11/14/2025
The APOE4 gene has long been tied to Alzheimer’s.
But new science says your genes don’t seal your fate.
APOE4 affects how your brain handles cholesterol, inflammation, and blood vessel health, all things you can support early.
The full picture includes more than just one gene.
Inflammation genes like IL6, detox genes like SOD2, and methylation genes like MTHFR can also shape your brain’s resilience over time.
It’s not just about memory loss. It’s about prevention.
Testing your DNA can reveal what your brain might face decades from now and what you can do about it now.
Sources:
https://www.nature.com/articles/s41380-025-03274-9
https://med.stanford.edu/news/insights/2025/09/rethinking-alzheimers-gene-variant-apoe4.html
https://www.npr.org/sections/shots-health-news/2025/09/02/nx-s1-5522371/alzheimers-risk-apoe4-genes-scientists-treatment-advocacy