NovaSterilis

NovaSterilis NovaSterilis uses supercritical CO2 solutions to promote safe, innovative products and improve lives.

NovaSterilis is the global leader in the development and manufacturing of supercritical carbon dioxide (scCO2) processes for biomaterials and medical devices, including the decellularization and sterilization of allograft and xenograft tissues. At its core, NovaSterilis is a team of scientists, engineers, and business people committed to meeting our customers' needs through problem-solving. Our multi-disciplinary team of engineers, biochemists, and molecular and cellular biologists bring their broad and deep knowledge to every development challenge. We have the team, equipment, and processes readily available to provide scCO2 solutions that enable the implementation of manufacturing solutions that meet product safety requirements and performance and enable our partners to deliver safe, innovative products that advance patient healing and outcomes. With NovaSterilis you can count on a sterility assurance level 10-6, an environmentally friendly solution, shorter turnaround times, and more. Protect and differentiate your products with supercritical CO2.

11/05/2025

This side-by-side comparison highlights how purge vs. no purge conditions affect sterilization. It showcases how process parameters can be optimized to preserve elastomeric material properties.

The NovaGenesis Tech Talk Series connects academic researchers advancing   technology across  ,  , and  . Since 2021, th...
11/04/2025

The NovaGenesis Tech Talk Series connects academic researchers advancing technology across , , and . Since 2021, the series has fostered global collaboration through presentations from leading groups exploring its science and applications.

Explore past topics and speakers:

Explore the NovaGenesis Tech Talk series, hosted by current and prospective NovaGenesis users from leading universities around the world.

Supercritical carbon dioxide is redefining terminal   for   by providing sterility assurance while preserving biochemica...
11/03/2025

Supercritical carbon dioxide is redefining terminal for by providing sterility assurance while preserving biochemical integrity. It operates below physiological temperatures to maintain proteins, growth factors, and structural quality. Explore published clinical outcomes to learn how sterilization is meeting clinician expectations: https://bit.ly/4oNgN8s

  is opening new frontiers for the   industry. At NovaSterilis, we’ve demonstrated its ability to sterilize   and   with...
10/31/2025

is opening new frontiers for the industry.

At NovaSterilis, we’ve demonstrated its ability to sterilize and without compromising biological function. Our work extends into vaccine development and targeted delivery research, pushing the limits of what’s achievable through this sustainable and precise technology. https://bit.ly/3RmkZx8

This video illustrates the depressurization phase of the   sterilization process, capturing the physical dynamics as the...
10/30/2025

This video illustrates the depressurization phase of the sterilization process, capturing the physical dynamics as the system transitions from supercritical to ambient conditions.

Observe the elastic deformation and recovery of the rubber band, and how other polymer materials react differently to the scCO2 process. These visual cues highlight how phase changes of CO2 within the scCO2 process can influence material behavior during .

This video captures the dramatic effects of transitioning out of the supercritical CO₂ state. As the chamber empties, you’ll see:• The rubber band expand and...

Supercritical CO2   offers a technically validated alternative to ethylene oxide with over 500,000 implants already ster...
10/29/2025

Supercritical CO2 offers a technically validated alternative to ethylene oxide with over 500,000 implants already sterilized for human use. Read NovaSterilis CEO Tony Eisenhut’s evaluation on its implementation, scalability, and role in sterilization:

Supercritical CO2 offers a safe, highly effective alternative to EtO sterilization with many applications in the MedTech industry.

Recent studies and global adoption trends show that supercritical CO2   maintains graft strength and biocompatibility wh...
10/28/2025

Recent studies and global adoption trends show that supercritical CO2 maintains graft strength and biocompatibility while achieving sterility assurance levels suitable for clinical use. Explore how this approach is redefining standards: https://bit.ly/4k5NF9B

The   delivers supercritical CO2 performance in a 60 lb., 24”x20”x12” package that is engineered for versatility and pre...
10/27/2025

The delivers supercritical CO2 performance in a 60 lb., 24”x20”x12” package that is engineered for versatility and precision at lab scale to give researchers the control and repeatability they need. Learn more about this system: https://bit.ly/3Ow1SA6

Dive into each stage of the   process, from liquid fill to supercritical transition and return to ambient conditions.  T...
10/24/2025

Dive into each stage of the process, from liquid fill to supercritical transition and return to ambient conditions. This is a look inside the pressure vessel- you can see the supercritical CO2 process—it will get you thinking of the possibilities..

Watch the process in full:

This short timelapse provides a complete perspective of the supercritical CO₂ sterilization process. Watch as the chamber:• Starts clear and empty• Fills wit...

Allograft tendon sterilization SAL6, full cycle 240 minutes.   sterilization is providing clinicians with sterile soft t...
10/23/2025

Allograft tendon sterilization SAL6, full cycle 240 minutes. sterilization is providing clinicians with sterile soft tissue. This study provides process and methods insight with results confirming SAL6 terminal sterility. Med Device and Tissue Banks can draw on this work for their manufacturing process development. Read more: https://bit.ly/3UxVdc3

Balancing sterility assurance with material compatibility is a persistent challenge in   manufacturing. Discover how   s...
10/22/2025

Balancing sterility assurance with material compatibility is a persistent challenge in manufacturing. Discover how sterilization can be an alternative to and traditional terminal methods:

As device complexity increases, supercritical CO₂ is redefining sterilization - going beyond the limits of aseptic manufacturing. Learn more.

Selecting the right   modality can directly influence data integrity and material performance in R&D environments. Learn...
10/21/2025

Selecting the right modality can directly influence data integrity and material performance in R&D environments. Learn how systems enable contamination control for temperature-sensitive materials and complex biomaterials: https://bit.ly/3Bk6t4l

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Lansing, NY
14882

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