Reeve Irvine Research Center (UCI)

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Reeve Irvine Research Center (UCI)

The RIRC is devoted to the study of repair, regeneration, and recovery of function after spinal cord injury.

The Reeve-Irvine Research Center (RIRC) is a basic science research facility devoted to the study of repair, regeneration, and recovery of function after spinal cord injury. We depend greatly on your generous donations, which help enable our research. Your contributions will be used to advance research that is targeted to new treatments for spinal cord injury.

04/09/2026

We are thrilled to announce this year's MTS Program: Join us for the 2026 Meet the Scientists, hosted by the Reeve-Irvine Research Center (RIRC), as we welcome Dr. Monica A. Perez, PT, PhD, a leading expert in spinal cord injury recovery and principal investigator of the NVG-291 clinical trial. This is a unique opportunity to hear directly from the scientist behind the work, gain insight into emerging findings, and engage in meaningful conversation with the research community. A brief update on clinical trials will be given by RIRC Founding Director, Dr. Oswald Steward, PhD.
Keep a look out for a follow up post for RSVPs and more exciting details!

02/19/2026

A new Roman Reed bill for SCI research funding is introduced to the legislature!

Roman Reed has done it again! Based on strong advocacy by Roman and others, California Assembly Member Alex Lee (District 24) has introduced AB2228 which would be a $1million appropriation to support spinal cord injury research in California.

Way to go Roman!!!

And a million thanks to Assemblyman Lee!!!

11/28/2025

Thank you to EVERYONE who came out to the Plymouth Rock ‘n Run this morning at Yorba Regional Park! 🦃🏃‍♀️🏃‍♂️✨
This year was a huge success — the 5K completely sold out, and the remaining races had only a handful of spots left. Your energy, smiles, and commitment made this Thanksgiving morning truly special.
We are especially grateful because a portion of the proceeds directly supports the Reeve-Irvine Research Center, helping fund critical research in neural repair, regeneration, and recovery of function after spinal cord injury. Your participation genuinely helps move this important work forward.
If you snapped any great photos from today’s run, we’d love to feature them! 📸
Send us your images via DM.
Thank you all for showing up, giving back, and being part of something so meaningful. Happy Thanksgiving! 🍽

11/25/2025

We look forward to seeing you all at the 2025 Plymouth Rock n Run Thanksgiving Morning event! Direct link for details on race-day schedules, award categories and bib pick up options: https://runsignup.com/Race/Info/CA/Anaheim/PlymouthRocknRun Let's have some FUN!

08/10/2025

Another look at Oligodendrocyte Precursor Cell (OPC) transplants for SCI:

The company Lineage Cell Therapeutics has launched another clinical trial involving Oligodendrocyte Precursor Cell (OPC) transplants. RIRC followers will remember that this was the approach pioneered by Hans Keirstead 20 years ago that led to the original Geron trial, which was the first clinical trial of stem cell transplants for SCI funded by the California Institute for Regenerative Medicine. The purpose of this new clinical trial is to evaluate safety and performance of a new injection device. Of note, this trial will enroll participants with both acute and chronic injuries and treatment of an individual with a chronic injury has just been announced (below). Although the purpose of the trial is to evaluate the new injection device, the company will be carrying out functional assessments on all patients, to investigate any signals of efficacy.

The new trial is an exciting opportunity to learn more about surgical techniques for cell delivery into the injured spinal cord and the potential of OPC’s to enhance function.

Lineage Cell Therapeutics has treated the first-ever chronic Spinal Cord Injury patient with OPC1 in its DOSED study at UC San Diego Health.

To read more, use the link below:

https://investor.lineagecell.com/news-releases/news-release-details/lineage-announces-dosing-first-patient-new-clinical-study-opc1

04/26/2025

Meet the scientists happening now!

04/15/2025

We Welcome You To Our Annual Meet The Scientists Event - Join in the conversation and see how our labs are working to support the SCI community. - https://mailchi.mp/d13900bc8b16/join-our-annual-meet-the-scientists-event

04/10/2025

We’re excited to announce this year’s Meet the Scientists event at the Reeve-Irvine Research Center at UCI! We’ve got an amazing event planned with incredible guests, demos and a Q&A session—hope to see you on April 26th!

03/29/2025

RIRC Meet the Scientists Saturday April 26. Save the date.
Updates and discussion of ongoing clinical trials led by Sam Maddox.
Demo and discussion of new studies on seated balance by Dr. Maya Hatch.
Demo of next gen ReWalk.
More details to come.

01/09/2025

It is with great sadness that we report the passing of Professor Jerry Silver on January 7, 2025. Jerry was one of the true pioneers of the modern age of spinal cord injury research. His energy, enthusiasm, and extreme optimism brought hope to many who are living with spinal cord injury.

11/28/2024

A beautiful morning on the Plymouth Turkey Trot course!

Address

837 Health Sciences Road
Irvine, CA
92697

Website

https://www.reeve.uci.edu/

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