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Monday 9am - 5:30pm Tuesday 9am - 5:30pm Wednesday 9am - 5:30pm Thursday 9am - 5:30pm Friday 9am - 5:30pm

Total Dermatology

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United States
Irvine, CA
Total Dermatology

Nissan Pilest, M.D. is a board certified dermatologist dedicated to the art of aesthetic dermatology. Dr. Pilest is a master level injection and laser physician.

He has developed a national reputation with his dermatology practice, treating both medical and cosmetic patients, beginning in 1979. is a Board-Certified Dermatologist with over 38 years experience in Corrective, Cosmetic, and Surgical Dermatology. He is a training physician for Fraxel CO2 Repair Laser, Botox, Juvederm, Restylane, Dysport, Candela Laser and Radiesse. Dr. Pilest is an Assistant Clinical Professor of Dermatology at the University of California Irvine; Fellow of the American Society for Laser Medicine and Surgery; Member, American Society of Dermatologic Surgery, Member California Society of Dermatology and Dermatologic Surgery; Member, California Medical Association; Member, Orange County Medical Association; Clinical Trials Physician for SDS Clinical Trials; Past President of the Dermatologic Society of Orange County; OC Top Doctor 2015 and 2016. Dr. Pilest’s practice, Total Dermatology, is recognized as one of Orange County’s most comprehensive laser centers.

02/06/2026

February is about healing, prevention, and renewal.
In honor of Cancer Awareness Month, we’re highlighting Fraxel Dual—an advanced laser treatment clinically shown to reduce precancerous lesions by up to 80%, while also improving sun damage, texture, fine lines, and overall skin health.

✨ February Fraxel Dual Special available
Because prevention is powerful—and confidence is priceless.

📅 Limited time | 📍Book your consultation today

02/05/2026

Cosmelan® is a professional depigmentation treatment designed to address melasma, sun damage, and uneven tone at its source, helping restore clarity and luminosity over time.

This is a carefully guided process, not a quick fix—because true results require expertise, consistency, and intention.
✨ Precision. Patience. Proven results.

📍 Consultation required.

01/27/2026

Same smooth… just lasts longer 😌✨
Meet Daxxify, the wrinkle relaxer that goes the distance.

Call our office today to see if Daxxify is right for you.
949-727-3800

01/23/2026

From the ✏️ pencil-thin brows of the 90’s to the fluffy brows of today, eyebrow trends are forever changing, but permanent makeup is...well, permanent. If your eyebrow tattoos are no longer your style, our laser can remove old ink and restore your brows to their natural state! 💥

When it comes to laser removal, the ink used for permanent makeup can be more unpredictable than traditional tattoo ink, at times resulting in tattoos turning a different color, like green. 🟩😱 It’s important to laser permanent makeup with caution, with virtually all cases starting first with a test spot so Dr. Pilest may determine how the tattoo will respond.

01/22/2026

Last night, Dr. Pilest attended ‘s 2026 Top Doctors event as both a guest and an honoree! 🩺🥼🏅

Each year, Orange Coast Magazine highlights a select group of “Physicians of Excellence,” as chosen by the Orange County Medical Association. These medical professionals are chosen based on their exhibited knowledge and skills, in addition to their commitment to their patients and the community of Orange County. Congratulations to Dr. Pilest and all of his fellow honorees! ✨

01/15/2026

Now offering PRF EZ Gel, an all-natural alternative to traditional dermal fillers that uses your body’s own healing power to restore volume, improve texture, and enhance glow 🌿

✔ 100% natural
✔ No chemicals or additives
✔ Improves skin quality + volume
✔ Stimulates collagen & elastin
✔ Ideal for under-eyes, cheeks, smile lines & more

Think subtle, refreshed, and you — just elevated ✨
Perfect for patients looking for a more natural approach to rejuvenation.

📞 Call us or DM to see if PRF EZ Gel is right for you

01/13/2026

January is prime treatment time ✨
We’re kicking off the year with January specials AND surprise flash offers dropped today ⚡️
Limited-time deals, major glow potential.

📩 DM or call ☎️ 949-727-3800 to snag your spot

01/05/2026

Some transformations shift a patient’s entire energy—and those are our absolute favorites! 🤩

Anyone familiar with melasma, a common skin condition that causes stubborn brown patches, knows just how frustrating it can be. Our Cosmelan peel continues to be our number one 🥇 treatment for tackling melasma, delivering incredible results in patients of all skin types. You can see here that our patient has a glow in her “after” that’s not only apparent in her complexion, but one that shines from the inside out! ✨

Don’t let dull skin hold you back in the new year. We offer special prices for Cosmelan, the BRAND NEW peptide-powered VI Peels, as well as all of our other chemical peels every Monday! 🗓️

12/31/2025

Wrapping up a year full of glow-ups, growth, and grateful hearts ✨
Thank you for being part of our journey see you next year!

12/30/2025

✨ Clear & Brilliant season is HERE ✨

Because your skin deserves to sparkle all year long.

🎄 December Special 🎄
💎 Clear & Brilliant Laser
👉 Buy a package of 3, get 1 FREE
💰 Package of 3: $2,000

Brighter. Smoother. That effortless glow everyone asks about.

📅 Limited-time December only book now!
☎️ 949-727-3800

Address

16100 Sand Canyon Avenue, Ste 190
Irvine, CA
92618

Opening Hours

Monday	9am - 5:30pm
Tuesday	9am - 5:30pm
Wednesday	9am - 5:30pm
Thursday	9am - 5:30pm
Friday	9am - 5:30pm

Telephone

+19497273800

Website

http://www.totaldermatology.com/

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