IU Simon Comprehensive Cancer Center

IU Simon Comprehensive Cancer Center Indiana's only NCI-designated comprehensive cancer center | A leader in cancer research To learn more, visit www.cancer.iu.edu.

The Indiana University Melvin and Bren Simon Comprehensive Cancer Center is Indiana’s only NCI-designated comprehensive cancer center and a member of the National Comprehensive Cancer Network. Based at Indiana University, we focus on cancer research, education and clinical trials—not patient care. Our researchers and physician–scientists are discovering how cancer works, developing new therapies, and training the next generation of cancer researchers. While our healthcare partners provide treatment, we lead the research that fuels tomorrow’s cures. To learn about our patient care partner, IU Health, visit www.iuhealth.org.

What if isolating stem cells for research and future therapies could be simpler and easier on the cells themselves?Scien...
12/12/2025

What if isolating stem cells for research and future therapies could be simpler and easier on the cells themselves?

Scientists at the IU Simon Comprehensive Cancer Center tested a new device that may do just that. The study found that the technology can isolate CD34+ stem cells—vital for treatments like stem cell transplants for leukemia and lymphoma—while putting less stress on the cells.

It could help support stronger research and future clinical applications. Learn more: https://ow.ly/W4Ks50XGWvv.

A new technology used for isolating stem cells could improve cancer research. 

Congratulations to the cancer center's Mark R. Kelley, PhD, for being named a 2025 fellow of the  National Academy of In...
12/11/2025

Congratulations to the cancer center's Mark R. Kelley, PhD, for being named a 2025 fellow of the National Academy of Inventors for his many contributions in pediatrics and cancer research. This prestigious honor recognizes his exceptional achievements as an inventor and his significant impact on the innovation ecosystem, economic development, and society.

Learn more: https://ow.ly/8llU50XHt7Z.

12/10/2025

A powerful moment for lung cancer advocacy in Indiana.

The 5th Annual End Lung Cancer Now Gathering brought together advocates, researchers, clinicians, and community partners who share one goal: reducing lung cancer deaths through prevention, early detection, and research. This event is a reminder of what’s possible when a community stands united.

Watch the recap and see the impact of this year’s gathering.

Every great team knows how to make a game plan—and ours is saving lives. At the IU Simon Comprehensive Cancer Center, sc...
12/09/2025

Every great team knows how to make a game plan—and ours is saving lives.

At the IU Simon Comprehensive Cancer Center, scientists and physicians work side by side to find new ways to detect cancer earlier, develop targeted treatments, and bring hope to more patients across Indiana and beyond.

From the lab bench to the basketball court, Hoosiers never back down from a challenge.

This season, and every season, it’s IU vs Cancer.

Learn more about how IU takes on cancer: https://ow.ly/XLQy50XnMJO.

What if we could stop one of the fastest-spreading breast cancers from gaining traction?New research co-led by an IU Sim...
12/04/2025

What if we could stop one of the fastest-spreading breast cancers from gaining traction?

New research co-led by an IU Simon Comprehensive Cancer Center and Indiana University School of Medicine researcher offers encouraging insight. In early studies, the drug candidate Ifetroban kept triple-negative breast cancer cells from sticking to platelets in mouse and zebrafish models. This prevented the disease from spreading to other organs.

Triple-negative breast cancer is especially tough to treat because it doesn’t use common breast cancer biomarkers. That limits treatment options and often leads to chemotherapy.

This discovery sheds light on a possible new way to contain the disease.

Learn more: https://ow.ly/pNzz50XA61E.

Ifetroban has shown early promise against triple-negative breast cancer. 

Access to lung cancer screening shouldn’t depend on your address. Yet many Hoosiers—especially in rural areas—still stru...
12/03/2025

Access to lung cancer screening shouldn’t depend on your address. Yet many Hoosiers—especially in rural areas—still struggle to reach the care they need. That’s why our team is expanding screening statewide with Indiana’s first and only mobile lung screening program, now visiting dozens of counties.

