Indiana Alzheimer's Disease Research Center

12/24/2025

IU School of Medicine's Alyssa Swick shares some of the most common toy-related injuries or safety issues during the holiday season.

12/18/2025

Myth:
Dementia only affects people over 65.

Fact:
Although age is the greatest risk factor, dementia can also develop in people in their 40s or 50s. This is often called younger-onset or early-onset dementia and represents a smaller but significant portion of overall dementia cases.

In younger individuals, early symptoms are sometimes mistaken for stress, burnout, or depression, which can delay accurate diagnosis, care, and support.

Increasing awareness of younger-onset dementia supports earlier recognition of symptoms and stronger resources for both individuals and their families.

CLARiTI studies the brain health of people aged 50 or older to look for early signs of changes in brain health.

12/18/2025

A new partnership between Indiana University and Eli Lilly and Company will expand access to clinical trials and innovative treatments across Indiana. The five-year agreement strengthens Alzheimer’s research, enhances clinical trial innovation and supports the next generation of life sciences talent.

12/09/2025

A message from Director Andrew Saykin describing what the IADRC is and the work being done here by many researchers with the goal of treating and eventually preventing Alzheimer's Disease.

Watch the full video: https://www.youtube.com/watch?v=mHrRqYmcyy4

12/03/2025

RESEARCH UPDATE:

Research from Taeho Jo, PhD and Eun Hye Lee, PhD from the IADRC was recently published in Briefings in Bioinformatics, one of the top-tier journals in the bioinformatics field.

The paper presents a new method for assessing the reliability of AI predictions through uncertainty quantification. Using genomic data from 1,055 Alzheimer's disease patients and healthy controls, our researchers demonstrated that incorporating our method into predictions improved performance by 14% over state-of-the-art AI methods.

This method provides clinicians with objective measures to evaluate how much they can trust AI results when making patient care decisions.

Read the publication here:

Abstract. Alzheimer’s disease (AD) has complex genetic factors that make accurate prediction from genomic data challenging. Current methods lack confidence

12/03/2025

One of the many partnerships we have at the IADRC is with The Good Life.

The Good Life’s mission is to combat the public health crisis with dementia, heart disease and diabetes that disproportionately affects Black and Latin Americans. We provide classes and resources that honor our elders, support adults, and empower our youth for a healthier tomorrow; one filled with vitality and dignity for all.

Learn more:

Lead The Good Life with free interactive online classes Our programs support the healthy development and personal growth of Black and Latin Americans through a shared online positive experience that celebrates health, well-being and personal growth.  Enroll now How it works *All Classes are Free! N...

12/02/2025

On this , IADRC Director Andy Saykin is happy to share a message about how giving to our center helps.

Learn more about our center by watching the whole video here: https://www.youtube.com/watch?v=8PLBWn1dcOM

11/30/2025

“We are really trying to arrest this disease and ultimately prevent it. Your support enables the research that’s groundbreaking.” - Director Andy Saykin

This Tuesday, Dec. 2 is a global day dedicated to giving back. We have put together a short video explaining what giving does for our center.

Gifts to the Indiana Alzheimer’s Disease Research Center (IADRC) at the Indiana University School of Medicine support both critical research and educational ...

11/25/2025

New research from the IADRC published in Alzheimer’s & Dementia confirms that a short, 15-item "MIND diet screener" is a valid and effective way to measure how well someone is eating for brain health.

INTRODUCTION Higher adherence to the Mediterranean-DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay (MIND) diet has been associated with reduced Alzheimer's di...

11/20/2025

Dementia is not a single disease. It is an umbrella term for a group of conditions that affect memory, thinking, and daily function.

Under this umbrella are several types, including:
Alzheimer’s disease (the most common form), Vascular dementia, Frontotemporal dementia, Early-onset dementia, and others

Each type of dementia has different causes and symptoms, but all involve changes in how the brain works.

According to the Alzheimer’s Association, dementia describes a set of symptoms that interfere with daily life, often caused by brain cell damage that affects communication between cells.

11/20/2025

We loved having you! If anyone is interested in seeing Kevin and Kelly's speech or any other speech from the Martin Symposium, visit: youtube.com/playlist?list=PLflFTfLTVMWXfZ07iCX9Ag56SwRixPK5m&si=LkvmtN9iSUHi-6z8

11/14/2025

We were so delighted to have Monica Parker, MD, join us last Friday for the Martin Family Alzheimer's Disease Caregiver Symposium! If you missed her lecture or any other part of the event, you can now view the speeches here: https://bit.ly/4oHksFd