Leigh Erin Connealy, M.D.

Leigh Erin Connealy, M.D. Leigh Erin Connealy, M.D. is a prominent leader in the field of Integrative Medicine. Dr. Connealy began practicing medicine in 1986.

She is the Medical Director of Cancer Center for Healing and Center for New Medicine, and the author of The Cancer Revolution. Leigh Erin Connealy, MD attended the University of Texas School of Public Health, and then attended the University of Health Sciences Chicago Medical School. She completed her post-graduate training at the Harbor/UCLA Medical Center in Los Angeles, California. Dr. Connealy soon realized that conventional medicine had very limited returns and did not always improve the health of her patients. Her patients were hungry for alternative approaches for improving their health. This led her to study integrative and complementary therapies, and since then she has revolutionized the landscape of medicine. Dr. Connealy feels that we must treat the patient with the disease and not the disease of the patient. She has discovered that many factors contribute to the disease process; therefore, many modalities must be used to reverse it. Dr. Connealy treats the WHOLE person, and is open to all potential treatment possibilities. She has over twenty years of experience in finding the ‘root cause of an illness’, and has taken numerous advanced courses, including homeopathic, nutritional and lifestyle approaches, while studying disease, chronic illness, and cancer treatments. She has a true passion to change her patients’ lives, and give them their life back. In 1992, she founded the Center for New Medicine in Irvine, California, where she serves as Medical Director. Her practice is firmly based in the belief that strictly treating the health problems with medications does not find the root cause of the illness. The Center offers a vast array of services for men, women and children, including detoxification, holistic dentistry, nutrition, fitness and weight loss, cosmetic/laser treatment, pain management, allergy therapy, acupuncture, massage therapy, hyperbaric oxygen therapy, sleep disorders, and much more. We also provide specialized services in gynecology, natural fertility, menopause, hormone imbalances for all ages, healthy sexuality, healthy aging, and personalized preventive medicine. Some of the chronic conditions treated at the clinic include cancer, heart disease, diabetes, neurological and auto-immune disorders. Dr. Connealy writes and has been published in monthly health columns for "Coast" and "OC Health", Orange County based magazines and is published in "The Journal of the American Nutraceutical Association" (JANA), along with Healthy Aging Magazine. She is a frequent writer for Natural News. She is also a weekly co-host on Frank Jordan’s national radio show "Healthy, Wealthy and Wise" on Sirius/XM Channel 131 digital cable, KSPA 1510 AM, and WAVA 780. Dr. Connealy is a frequent guest speaker at professional organizations and on local cable television shows when highlighting health topics like KTBN or Know the Cause with Doug Kaufman airing across the country periodically. She has a weekly publication newsletter with Newport Natural Health and Eagle Publishing. To learn more about Leigh Erin Connealy, M.D. we invite you to visit www.centerfornewmedicine.com or www.perfectlyhealthy.com or www.connealymd.com or www.newportnaturalhealth.com.

6 Hughes • Suite 100 • Irvine • California • 92618 949.680.1880 • 949.680.1881 fax www.centerfornewmedicine.com • info@cfnmedicine.com

12/23/2025

Unfortunately glioblastoma, the most aggressive form of brain cancer, is becoming increasingly common.

In the U.S., it accounts for nearly 50% of all malignant brain tumors, and its incidence has been rising by about 1.4% per year in adults over age 65.

Glioblastoma develops from glial cells, specifically astrocytes, which normally provide structural and metabolic support to neurons. It is known for its quick progression, resistance to treatment, and poor prognosis.

Part of the reason why glioblastoma is so difficult to treat is because it doesn’t form as a single, well-defined mass.

It sends out microscopic extensions, weaving into healthy brain tissue, wrapping around blood vessels, and threading through delicate white matter. This infiltrative pattern makes it extremely difficult to remove the tumor entirely without risking damage to critical brain functions. Even when the majority is surgically removed, the cells can remain undetected and regrow.

Unlike many other cancers, glioblastoma typically stays within the brain. The skulls’s closed environment means there’s very little space for the tumor to grow, but as it expands, it can cause swelling, pressure, seizures, and a gradual decline in function – in the body’s most critical organ.

