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Nebraska Functional Medicine

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Grand Island, NE
Nebraska Functional Medicine

Nebraska Functional Medicine is an individualized, patient-centered, science-based clinic.

01/20/2026

Some of us are feeling the effects after the holidays have passed. A Forbes Health/OnePoll survey found that many Americans set New Year’s resolution goals related to health: 34% plan to lose weight and 32% aim to improve their diet and eat healthier.

Questions about fasting are common in our clinic. Is this something everyone should be doing? What are the pros and cons? Is this just another fad people talk about and change their mind in a few years?

Actually, fasting has been around for thousands of years for spiritual, cultural, and health reasons. It has recently gained renewed attention for potential benefits in metabolism, inflammation, longevity, and gut health. It’s important to keep in mind that fasting is not a “one-size-fits-all” approach. Here are some common questions we get:

🩵 What is fasting?
Fasting is the restriction of calorie intake for a specific period of time. Those time frames vary depending on the person and their health goals. It can range from a 12-hour overnight fast most days to having an occasional 24-hour fasting period (or longer).

The purpose of fasting is to give the body a break from constant digestion, so it can shift into repair, regulation, and metabolic flexibility. When you fast, the body will start using up “stored fuel”, such as glycogen and fat.

🩵 What are the potential benefits of fasting?
👉 Improved metabolism: Fasting helps the body shift from glucose-burning to fat-burning. This improves insulin sensitivity and reduces blood sugar fluctuations. It can also be helpful for individuals with insulin resistance, metabolic syndrome, or prediabetes.
👉 Reduced inflammation: Going periods without food can lower inflammatory signaling and oxidative stress. Many individuals notice improvements in joint pain, brain fog, skin abnormalities, and overall energy when they implement fasting appropriately.
👉 Cellular repair and autophagy: Autophagy is the body’s internal recycling system that removes damaged cells and supports cellular renewal. Fasting stimulates this system, leading to improved immunity, healthier aging, and longevity.
👉 Gut rest and microbiome support: When we’re constantly eating, our bodies are not allowed time to rest and repair. Fasting supports the migrating motor complex (MMC), which can reduce bacterial overgrowth and improve symptoms like bloating, reflux, and irregular bowel movements.
👉 Hormonal balance: Fasting also helps rebalance insulin, leptin, and ghrelin, which are all key hormones involved in appetite and energy regulation. We also see individuals with improved cortisol patterns and mental clarity.

🩵 Who might benefit from fasting?
👉 Individuals who struggle with insulin resistance or blood sugar dysregulation
👉 Individuals experiencing chronic inflammation
👉 Individuals who have digestive issues (often related to overgrowth or poor motility)
👉 Individuals who want to support longevity and cellular health
👉 Basically, everyone. We should all aim for a minimum of a 12 hour fast each day for optimal health!

🩵 What are some common mistakes people make with fasting?
👉 Fasting too long, too soon
👉 Skipping meals and not consuming enough protein
👉 Using fasting to compensate for a highly inflammatory diet
👉 Ignoring stress, poor sleep, or hormone imbalances
👉 Pushing through symptoms like dizziness, fatigue, or anxiety

Fasting should feel supportive, not punishing. It is a powerful therapeutic tool when used thoughtfully and strategically. Because each individual’s needs vary, we recommend fasting be personalized, implemented, and supported under the guidance of a healthcare professional.

The benefits of fasting depend on a multitude of factors: the individual’s overall health status, stress load, nutritional foundation, and both short- and long-term goals. When integrated correctly, fasting can be helpful for improving gut function, regulating hormones, reducing inflammation, and supporting metabolic health and longevity.

Ultimately fasting is an amazing, free tool you can use to optimize your health! Speak with us if you have questions about the right type of fasting for you personally. We’d love to help!

01/14/2026

Want energy so good it feels almost unfair? Meet NAD+.

NAD+ is all the rave right now, and it should be! 🙌 It's found in every cell of the body.

Levels naturally decline as we age, and can drop faster during times of stress or illness. In fact, by the age of 40, we've had a 40% reduction! This can look like wrinkles, brain fog, and decreased mobility. NAD+ plays a key role in energy production and DNA repair. Research has even linked low levels with fatigue and neurocognitive decline!

The most effective way to replenish NAD+? An infusion. (Not the supplements influencers are trying to sell you.)

NAD+ infusions can be customized and slowly infused over 1–2 hours to minimize the temporary “NAD flush,” which may feel like mild headache or stomach discomfort as cellular metabolism ramps up--a sign it's working!

