03/12/2026
GLP-1s have reshaped the world of chronic disease management, particularly diabetes and obesity, and it does not look like this is going to slow down anytime soon. With oral versions being released this year, demand for these drugs could be higher than ever.
As you discuss the benefits and drawbacks of GLP-1s with your patients, be sure to drive home these important points:
• Compounded GLP-1s from telehealth providers are not regulated and come with their own risks. Physicians should be personalizing treatment plans by evaluating medical history, health conditions, and potential risks. The lack of personalized medical supervision can be a risk to patients, especially those with comorbidities.
• GLP-1s help reduce appetite, support steady weight loss, and improve blood sugar control, but they are not a quick fix. They are potentially long-term treatments.
• Beware of potential polypharmacy situations in your patients over time. Weight loss may mean other medications, such as diabetes and blood pressure drugs, may need to be reduced for safety.
• For women of childbearing age, GLP-1s can increase fertility. Appropriate contraception should be discussed and prescribed.
For more on trends in GLP-1s, check out this recent Becker's piece: https://bit.ly/4cjQLXq