Some potential treatment options for glioblastoma:

1. Dietary changes
2. Thiamine
3. Niacinamide
4. Aspirin
5. High dose vitamin C IV (Brown, 2017)
6. Progesterone (Zhou et al., 2022)
7. Retinoic acid (Ying et al., 2014)

At the clinic, we want to explore every option that could help destabilize the tumor or support the surrounding brain. Some other options include:

- Dopamine
- Ivermectin or fenbendazole
- Thyroid hormones

None of these are a silver bullet, but layering therapies and restoring resilience in the brain’s own environment, can help to shift the brain’s terrain. 🧠🧠🧠

12/22/2025

The flu has been recently going around, so during this time, the body may need some extra immune support! Here are a few of my favorite products for when my family and I are feeling under the weather: ❄️

1. Camu Camu’s Vitamin C: contains pure, whole food vitamin C, decreases free radicals, oxidative stress, and inflammation. Vitamin C promotes a healthy immune response by facilitating immune cells to the site of infection, enhances phagocytosis, and allows cells to kill pathogens.

2. Reacted Zinc: Antioxidant and anti inflammatory agent, reduces duration and severity of colds, supports healthy function of immune cell, supports a healthy metabolism.

3. ColdCalm–Boiron: Homeopathic remedy, natural, non-drowsy, works at any stage of a cold, preservative free, contains natural remedies such as yellow jessamine, allium sepa, and apis mellifica, relieves all symptoms of a cold including headaches, cough, congestion, fever, inflammation, etc., and supports the body’s natural ability to heal.

4. Vitamin D3/K2: Vit D regulates immune cell function and mitigates the inflammation associated with the immune response. Deficiency is associated with increases all cause mortality and autoimmunity (PMID: 24922127). Supports bone & heart health by promoting healthy calcium absorption and preventing calcification of arteries.

5. Magnesium flakes (ancient minerals) for baths: Magnesium supports relaxation of the nervous system, muscle recovery, and sleep—critical during illness. Warm magnesium baths can help lower stress hormones, support circulation, and promote rest, which is when immune repair is most active.

I always prefer to use natural, nontoxic products that promote the body’s ability to fight infection, rather than suppress symptoms.

You can purchase all of these at / www.perfectly healthy.com 🤍❄️

12/19/2025

Today, there’s an intense focus on longevity—slowing aging, preventing disease, and preserving function for as long as possible. We’re sold endless supplements, potions, and protocols promising to keep our cells young. Some are useful, many are not. But one of the most overlooked drivers of longevity isn’t something you can buy—it’s how the body experiences energy, stress, and engagement with life.

Youthful physiology is defined by high metabolic rate, flexible stress responses, strong repair capacity, and curiosity-driven behavior. Aging, in many ways, is the gradual loss of these conditions.

A few of my favorite longevity “hacks”:
⁃ Eat like a child: Children eat when they’re hungry, stop when they’re full, and tend to eat smaller, more frequent meals. This keeps blood sugar stable, supports a higher metabolic rate, and prevents chronic cortisol and adrenaline release. In fact, children have metabolic rates up to ~50% higher than adults. With age, we often override hunger cues and disconnect from appetite signals—but those instincts are still accessible.
⁃ Choose food that genuinely tastes good to you (when it’s real food, not processed chemicals). Appetite and taste are regulatory signals. When food is unprocessed and nutrient-dense, preference often reflects need. There is no perfect diet for everyone—children intuitively adjust intake, and adults can relearn this skill.
⁃ Treat problems as challenges to overcome, not threats. Reframing stressors—whether a diagnosis, setback, or uncertainty—as obstacles to navigate rather than dangers to fear changes nervous system output. As we age, we face more challenges, but is it possible to interpret them as a game we can overcome?
⁃ Never stop playing. For kids, play is everything. It’s how they explore the world and how they problem solve. And this instinct doesn’t stop in childhood, we often just forget. The way we play changes. Tiger Woods plays golf, I play a doctor, and my son plays an economics wiz.

Continued in the comments 😊

12/17/2025

One of my fav meals ❤️🍔Healthy eating isn’t about fearing foods, but rather about paying attention to the details.

A burger can be a nutrient-dense meal. The difference comes down to the ingredients. Is the beef grassfed? Is it cooked in stable fats like butter or olive oil, or in industrial seed oils? Is the bun made from simple, traditional ingredients, or from a long list of additives? It’s all about the details!

12/16/2025

Fractionated chemotherapy refers to the administration of chemotherapy drugs in multiple smaller doses, rather than a single large dose. This approach allows for the delivery of chemotherapy over a longer period, with breaks in between each dose. The goal is to improve the effectiveness of treatment while minimizing toxicity and side effects.
The concept of fractionated chemotherapy is based on the idea that cancer cells have different sensitivities to chemotherapy drugs at different phases of their growth cycle. With smaller, more frequent doses, it is possible to target cancer cells at different stages of the cell cycle, increasing the overall effectiveness of treatment.

