enVVeno Medical

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United States
Irvine, CA
enVVeno Medical

ABOUT THE TRIAL: What is the SAVVE Study? What is the VenoValve Procedure? How long is the SAVVE study? It is important to follow all post-procedure instructions.

We are a clinical-stage medical device company focused on the advancement of innovative bioprosthetic (tissue-based) solutions to improve the standard of care for the treatment of venous disease. Chronic Venous Insufficiency (CVI) occurs when the valves inside the veins of your leg do not function properly, causing blood to flow backward and pool in the lower leg, leading to elevated venous pressure inside the leg veins. The purpose of the SAVVE study is to determine whether the VenoValve® is a safe and effective treatment for patients with severe, deep venous CVI. The VenoValve is surgically implanted into a vein via a 5 to 6-inch incision in the upper thigh. The procedure should take less than an hour and the patient will receive general or regional anesthesia. After the VenoValve procedure, the patient will stay in the hospital for one night for patient comfort. The patient will be asked to see their doctor 7 days, 30 days, 90 days, 180 days, and 365 days after the VenoValve procedure. The VenoValve is designed to be a permanent implant and the patient should continue to see their doctor once a year for at least the next 4 years. FIRST-IN-HUMAN STUDY: Am I the first patient to receive a VenoValve? Eleven patients have already received the VenoValve as part of a small clinical trial. Safety incidences were minor, the disease severity (VCSS scores) improved an average of 56%, and pain (VAS scores) improved an average of 76%, compared to pre-VenoValve levels. The patients also experienced a significant improvement in their quality of life and were able to resume pre-CVI activities. The VenoValve stopped working after one patient stopped taking their prescribed medication.

03/30/2026

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03/27/2026

enVVeno Medical Reports Full Year 2025 Financial Results and Highlights Strategic Advancement of enVVe® System

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03/16/2026

Many patients with chronic venous disease still face limited treatment options and persistent symptoms.

At , we’re working to address these unmet needs and raise the standard of care for venous disease.

03/06/2026

Setting New Standards for Venous Care.

At enVVeno Medical, we’re advancing innovative solutions designed to improve outcomes and elevate care for patients living with venous disease.

Learn more: https://bit.ly/3E2yn1W

02/24/2026

For patients with chronic venous disease, everyday activities like standing, walking and sleeping can be significant challenges.

enVVeno Medical is developing first-in-class medical devices to improve patients’ lives and help make these daily moments simple again.

02/19/2026

We are a late clinical-stage medical device company focused on the advancement of innovative bioprosthetic (tissue-based) solutions to improve the standard of care for the treatment of venous disease

02/13/2026

3.5 Million patients continue to face debilitating challenges living with chronic venous disease due to limited treatment options.

At enVVeno, we are committed to advancing innovation to help change that.

02/05/2026

02/04/2026

enVVeno Medical Regains Compliance with Nasdaq Minimum Bid Price Requirement

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01/23/2026

We are working to develop medical solutions that may help restore mobility, comfort and confidence for people living with venous disease.

Learn more about our team here: https://bit.ly/3xSC1bS

01/16/2026

: Chronic Venous Disease is the most prevalent chronic disease in the U.S., impacting an estimated 175 million adults. CVD includes a range of venous conditions, with Chronic Venous Insufficiency (CVI) as a major subset caused by increased venous pressure from malfunctioning leg vein valves.

01/15/2026

enVVeno Medical Announces Reverse Stock Split

https://bit.ly/3Zj22iE

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Irvine, CA

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https://envveno.com/

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