12/16/2025
DHEA for Women Part 1: What It Is & How It Works
If you’ve been hearing more about DHEA lately, you’re not alone. Women are exploring it for energy, mood, libido, skin/hair support, and genitourinary symptoms of menopause (GSM).
What is DHEA?
Dehydroepiandrosterone (DHEA) is a hormone primarily made by your adrenal glands and, to a lesser extent, the ovaries. It’s a prohormone—your tissues can locally convert it into small amounts of estrogens and androgens (like testosterone) as needed. This “local conversion” is called intracrine metabolism. Circulating DHEA levels peak in early adulthood and gradually decline with age, which is one reason it’s discussed in midlife health.
How does DHEA work?
Inside target tissues (skin, vaginal epithelium, hair follicles, bone, brain), enzymes convert DHEA into estradiol/estrone and testosterone/dihydrotestosterone in tiny, localized amounts. Because much of this happens inside tissues, blood levels of estrogen/testosterone may not rise dramatically, yet symptoms in those tissues can improve.
Where DHEA may help
Evidence is evolving, but research and clinical experience suggest potential benefits for some women:
* GSM (vaginal dryness, discomfort, painful in*******se)
* Sexual function/libido
* Mood/energy/well-being
* Skin/hair
Important: DHEA is not a cure-all. Benefits, dosing, and risks should be reviewed with your doctor—especially if you have hormone-sensitive conditions.��
The bottom line
DHEA is a versatile prohormone that midlife women may leverage—either locally (vulvar/vaginal) or systemically—for select goals.
In the U.S. it’s over-the-counter, but in many countries it’s prescription-only, a reminder that medical oversight matters. Options like Julva® and Well Products’ Saw Palmetto for Women with DHEA + Biotin exist in the supplement space, while Intrarosa® offers an FDA-approved prescription path for GSM. The “right” approach is personal—guided by your history, goals, and careful monitoring.�
ďż˝