NovaSterilis

12/29/2025

remains a limiting step for protein-based manufacturing.

GLP-1 and EGF denature under heat, radiation, and chemical sterilization.

This article evaluates process constraints for preserving protein structure and function using . Read more: https://bit.ly/4cypoa1

12/26/2025

As 2025 comes to a close, we’re reflecting on how far NovaSterilis has come,

starting with the commercialization of our terminal sterilization process,

all the way to having multiple medical devices cleared through the FDA and >500K surgeries completed worldwide.

This year has been one of continued innovation and collaboration!

12/25/2025

Happy Holidays from the NovaSterilis team! ✨

12/24/2025

Adopting new technology requires clear justification, both technical and financial.

Discover how material compatibility testing establishes feasibility,

while optimization studies refine parameters to ensure reproducibility:

Explore the role of compatibility testing and how the insights it provides inform decisions when considering new sterilization equipment.

12/23/2025

Preserving the mechanical and biological integrity of tissues remains

a central challenge in ACL reconstruction and regenerative medicine.

Data shows that irradiation-based methods compromise collagen structure and reduce functional performance,

while maintains biomechanical properties and key growth factors. https://bit.ly/4iFQFJ5

12/22/2025

NovaSterilis and Dr. Peter Setlow’s lab at UConn collaborated to explore the actual mechanism for scCO2 sterilization.

Check out the findings in this peer-reviewed journal article: : https://bit.ly/4pGPwFp

12/19/2025

Rising demand for allograft tissues is pushing methods to keep pace with more advanced processing and higher clinical expectations.

offers a path to maintain structural fidelity while addressing workflow and scalability needs.

Explore conversion challenges, emerging solutions, and pathways for gradual adoption:

Over the last decade, demand for allograft tissues has grown dramatically, making tissue sterilization a top priority for both surgeons and the patients who rely on them. While traditional sterilization methods have long served the tissue banking industry, innovation is accelerating, and with it, t...

12/18/2025

The time-lapse provides a clear view of how CO2:

-enters the chamber
-reaches its supercritical state
-holds at operating pressure and temperature
-depressurizes with characteristic expansion of elastomeric components

NovaSterilis has developed secondary processes to enhance the compatibility of elastomeric materials and mitigate the swelling that occurs under standard conditions.

Watch more videos on the progression of the cycle: https://bit.ly/4qZsI4H

12/17/2025

Validating processes requires reliable measurement of low-level PAA residuals.

™ enables high-throughput analysis with low-level ppm sensitivity, offering a practical tool for organizations collecting data for advanced material analysis.

Download the white paper here to explore further: https://bit.ly/4mbCOfH

12/16/2025

This article details the global considerations for manufacturers as ongoing compliance is driving companies to find alternatives to EtO.

is one alternative that is mentioned by name –

This technology is available to address the call for safer and more effective approaches.

The European Union has introduced a groundbreaking regulation aimed at ensuring sustainable product design, targeting the pervasive issues of industrial waste

12/15/2025

Effective depends on aligning SAL requirements with material constraints

through approaches such as overkill, bioburden, and combined BI/bioburden methods.

Discover how each validation strategy functions, where it applies,

and how to evaluate compatibility challenges: https://bit.ly/3TQ8QD0