11/13/2025
Hey everyone, back with another informative video about your thyroid health.
In this Thyroid Thursday, I’m breaking down how starting estrogen replacement therapy can unexpectedly make hypothyroid symptoms worse — and even lead to being prescribed more thyroid medication. I share a real case of a woman who felt fine on 60 mg of NP Thyroid until her doctor added estrogen therapy. Soon after, she began experiencing more fatigue and brain fog, and her labs showed lower free T3. Her practitioner increased her thyroid meds, but that only made her anxious, irritable, and even more symptomatic.
In this video, I explain how estrogen increases binding globulins in the blood — which can lower the amount of free, active thyroid hormone available. When you add estrogen to someone already dealing with inflammation, Hashimoto’s, or thyroid medication, that shift can create both hypo and hyperthyroid symptoms at the same time. If you’re on thyroid meds and considering hormone therapy, this episode will help you understand what’s happening and why.