Screening numbers continue to rise, and tools like artificial intelligence and biomarkers are helping us spot signs of lung cancer earlier, when treatment has the best chance of success.

See how we’re bringing screening closer to home and strengthening early detection efforts:
https://ow.ly/Fu5550XAVoK.

IU School of Medicine is leading efforts to save Hoosier lives through new screening technologies for multi-cancer detection.For more than a century, Indiana...

We’re honored to have earned a Merit Award in the 2025 Digital Health Awards in the Science Storytelling and Website Red...
12/02/2025

We’re honored to have earned a Merit Award in the 2025 Digital Health Awards in the Science Storytelling and Website Redesign category.

This award reflects our dedication to sharing impactful stories of discovery, innovation, and collaboration in cancer research through the cancer center’s website.

A special thanks to our communications and information technology teams for their creativity, passion, and commitment to connecting people with science that makes a difference.

Discover our award-winning site at https://ow.ly/3VnP50Xt9XQ.

IU’s cancer research team doesn’t just play defense—we lead the offense. From developing the cure for testicular cancer ...
11/25/2025

IU’s cancer research team doesn’t just play defense—we lead the offense.

From developing the cure for testicular cancer to launching Indiana’s first mobile lung screening program, IU researchers have been changing the game for more than 30 years.

Inside the IU Simon Comprehensive Cancer Center, specialized teams focus on breast and lung cancer, immunotherapy, global oncology, and more, all working toward one goal: beating cancer.

Together we’re one team: IU vs. Cancer.

Learn more about how IU takes on cancer: https://ow.ly/9VXA50XnMIS.

11/21/2025

Are you curious about your cancer risk? Or wondering what your family history means for your health?

Join Nawal Kassem, MD, and certified genetic counselor Cindy Hunter, MS, LCGC, for a conversation on genetics, cancer risk, and how genetic testing may help people understand and manage their risk.

IU Simon Comprehensive Cancer Center is tackling lung cancer from every angle—enhancing prevention, improving early dete...
11/20/2025

IU Simon Comprehensive Cancer Center is tackling lung cancer from every angle—enhancing prevention, improving early detection, and developing personalized treatments to change the standard of care.

With lung cancer remaining the leading cause of cancer deaths in the United States, researchers at IU are working tirelessly to improve outcomes. Our Tom and Julie Wood Center for Lung Cancer Research is helping expand efforts in basic science, drug development, early-phase clinical trials, and precision genomics.

Learn more about how we are helping drive progress and how you can make a difference in the fight against lung cancer: https://ow.ly/HxRL50WUJuN.

Know the numbers. Know your risk. Lung cancer is the leading cause of cancer death, yet many people don’t realize they’r...
11/18/2025

Know the numbers. Know your risk. Lung cancer is the leading cause of cancer death, yet many people don’t realize they’re at risk. See the stats and take charge of your lung health. Together, we can .

The world's only healthy breast tissue bank—right here in Indiana—is expanding its impact.The Susan G. Komen Tissue Bank...
11/17/2025

The world's only healthy breast tissue bank—right here in Indiana—is expanding its impact.

The Susan G. Komen Tissue Bank at the IU Simon Comprehensive Cancer Center received a two-year, $750,000 grant from Susan G. Komen to support breast cancer research.

Since 2007, more than 5,600 women have donated healthy breast tissue to help scientists understand how breast cancer develops—and how to stop it before it starts.

Learn more about how IU researchers are transforming breast cancer research: https://ow.ly/Jvhq50XqCNy.

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535 Barnhill Drive
Indianapolis, IN
46202

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Our Story

The Indiana University Melvin and Bren Simon Comprehensive Cancer Center is Indiana’s only National Cancer Institute (NCI)-designated Comprehensive Cancer Center and one of only 51 in the nation. At the IU Simon Cancer Center, more than 200 scientists conduct research from four different programs. The goals of those programs range from understanding the molecular changes that cause cancer to developing targeted therapies to prevent and treat cancer. Through our partnership with Indiana University Health, cancer patients benefit from the scientific discoveries made at the IU Simon Cancer Center.