When insulin is administered alongside glucose and low-dose chemotherapy, it further sharpens the metabolic targeting of cancer cells.

Insulin is a powerful signal for nutrient uptake and growth. Many cancer cells overexpress insulin receptors and IGF-1 receptors. When insulin is given, it drives glucose transporters to the cell surface and dramatically increases glucose uptake. Because cancer cells are already biased toward glycolysis and hungry for sugar, they respond disproportionately to this signal compared to healthy cells.

This insulin-driven uptake does two things at once. First, it funnels glucose into tumor cells, pulling them into an active, fed metabolic state and pushing them out of quiescence. Cells that are metabolically “awake” and entering the cell cycle are more vulnerable to chemotherapy, even at lower doses. Second, insulin increases membrane permeability and intracellular trafficking, which can enhance the intracellular concentration of chemotherapeutic agents inside cancer cells relative to surrounding healthy tissue.

Continued in the comments…😄

12/16/2025

10 of my most controversial opinions: ❤️⬇️

- Cancer is primarily a metabolic and energetic disease, not a genetic one. Mutations are downstream from impaired cellular respiration, inflammation, and energy loss. Genes are not the ultimate determinants of your health. Lifestyle, environment, and diet play a much larger role in shaping health outcomes than genetic predisposition alone.

- Estrogen is a major driver of many cancers, especially breast cancer, and its role is consistently minimized. Estrogen promotes tissue growth, including the growth of cancer cells. Today many women are estrogen dominant. Higher estrogen exposure also helps explain why women are more affected by autoimmune diseases, conditions like endometriosis and fibroids, migraines, gallbladder disease, thyroid disorders, etc. Progesterone, thyroid function, and metabolic rate are highly protective against the effects of estrogen.

- Seed oils and excess polyunsaturated fats damage mitochondria and quietly drive modern disease.They are highly unstable, cause oxidative stress, suppress thyroid, and increase inflammation, cancer risk, and obesity. They are not “heart healthy.”

- Healthy sunlight exposure is protective, not harmful. Sunlight helps the body produce vitamin D and supports immune function. It is not the main cause of skin cancer. We were designed to live under the sun.

⁃ Meat, especially from well-raised animals, is a vital part of a healthy diet. Animals have been apart of the human diet for 3 million years. Animal proteins and fats offer essential nutrients that are difficult to obtain from plant-based diets alone.

- Many autoimmune diseases reflect low metabolism and hormonal imbalance, not an immune system “attacking itself.” Many autoimmune diseases reflect low metabolism and hormonal imbalance, not an immune system “attacking itself.” Estrogen amplifies immune activity and inflammation, while low thyroid function and inadequate progesterone reduce the body’s ability to regulate and resolve immune responses. Restoring thyroid and progesterone levels and reducing stress hormones can help to treat autoimmune conditions

Continued in the comments…🩺

12/15/2025

A lot of people think that health requires rare superfoods found in remote jungles or pricey powders with fancy labels. But I think the simpler, the better. Real health comes from familiar ingredients your body recognizes, things people ate hundreds of years ago.

For example, health smoothies often have almond milk, raw kale, chia seeds, vegan protein powder, and “detox” greens.

Those ingredients might look good on paper, but they’re often hard to digest and not actually that nourishing. Nut milks are low in protein and calcium. Raw greens can irritate the gut. Seeds are full of PUFAs. And “superfood” powders usually contain metals or fillers.

My version of a healthy smoothie:
✨ Whole milk or raw milk: for bioavailable calcium, protein, and fat-soluble vitamins
🍊 Ripe fruit or fresh orange juice: easy-to-digest carbs and antioxidants
💪 Collagen or gelatin: to support skin, joints, and the gut lining
🍯 A spoonful of honey or maple syrup: to fuel metabolism, not crash it
🥥 Coconut cream: for healthy saturated fats
🥚 Egg yolk: rich in choline, cholesterol, and vitamin A
🧂 Salt: or adrenal and electrolyte balance

Our bodies don’t need exotic berries or algae grown in remote jungles. It needs minerals, sugars your cells can use, fat-soluble vitamins, good salt, and food that supports digestion.

