMEC/D3 and CD31).

This is first time the presence of intact, mature P. falciparum IEs within brain microvascular endothelial cells both in vitro and in vivo. The data on the enhanced binding and internalization of IEs suggest that the same approach will be necessary to counteract not only the effects of cytoadhesion but also the subsequent contribution to potentially lethal brain swelling in CM. Neuroscience News and Research

03/28/2026

🧠 You're looking at Parkinson's disease forming inside a single neuron.

✅️ Note-Neuromics Provides Neuroscientists iPSC-Derived Dopaminegic Neurons
This iPSC-derived dopaminergic neuron was treated with α-synuclein fibrils and IFN-γ for 14 days. Red is TH (dopaminergic marker), green is phosphorylated α-synuclein (S129) — the pathological form found in patient Lewy bodies.

The bright yellow-green mass in the soma is a Lewy body-like inclusion — but look closely. It's not a homogeneous sphere. It's made up of hundreds of discrete phospho-synuclein-positive fibrillization events, each one a separate aggregation seed recruited and compacted into the growing mass. The fibrillization process itself, frozen mid-assembly.

Now look at the neurites — those green puncta lining the processes are the same thing at an earlier stage, being actively transported outward. It's prion-like propagation caught in progress.

Why S129 phosphorylation matters: less than 4% of α-synuclein carries this modification in a healthy brain. In Parkinson's disease Lewy bodies, it's over 90%.

🔗 www.arminbayati.org

03/26/2026

🧠 Fascinating and Informative
🔬 Walk with Nobel Prize-winning Carolyn Bertozzi, a Nobel Prize–winning chemist at Stanford Medicine, who uses chemical biology to understand disease and develop new treatments. Hear what sparked her love of science—and the superpower she wishes she had. Stanford University School of Medicine,

03/25/2026

🧬 BREAKING: The approved a cancer drug in 2024 that doesn't use chemotherapy.
✅ Instead, it powers up the immune cells you were BORN with.
✅ In trials, 62% of patients had all detectable cancer disappear completely.
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🧠 Meet Neuromics AssayIQ-https://tinyurl.com/AI-Assistant-Neuromics

03/24/2026

🧠 Birth of a Neuron. This is how a neuron looks maturing.
✅ Glutamatergic neurons are the primary excitatory neurons in the human central nervous system (CNS), using glutamate to stimulate target neurons and accounting for 60–70% of brain synapses. These neurons are essential for learning, memory, and cognitive function, but their dysfunction is linked to neurological conditions.
✅ Meet Neuromics AssayIQ-https://tinyurl.com/AssayIQ-AI-Assistant.

03/24/2026

A self-evident truth.

Transportation Secretary Sean Duffy was facing criticism and growing calls to resign on Monday after two pilots were killed and dozens of people were injured during a collision involving an Air Canada plane and a fire truck at LaGuardia Airport. This was the second fatal crash under Duffy's leadersh...