If you’re feeling low on energy, mentally foggy, or just not quite yourself, give us a call - our team can help you decide whether NAD+ therapy is a good fit for you!

12/31/2025

New Years Eve 2025

I’m not sure how, but the end of 2025 is here. And it’s natural to reflect on all that happened in the span of 12 months. 365 days.

For me, thinking about 2025 feels like one giant exhale. Started the year finalizing design plans for our new space; while entering the last trimester of my fourth pregnancy. Before I knew it, I had a newborn and we were doing final walkthroughs of the space. Shortly after, we opened our doors for patients, with my one month old in tow.

I am grateful. I truly am. But I am ready for a new year. And instead of making “goals” or plans to do more, my challenge for you is to think about what you need less of—what do you need to let go? What isn’t serving you? What is stealing your energy and joy?

Majority of my patients get told to slow down. They are completely exhausted. Schedules are packed. There’s too many obligations. And a lack of fulfillment and wrecked adrenals as a result.

And I am going to take the same advice. Since opening NFM, it’s been nonstop. Nonstop good things! But with all the glitz and glam comes a lot of sacrifice.

So my prayer for all of us in 2026 is this—
May this New Year bring a slower pace. The strength to let go of things that don’t serve me. The confidence to say no when it steals a better yes. The courage and commitment to prioritize my health. And intentional time with those who fill my heart.

I wish you all abundant blessings and peace.
Love, Keri 🩵

12/25/2025

From all of our families to yours, Merry Christmas! ❤️

We pray your time with family is filled with food that nourishes you, connection that fuels your soul, and abundant peace and joy.

“Thanks be to God for His indescribable gift.” 2 Corinthians 9:15

12/23/2025

Wise words to remember this holiday season from Dr. Mark Hyman, M.D. 🩵

12/17/2025

Our kind of Christmas tree 🎄✨

Give the gift of staying healthy this season. PUR-C is wonderful for everyone on your list!

Give us a call at 308-390-2663 to take care of the last of your shopping. We ship! 🤍

11/24/2025

Our founder, Keri, has created a gift guide of some of her favorite things. All hand picked with clean and non-toxic living in mind! 🥰

You’ll find ideas for anyone on your list (including yourself!), that all support a healthy lifestyle. Some have special discounts too, so make note!

Click here to view Keri's gift guide: https://nefunctionalmedicine.com/keris-holiday-gift-guide/

11/22/2025

In the last two weeks alone, our Kaqun tub has seen everything from:

▫️Molluscum
▫️Chronic Lyme disease
▫️Pancreatic cancer
▫️Athletic injuries
▫️Chronic skin rash
▫️Breast cancer
▫️Autoimmune disease
▫️Mold illness
▫️Pregnancy
▫️Surgery recovery
▫️Metabolic disease
▫️Multiple sclerosis

Try Kaqun to see for yourself! Give us a call at 308-390-2663 to book your session.

11/19/2025

Cosmetic procedures are everywhere these days - breast implants, fillers, you name it. And while these treatments can absolutely boost confidence, there’s also a not-so-glamorous side of things: inflammation, strange symptoms, and something called biofilms that most people don’t even know exist.

At Nebraska Functional Medicine we see more and more patients connecting the dots between their cosmetic history and their whole-body health. So let’s break it all down in a way that actually makes sense.

Breast Implant Illness: Why People Are Talking About It.

“Breast implant illness” (BII) isn’t an official diagnosis, but thousands of women are experiencing eerily similar symptoms - and many see improvements after removing their implants.

Common complaints include:
👉 Being tired all. the. time.
👉 Facial swelling
👉 Achy joints or muscles
👉 Brain fog or trouble concentrating
👉 Skin rashes
👉 Weight gain
👉 Digestive problems
👉 Hair thinning
👉 Autoimmune-like flare-ups

Not fun. And while every person reacts differently, here are a few theories that help explain what might be going on.

Your Immune System Never Gets to Relax:
Implants are foreign objects. Your body knows it, and attacks, trying to protect you. This constant, low-grade inflammation, spirals into bigger symptoms if it goes on long enough.

Silicone & Metals Can Irritate Sensitive Systems:
Even saline implants have silicone shells, and over time tiny amounts can migrate out. Add in trace metals from manufacturing, and some bodies react more strongly than others. And if one leaks? Literal mold can form. Just look up "infected breast implants" and you will immediately cringe.

