04/11/2021
*MELANOPSIN, a retinal cell protein in your eye (different than rod and cone cells and only discovered in 2002), uses light to affect your circadian clock.
*When melanopsin is stimulated by light, it wires a message to the brain to reset your internal clock to the light it is perceiving - telling your brain it is daytime and to pump out time specific hormones like cortisol and turn off melatonin production.
*Melanopsin is triggered by blue light (all of your digital screens) and minimally stimulated by red light… hence the decision to offer red lights on phones in the evening.
*Melanopsin's effects on regions of the brain give insight to:
-People with migraines who are more sensitive to screen light
-People who don't go outdoors in daylight and feel low energy, depression, or brain fog
-Those with insomnia and anxiety
*Your circadian clock is set to optimize hormone production and biological functions at finely tuned timings. Most of us today have put the system into haywire. The more you are "functioning" at an off schedule, the more likely it is having a chronic negative effect on your health. Circadian disruption has been associated with gastrointestinal diseases, obesity, diabetes, cancer, and cardiovascular disease.
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REFERENCES:
S. Panda et al., Melanopsin (Opn4) Requirement for Normal Light-Induced Circadian Phase Shifting," Science 298, no.5601(2002):2213-16.
S. Panda. The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight. New York, Rodale Books, 2018.
N.F. Ruby etc al., "Role of Melanopsin in Circadian Responses to Light," Science 298, no. 5601 (2002):2211-13.
S. Sookoian etc al., "Effects of Rotating Shift Work on Biomarkers of Metabolic Syndrome and Inflammation," Journal of Internal Medicine 261, no.3(2007):285-92.