International Perfusion Association

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Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgica...
04/01/2026

Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgical planning, intraoperative precision, and postoperative monitoring. Tools such as AI-ECG, automated imaging, and predictive analytics improve risk stratification and outcomes.

Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgical planning, intraoperative precision, and postoperative monitoring. Tools such as AI-ECG, automated imaging, and predictive analytics improve risk stratification and outcomes. Whil...

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 inclu...
03/31/2026

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied alternatives, while nafamostat, prostaglandin E1, circuit modifications, anticoagulation-free protocols, and newer monitoring tools remain emerging areas.

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied alternatives, while nafamostat, prostaglandin E1, circuit modifications, anticoagulation-fr...

This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across...
03/30/2026

This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across U.S. states and Pediatric Emergency Referral Regions. Researchers identified 258 pediatric ECMO centers and 169 ECPR centers, finding major differences in direct access, especially in rural areas.
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This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across U.S. states and Pediatric Emergency Referral Regions. Researchers identified 258 pediatric ECMO centers and 169 ECPR centers, finding major differences in direct access, especiall...

This meta-analysis examined how much end-tidal sevoflurane is needed to maintain appropriate anesthetic depth during car...
03/30/2026

This meta-analysis examined how much end-tidal sevoflurane is needed to maintain appropriate anesthetic depth during cardiopulmonary bypass. Across five prospective studies involving 129 adults, the pooled estimate was 0.88 vol% for a BIS target of 40–60. Older patients required less sevoflurane, while body temperature did not significantly change dosing needs.

This meta-analysis examined how much end-tidal sevoflurane is needed to maintain appropriate anesthetic depth during cardiopulmonary bypass. Across five prospective studies involving 129 adults, the pooled estimate was 0.88 vol% for a BIS target of 40–60. Older patients required less sevoflurane, ...

This mini review compares the three main temporary mechanical circulatory support options for cardiogenic shock: Impella...
03/28/2026

This mini review compares the three main temporary mechanical circulatory support options for cardiogenic shock: Impella, venoarterial extracorporeal life support (VA-ECLS), and intra-aortic balloon pump (IABP).

This mini review compares the three main temporary mechanical circulatory support options for cardiogenic shock: Impella, venoarterial extracorporeal life support (VA-ECLS), and intra-aortic balloon pump (IABP). It explains each device’s physiology, indications, risks, and evidence base, then prop...

This prospective cohort study examined 102 adults undergoing first-time isolated on-pump CABG and compared three membran...
03/28/2026

This prospective cohort study examined 102 adults undergoing first-time isolated on-pump CABG and compared three membrane oxygenators: Capiox FX25, Inspire 8, and Inspire 8F. The Capiox FX25 showed the lowest arterial gaseous microemboli volume and the best volume reduction, while postoperative delirium occurred in 29.4% overall and was least frequent with Capiox FX25.

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This experimental rat-heart study tested whether ranolazine protects the myocardium through pathways similar to ischemic...
03/27/2026

This experimental rat-heart study tested whether ranolazine protects the myocardium through pathways similar to ischemic preconditioning. Using a Langendorff ischemia-reperfusion model, ranolazine reduced infarct size, LDH, CK-MB, troponin I, and improved ventricular function.

This experimental rat-heart study tested whether ranolazine protects the myocardium through pathways similar to ischemic preconditioning. Using a Langendorff ischemia-reperfusion model, ranolazine reduced infarct size, LDH, CK-MB, troponin I, and improved ventricular function. These benefits were lo...

This single-center retrospective cohort study examined 229 neonatal and pediatric VA-ECLS patients and found that early ...
03/27/2026

This single-center retrospective cohort study examined 229 neonatal and pediatric VA-ECLS patients and found that early hyperoxia was common, affecting 79% of cases.

This single-center retrospective cohort study examined 229 neonatal and pediatric VA-ECLS patients and found that early hyperoxia was common, affecting 79% of cases. Severe hyperoxia, defined as PaO2 above 300 mmHg, was linked to more cardiovascular or renal complications, but it was not independent...

This study evaluated mitral transcatheter edge-to-edge repair (M-TEER) in advanced heart failure patients who might othe...
03/27/2026

This study evaluated mitral transcatheter edge-to-edge repair (M-TEER) in advanced heart failure patients who might otherwise have been reasonable candidates for left ventricular assist device (LVAD) therapy.

This study evaluated mitral transcatheter edge-to-edge repair (M-TEER) in advanced heart failure patients who might otherwise have been reasonable candidates for left ventricular assist device (LVAD) therapy. Among 129 such patients from the OCEAN-Mitral Registry, procedural success was high at 96%,...

This institutional retrospective study evaluated 72 patients bridged to heart transplant with the Impella 5.5 and compar...
03/26/2026

This institutional retrospective study evaluated 72 patients bridged to heart transplant with the Impella 5.5 and compared outcomes for support durations of 14 days or less versus more than 14 days. Prolonged support did not worsen 1-year survival, graft rejection, length of stay, or major complications.

This institutional retrospective study evaluated 72 patients bridged to heart transplant with the Impella 5.5 and compared outcomes for support durations of 14 days or less versus more than 14 days. Prolonged support did not worsen 1-year survival, graft rejection, length of stay, or major complicat...

This retrospective single-center study compared four cardioplegia strategies in 543 patients undergoing minimally invasi...
03/26/2026

This retrospective single-center study compared four cardioplegia strategies in 543 patients undergoing minimally invasive aortic valve replacement from 2010 to 2025.

This retrospective single-center study compared four cardioplegia strategies in 543 patients undergoing minimally invasive aortic valve replacement from 2010 to 2025. After inverse probability weighting balanced baseline differences, Calafiore and Custodiol were associated with less postoperative at...

This preclinical rodent liver study tested whether Poloxamer 188 and Ficoll PM70 could reduce red blood cell hemolysis d...
03/26/2026

This preclinical rodent liver study tested whether Poloxamer 188 and Ficoll PM70 could reduce red blood cell hemolysis during normothermic machine perfusion. Both polymers lowered free hemoglobin and improved preservation of liver sinusoidal endothelial cells in donation after brain death and warm ischemia models.

This preclinical rodent liver study tested whether Poloxamer 188 and Ficoll PM70 could reduce red blood cell hemolysis during normothermic machine perfusion. Both polymers lowered free hemoglobin and improved preservation of liver sinusoidal endothelial cells in donation after brain death and warm i...

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