Biofilms Love to Set Up Camp:
We always address biofilms with our gut healing patients. Anytime something artificial is put in the body, biofilms form. Biofilms don’t cause the kind of infections that send you to the ER. Instead, they create a slow, smoldering inflammation that can spread beyond the implant or filler site. Biofilms require up to 5,000x the antibiotic dose to break them open! Add in chronic low grade infection, immune dysregulation, and stress on the adrenals, and you have a mess.

When it comes to implants, your body forms a capsule around them—that’s normal. But bacteria inhabit that space and create biofilms, driving all of the issues mentioned above.

Cosmetic Fillers: Small Injections, Big Ripple Effects:
I used to inject cosmetic fillers, and loved it! The creative and artsy side of me thrived. But after diving into Functional Medicine, you couldn't pay me enough to ever inject them into someone again. They can interact with your body in ways most people never consider.

Random Swelling or Lumps Later On:
Some people develop delayed reactions—weeks, months, or even years afterward. These flare-ups might show up after an illness, dental work, stress, or anything that fires up the immune system.

Yep, Biofilms Can Form in Fillers Too:
Remember how I said if anything foreign is put in the body it forms a biofilm on it? Fillers are no exception. This can lead to recurring swelling, chronic infection and inflammation, or little nodules that seem to “mysteriously” appear.

Your Lymphatic System Doesn't Love It:
Fillers sit right in your facial tissues - aka the same areas where lymphatic drainage is crucial. Your lymphatic system is basically your body’s drain and detox network. When it gets overloaded—whether from inflammation, toxins, or foreign materials—you feel it.

When things get congested, you may notice:
👉 Swollen lymph nodes
👉 Puffiness in the face
👉 Stubborn dark circles
👉 Brain fog
👉 Fatigue
👉 Breast tenderness
👉 Facial swelling
👉 Sinus pressure and congestion

Supporting lymph flow becomes really important for anyone with implants or fillers, especially if symptoms show up.

"I have implants and filler, what do I do?"
We look at the whole picture - not just the symptoms.

A typical evaluation might include: a deep dive into your symptom history, testing of immune and inflammation markers, gut and microbiome testing, hormone and adrenal assessments, assessment of detox and lymphatic function, and coordination with surgeons who specialize in explant or corrective work.

No cookie-cutter plans with us - your body gets a personalized roadmap to healing.

Bottom Line:
There’s nothing wrong with wanting to look and feel your best. But it’s important to know the whole story when it comes to implants and fillers - and to pay attention if your body starts sending signals. Remember that it whispers before it screams.

If you’ve had cosmetic procedures and now you’re dealing with symptoms that don’t quite add up, you’re not alone. Our functional medicine approach can help uncover what’s going on and guide you to feeling like yourself again! 🩵

11/01/2025

A Note From Our Founder:

November 1st marks six years of NFM. And year six was a big one. We moved to our brand new location. Expanded our team. Brought on new healing services. And my husband and I welcomed our fourth baby girl.

This year also brought new challenges mentally for me. With a growing business and a growing family, my heart is constantly pulled. Walking alongside my patients on their journey to health is such an honor. But nothing brings me more joy than being a mommy. And the sacrifices it takes to manage it all, are too numerous to count.

And yet I’m still so grateful. Since opening in 2019, we’ve had four moves to new spaces. Gone from myself as the only employee, to 11. Welcomed patients from several different states. Been a featured speaker on some big stages. And elevated ourselves to a premier healing center.

When it all feels like too much, I cling to a verse that brings me peace—“From everyone who has been given much, much will be demanded; and from the one who has been entrusted with much, much more will be asked.” Luke 12:48

I’ve been blessed with so much. NFM is what it is because I stand on the shoulders of giants. This journey has been nothing short of divinely inspired. The mentors in my life at the perfect times. A team that feels like family. And the beautiful unfolding of the entire journey itself.

Cheers to a wonderful year, and undoubtably, another exciting one ahead!

In Health,
Keri 🤍

10/29/2025

Urine Hormone Testing and Key Breast Cancer Clues 🔎

Let us start by saying, awareness for breast cancer isn't pink. It's properly testing your hormones and assessing your risk factors. Proper testing means using urine. Not saliva. Not blood.

When you test hormones using urine, you gain insight into their metabolism. And how you metabolize estrogen can influence how it affects your cells, the symptoms you experience, and overall vitality. One pathway in particular — the 4-hydroxylation (4-OH) pathway — has drawn attention for its potential link to breast cancer risk.

🩵 What Is the 4-OH Pathway?

