11/11/2025
A new study from the University of South Carolina has linked gum disease to damage in the brain’s white matter — the tissue responsible for communication between different brain regions. Researchers found that people with periodontal disease had significantly higher levels of white matter hyperintensities, a marker of small vessel disease.
This means persistent gum inflammation might not just harm the mouth — it could influence brain health, potentially increasing the risk of stroke and cognitive decline. Chronic oral bacteria and inflammation may trigger changes in blood vessels, silently damaging the brain over time.
Scientists emphasize this doesn’t prove direct cause and effect yet, but the findings are a serious reminder that oral hygiene impacts more than just teeth. Keeping gums healthy through regular dental care, cleaning, and early treatment of bleeding or swelling could also help protect long-term brain health.
Good oral health is whole-body health — and the mouth may be the first place your brain shows warning signs.
🔬 Source:
Meyer J, Martin C, Wood S, et al.
Neurology: Open Access. 2025;1(4).
doi:10.1212/WN9.0000000000000037
