02/06/2026
💡 Did you know that Acetyl-L-Carnitine can potentially help reduce depressive symptoms? Recent studies suggest it might be worth considering! Take a peek at the latest findings and see if it could work for you.
References:
Veronese N, Stubbs B, Solmi M, Ajnakina O, Carvalho AF, Maggi S. Acetyl-L-Carnitine Supplementation and the Treatment of Depressive Symptoms: A Systematic Review and Meta-Analysis. Psychosom Med. 2018 Feb/Mar;80(2):154-159. doi: 10.1097/PSY.0000000000000537. PMID: 29076953.
Cuccurazzu B, Bortolotto V, Valente MM, Ubezio F, Koverech A, Canonico PL, Grilli M. Upregulation of mGlu2 receptors via NF-κB p65 acetylation is involved in the Proneurogenic and antidepressant effects of acetyl-L-carnitine. Neuropsychopharmacology. 2013 Oct;38(11):2220-30. doi: 10.1038/npp.2013.121. Epub 2013 May 14. PMID: 23670591; PMCID: PMC3773672.
Nie LJ, Liang J, Shan F, Wang BS, Mu YY, Zhou XH, Xia QR. L-Carnitine and Acetyl-L-Carnitine: Potential Novel Biomarkers for Major Depressive Disorder. Front Psychiatry. 2021 Sep 30;12:671151. doi: 10.3389/fpsyt.2021.671151. PMID: 34658942; PMCID: PMC8514700.