When estrogens like estradiol are broken down in the liver, enzymes (especially CYP1B1) can convert them into 4-hydroxyestrone and 4-hydroxyestradiol. These compounds can be further oxidized into quinones, reactive molecules that can bind to DNA and cause mutations. Over time, this kind of DNA damage may contribute to cancer development — particularly in estrogen-sensitive tissues like the breast.

🩵 What the Research Shows

👉 Studies have found that higher levels of 4-OH estrogen metabolites — or a higher ratio of 4-OH to other estrogen forms — are associated with increased breast cancer risk, especially in postmenopausal women.
👉 In contrast, metabolites from the 2-hydroxylation pathway seem to be protective.
👉 Lab experiments back this up: 4-OH metabolites can damage DNA and transform normal breast cells into malignant ones.

🩵 Why It Matters

I tell my patients all the time--"Based on your symptoms, I can reasonably estimate the amount of each hormone you have. I don't need a test for that. I need to know HOW it is getting out of the body. That's where the healing happens."
Understanding the 4-OH pathway helps explain why estrogen’s role in breast cancer isn’t just about how much estrogen you have, but also about how your body processes it.

Genetics, liver function, diet, and lifestyle can all influence this balance. And if you're not pooping every single day, forget the rest of this! None of it matters if you're not eliminating those estrogens in your stool.

🩵 Checks and Balances

I also always tell my patients that God designed us perfectly. He created some "checks and balances" in the estrogen metabolism pathways, to protect us. If an estrogen does traverse down the 4-OH pathway, it can be methylated.

This is why it's important to be taking methylated B vitamins and understanding the MTHFR mutation! If that estrogen still becomes a quinone, it can be detoxified with glutathione! But so many things deplete our glutathione levels daily, that most of us are not optimal. Our urine test checks this, and we address it if necessary. That's why I love to say "test, don't guess."

🩵 The Bottom Line

If you are concerned about your hormones, breast cancer risk, and optimal health. Work with a team like ours. It is imperative to understand the complexity of hormones and the impact on your health. But also remember, hormones are one piece of the puzzle. You need to look at the entire picture. Only addressing hormones will lead to a bigger mess!

10/22/2025

Did you know that everyday products like plastic bottles, skincare, makeup, and even receipts can contain xenoestrogens - synthetic compounds that mimic estrogen in the body? Especially in breast tissue.

These hormone disruptors can interfere with your endocrine system, and growing research suggests a potential link between long-term exposure to xenoestrogens and an increased risk of breast cancer.

Over time, accumulation of xenoestrogens can cause:
👉 Increased estrogenic activity in breast tissue
👉 Altered gene expression related to cell cycle regulation
👉 Epigenetic changes that may promote tumor growth
👉 Elevated risk of hormone receptor-positive breast cancer

Examples of xenoestrogens include:
👉 Bisphenol A (BPA): Found in plastics & food linings
👉 Parabens: Common in cosmetics and lotions
👉 Phthalates: Hidden in synthetic fragrances
👉 DDT & other pesticides: Sprayed on fields environmentally

Make small swaps that make a big difference!
🩵 Choose glass or stainless steel containers
🩵 Go fragrance-free -- no more candles!
🩵 Opt for organic produce when possible
🩵 Swap your personal care products for lines like our OSEA and Jane Iredale

When you know better, you do better.

Address

1915 N Webb Road, Suite A
Grand Island, NE
68803

Opening Hours

Monday	9am - 5pm
Tuesday	9am - 5pm
Wednesday	9am - 5pm
Thursday	9am - 5pm

Website

http://www.nefunctionalmedicine.com/

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Nebraska Functional Medicine - Coming November 1, 2019

Functional Medicine determines how and why illness occurs and restores health by addressing the root causes of disease for each individual.

The Functional Medicine model is an individualized, patient-centered, science-based approach that empowers patients and practitioners to work together to address the underlying causes of disease and promote optimal wellness. It requires a detailed understanding of each patient’s genetic, biochemical, and lifestyle factors and leverages that data to direct personalized treatment plans that lead to improved patient outcomes. By addressing root cause, rather than symptoms, practitioners become oriented to identifying the complexity of disease. They may find one condition has many different causes and, likewise, one cause may result in many different conditions. As a result, Functional Medicine treatment targets the specific manifestations of disease in each individual.

Keri Anania is a board-certified Physician Assistant. She earned her Masters of Science in Physician Assistant Studies from the University of South Dakota. Prior to opening Nebraska Functional Medicine, she witnessed the "one size fits all" approach of conventional medicine, continually fail with her patients.