03/19/2026
About Trent Knight, MPAS, PA-C
Trent Knight’s commitment to serving others began early, growing up in a Midwest military family. When medical limitations prevented him from pursuing military service, he redirected that passion into healthcare.
He earned his undergraduate degree from Chadron State College and went on to receive his Master’s in Physician Assistant Studies from the University of Nebraska Medical Center in 1996.
After moving to Arizona, Trent built a diverse medical background, working in the federal correctional system, urgent care, and as a solo provider in a rural emergency room. He also played a key role in establishing the City of Goodyear Wellness Clinic in 2008, where he provided care to police officers, firefighters, and their families.
During this time, he recognized the powerful impact of hormone replacement therapy and the lack of accessible, high-quality care in that space.
In 2019, Trent co-founded Optimal Men’s Center with his wife, Kerry Knight, PA-C. Together, they expanded their services to include hormone therapy for women, aesthetics, and weight loss through Optimal Health and Wellness Center.
Trent specializes in closely monitored testosterone replacement therapy (TRT), growth hormone therapies, and non-narcotic pain treatments. He is known for providing thorough, personalized care while maintaining a strong focus on patient comfort and discretion—especially for sensitive concerns like low testosterone, erectile dysfunction, and weight management.
His mission remains the same: helping patients achieve optimal health and a better overall quality of life.