03/15/2026
People who wear dentures often use denture adhesive to keep them secure. Some denture adhesives contain zinc. While zinc is safe in small amounts, using too much adhesive can lead to high zinc levels in the body. Excess zinc can interfere with copper absorption and may cause health problems such as anemia. Very high levels of zinc can also lead to nerve problems, including numbness, tingling, muscle weakness, and digestive issues.
Zinc-free denture adhesives are a safer option because they reduce the risk of zinc buildup while still helping dentures stay in place.
If you need to use large amounts of adhesive, your dentures may not fit properly. In that case, you should see your dentist.
Regular dental checkups are still important, even if you no longer have natural teeth. During these visits, the dentist can check for signs of oral cancer, make sure your dentures fit well, evaluate your bite, and give advice on proper denture care and safe products.
Seek medical attention if you experience numbness, tingling, or weakness.
This information was provided by the U.S. Food and Drug Administration.