10/30/2025
Cavities and gum disease may nearly double stroke risk, new research finds.
A new study published in Neurology Open Access — the official journal of the American Academy of Neurology — found that people with both dental cavities and gum disease had an 86% higher risk of ischemic stroke compared to those with healthy mouths.
Researchers analyzed data from nearly 6,000 adults over two decades, showing that untreated decay and gum inflammation may create a chronic inflammatory burden that damages brain blood vessels and increases stroke risk.
The findings reinforce growing evidence that oral infections can affect the entire body. Bacteria and inflammatory toxins from diseased gums and decayed teeth can enter the bloodstream, triggering vascular inflammation and clot formation.
The study also noted that regular dental check-ups and professional cleanings reduced the likelihood of having both conditions by 81% — proving that maintaining oral health may also protect the brain and heart.
🧾 Journal Reference: Stefanie Wood et al. Combined Influence of Dental Caries and Periodontal Disease on Ischemic Stroke Risk. Neurology Open Access, 2025; 1(4). DOI: 10.1212/WN9.0000000000000036