NovaSterilis

NovaSterilis NovaSterilis uses supercritical CO2 solutions to promote safe, innovative products and improve lives.

NovaSterilis is the global leader in the development and manufacturing of supercritical carbon dioxide (scCO2) processes for biomaterials and medical devices, including the decellularization and sterilization of allograft and xenograft tissues. At its core, NovaSterilis is a team of scientists, engineers, and business people committed to meeting our customers' needs through problem-solving. Our mu

lti-disciplinary team of engineers, biochemists, and molecular and cellular biologists bring their broad and deep knowledge to every development challenge. We have the team, equipment, and processes readily available to provide scCO2 solutions that enable the implementation of manufacturing solutions that meet product safety requirements and performance and enable our partners to deliver safe, innovative products that advance patient healing and outcomes. With NovaSterilis you can count on a sterility assurance level 10-6, an environmentally friendly solution, shorter turnaround times, and more. Protect and differentiate your products with supercritical CO2.

04/29/2026

This video shows water incorporation into CO2 over time.

Supercritical CO2 sterilization is unique from other methods since the level of moisture is completely tunable.

While other sterilization modalities require either pre-conditioning steps or are limited by a product’s hydration content, the cycle parameters of scCO2 can be adjusted to fit the needs of each product.

Stay tuned for more videos and see how CO2 and interact!

  plays a major role in the quality and mechanical performance of  .Legacy modalities can risk collagen disruption, mech...
04/27/2026

plays a major role in the quality and mechanical performance of .

Legacy modalities can risk collagen disruption, mechanical degradation, and reduced biological performance.

Explore tissue sterilization strategies using : https://bit.ly/4k5NF9B

  involves multiple pathways, data requirements, and regulatory decision points.This resource is your guide to designing...
04/24/2026

involves multiple pathways, data requirements, and regulatory decision points.

This resource is your guide to designing a process that aligns with the utmost standards of safety, efficacy, and security.

Download now: https://bit.ly/45f6wrW

04/22/2026

Have you ever wondered how supercritical CO2 actually achieves sterilization?

This study investigates spore inactivation mechanisms using and peracetic acid.

The researchers performed a variety of experiments and utilized various analytical methods to gain insight into the mechanism of sterilization.

Read more: https://bit.ly/4pGPwFp

Overlooking   can derail product development. In this article, NovaSterilis CEO Tony Eisenhut emphasizes why integrating...
04/20/2026

Overlooking can derail product development.

In this article, NovaSterilis CEO Tony Eisenhut emphasizes why integrating strategies early in R&D is crucial. Read it here: https://bit.ly/3rZMCm1

This white paper evaluates   sterilization of amniotic fluid and cytokine preservation.Analysis shows conservation of th...
04/17/2026

This white paper evaluates sterilization of amniotic fluid and cytokine preservation.

Analysis shows conservation of the majority of proteins after processing.

It examines performance alongside the retention of native protein content. Read more: https://bit.ly/4c2gema

Packaging and   should be co-developed to ensure material compatibility and barrier integrity.Sterilization modality sel...
04/16/2026

Packaging and should be co-developed to ensure material compatibility and barrier integrity.

Sterilization modality selection directly influences packaging materials, batch sizes, and validation strategy.

Learn more about this interdependency and its impact on your device’s safety and performance:

Explore the interplay between medical device packaging and sterilization, including considerations to ensure device sterility and integrity.

It was great to be at SAWC Spring last week!     The team had a fantastic few days connecting with attendees and sharing...
04/15/2026

It was great to be at SAWC Spring last week!

The team had a fantastic few days connecting with attendees and sharing more about how NovaSterilis is supporting innovation in wound care.

It was also an honor to see the team recognized with an award for “Real skin, real insights: evaluating biodistribution wound healing of cell-free amniotic fluid with an ex vivo viable human skin model.”

Thank you to everyone who stopped by and engaged with our team!

This study evaluates   for adipose tissue delipidation and decellularization.Results show preserved ECM proteins, growth...
04/14/2026

This study evaluates for adipose tissue delipidation and decellularization.

Results show preserved ECM proteins, growth factors, and enhanced cell–material interactions.

This supports ’s use in bioactive coatings and soft tissue applications. Read more: https://bit.ly/493mpXi

  confirms process parameters achieve defined sterility assurance levels for each product.Method selection requires bala...
04/10/2026

confirms process parameters achieve defined sterility assurance levels for each product.

Method selection requires balancing microbial inactivation with material and functional constraints.

Discover validation strategies and their impact on safety and efficacy: https://bit.ly/3TQ8QD0

04/08/2026

Our new visualization capabilities allow us to observe flow dynamics, phase mixing, and the material’s response throughout the entire sterilization process.

This capability supports process optimization and informed material design through real data.

Take a look inside the vessel: https://bit.ly/4qZsI4H

Until now, bringing sterilization in-house for medical device companies has never been practical.But, the emergence of n...
04/06/2026

Until now, bringing sterilization in-house for medical device companies has never been practical.

But, the emergence of novel sterilization methods (like supercritical CO2) has completely changed this reality…

With these types of modalities, bringing sterilization in-house is not only possible, but it also makes perfect sense from a logistical AND economical point of view.

Supply chain constraints and regulatory pressure on traditional sterilization methods are further encouraging this migration towards novel methods.

Alternative modalities like can actually reduce turnaround time and lower entry barriers.

Learn more about this shift and its operational benefits: https://bit.ly/4bM5Yjh

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3109 North Triphammer Terrace
Lansing, NY
14882

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