01/27/2026
ESTRIOL VS ESTRADIOL: WHAT MOST WOMEN DON’T KNOW
Not all estrogen is the same—and understanding the difference matters.
In this video, Dr. Michelle explains how bioidentical topical hormone therapy works and why some prescriptions include both estriol and estradiol.
✨ Estriol is a weaker estrogen and may be added for patients who have concerns about using higher amounts of regular estradiol or who have a family history of female cancers. It offers a gentler way to replace estrogen, with minimal systemic absorption and calming benefits.
✨ Estradiol is the primary estrogen that supports energy, mood, bone health, and overall hormonal balance.
Some formulations may also include progesterone and a small amount of testosterone for more complete hormone support.
🌿 About bioidentical hormones:
• Made from plant-based hormones extracted from plant sterols
• Compounded by specially trained compound pharmacists
• Customized dosing based on each patient’s individual needs
💧 How it’s used:
• Applied topically, usually once or twice daily
• Best applied after showering when veins are more dilated
• Rub into an area with good circulation, then wash hands
⏳ What to expect:
• Benefits may be noticed in 2–3 weeks
• Consistent daily use is important
• Hormone levels should be checked after 6–8 weeks
💡 Additional option:
• Vaginal estriol is also available and can be very effective for relieving menopausal vaginal dryness.
Hormone therapy is not one-size-fits-all. The right approach is personalized, monitored, and tailored to you.