12/12/2025

3 things I tell my patients 🤍💪

12/12/2025

Thyroid cancer has risen sharply over the past several decades, and while improved imaging accounts for some of this increase, it doesn’t explain the full trend. The thyroid is a uniquely active gland, constantly exposed to high levels of oxygen, iodine, and rapid hormone synthesis. Under healthy conditions, this supports efficient metabolism and stable cell structure. But when the gland is under chronic stress—low thyroid function, inflammation, high estrogen exposure, or environmental toxins—its cells become more vulnerable to damage. They produce more reactive oxygen species, repair DNA less effectively, and gradually lose the structural cues that keep growth controlled. Some risk factors:

1.Persistent TSH stimulation: When thyroid hormone output is low, the pituitary increases TSH to push the gland harder. Over time, this acts as a growth signal, increasing the formation of nodules and raising the likelihood that abnormal cells will emerge.

2.Estrogen: Estrogen promotes swelling and abnormal cell proliferation within thyroid tissue, which helps explain the higher incidence in women and the growing concerns around endocrine-disrupting chemicals. Progesterone and sufficient thyroid hormone counteract these effects and support more stable cell behavior.

3. Radiation: A stressed, hypothyroid gland repairs radiation injury poorly.. Modern conditions, including high PUFA intake, chronic stress, and higher environmental toxin loads, further influence how well thyroid cells respond to any form of injury.

The rise in thyroid cancer reflects a shift toward a more stressed and unstable environment. Supporting healthy thyroid hormone levels, keeping TSH low, supplementing with progesterone, reducing PUFA intake, mitigating radiation exposure are all. Important steps for prevention and treatement. 🦋🦋🦋

12/12/2025

Thyroid cancer has risen sharply over the past several decades, and while improved imaging accounts for some of this increase, it doesn’t explain the full trend. The thyroid is a uniquely active gland, constantly exposed to high levels of oxygen, iodine, and rapid hormone synthesis. Under healthy conditions, this supports efficient metabolism and stable cell structure. But when the gland is under chronic stress—low thyroid function, inflammation, high estrogen exposure, or environmental toxins—its cells become more vulnerable to damage. They produce more reactive oxygen species, repair DNA less effectively, and gradually lose the structural cues that keep growth controlled. Some risk factors:

1.Persistent TSH stimulation: When thyroid hormone output is low, the pituitary increases TSH to push the gland harder. Over time, this acts as a growth signal, increasing the formation of nodules and raising the likelihood that abnormal cells will emerge.

2.Estrogen: Estrogen promotes swelling and abnormal cell proliferation within thyroid tissue, which helps explain the higher incidence in women and the growing concerns around endocrine-disrupting chemicals. Progesterone and sufficient thyroid hormone counteract these effects and support more stable cell behavior.

3. Radiation: A stressed, hypothyroid gland repairs radiation injury poorly.. Modern conditions, including high PUFA intake, chronic stress, and higher environmental toxin loads, further influence how well thyroid cells respond to any form of injury.

The rise in thyroid cancer reflects a shift toward a more stressed and unstable environment. Supporting healthy thyroid hormone levels, keeping TSH low, supplementing with progesterone, reducing PUFA intake, mitigating radiation exposure are all. Important steps for prevention and treatement.🦋🦋🦋

12/10/2025

An article published in BMJ Oncology states that from 1990 to 2019, new cancer incidences in patients younger than 50 years old have increased by nearly 80% worldwide. Unfortunately, it is becoming more common for people in their 20s and 30s to receive a cancer diagnosis.

Rising rates in young people suggest that something external must be contributing to cancer, as opposed to a genetic predisposition. Our genes are not fundamentally different from what they were in 1990. However, many changes have taken place in our environment. Industrial processes, changes to the food supply, chemical exposures and new technologies have separated us from nature. When we are out of alignment, for example, eating foods that were not designed for our bodies or living under artificial light, cells become dysfunctional. There are several environmental and dietary factors influencing cancer rates:

1. Lack of sunlight
2. Poor nutrition (nutrient deficiencies)
3. Hormone imbalances
4. Exposure to toxins
5. Exposure to radiation
6. Emotional stress and trauma

Focusing on emotional health, nutrient-dense diets, movement, and healthy sunlight exposure are all extremely important in preventing cancer development. These statistics, although alarming, suggest we do have the power to change outcomes by taking intentional action.

Zhao J, Xu L, Sun J, et alGlobal trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019BMJ Oncology 2023; 2:e000049. doi: 10.1136/bmjonc-2023-000049

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