01/31/2026
Wegovy is now approved in pill form in addition to injections. Woohoo!! This is AWESOME !👏🏼
This may be helpful for those seeking weight loss but worried about the shots 💉
Studies show same efficacy but does show LESS severe GI side effects then injection
4 different doses
Does look cheaper
Compounded not available yet but coming
No word on zepbound pill yet
Here is some education . Let me know if you desire a weight loss consult my local friends! I can likely get you scheduled at the Buford office. ❤️ Just PM me
✅What is Oral Wegovy?
Oral Wegovy (semaglutide) is a once-daily tablet approved by the FDA to help adults lose weight and keep it off. It works by reducing your appetite, helping you feel full longer, and slowing how quickly food leaves your stomach.
Wegovy must be used together with a reduced-calorie diet and increased physical activity.
✅Wegovy is now approved in injection form and pill form.
Doses are below:
Wegovy injection: 0.25mg --> 0.50mg--> 1.0mg--> 1.7mg--> 2.4mg
Wegovy pill 1.25mg--> 4mg--> 9mg--> 25mg
✅Cost if not covered by insurance
Oral Wegovy tablets cost $149-$299 per month depending on dose, compared to $349 per month for injectable Wegovy
✅Weight Loss Results:
In clinical studies, people taking oral Wegovy 25 mg lost an average of 13.7% of their body weight over 64 weeks, compared to 2.3% with diet and exercise alone.
About 70% of people achieved at least 5% weight loss, and nearly one-third lost 20% or more of their body weight.
Approximately 79% of participants taking oral Wegovy achieved ≥5% weight loss, 63% achieved ≥10% weight loss, and 30% achieved ≥20% weight loss—proportions that closely mirror those seen with the injectable formulation.
➡️Important: Wegovy works best when combined with healthy eating and regular physical activity. Weight regain can occur if you stop taking the medication and go bco to old habits a, so this can be a long-term treatment. BUT I do see large percentage of patients who are motivated keep it OFF!!‼️
✅Common Side Effects
Most side effects are gastrointestinal (stomach and digestive) problems that are usually mild to moderate and improve over time:
SEVERE GI side effects appear less with the pill.
For injectable Wegovy 2.4 mg, the most common adverse reactions (≥5% and more frequent than placebo) include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, dyspepsia, dizziness, abdominal distension, eructation, hypoglycemia in patients with type 2 diabetes, flatulence, gastroenteritis, and gastroesophageal reflux disease.
Severe gastrointestinal adverse reactions occurred in 4.1% of injectable Wegovy-treated patients versus 0.9% of placebo-treated patients.
Overall, 6.8% of patients discontinued injectable Wegovy due to adverse reactions, with nausea (1.8%), vomiting (1.2%), and diarrhea (0.7%) being the most common reasons for discontinuation.
For oral Wegovy 25 mg tablets, severe gastrointestinal adverse reactions occurred in 2% of tablet-treated patients versus 0% of placebo-treated patients—notably lower than the 4.1% rate seen with injections.
The gastrointestinal adverse reactions were most frequently reported during dosage escalation for both formulations.
✅Both formulations carry the same warnings for serious adverse reactions, including risk of thyroid C-cell tumors, acute pancreatitis, gallbladder disease, acute kidney injury due to volume depletion from gastrointestinal side effects, and hypersensitivity reactions.
Patients should be monitored for signs of pancreatitis (persistent severe abdominal pain), and renal function should be monitored in those experiencing gastrointestinal reactions that could lead to dehydration.
✅The key practical difference is that oral Wegovy appears to have a lower rate of severe gastrointestinal adverse reactions (2% vs 4.1%), though both formulations have similar overall gastrointestinal tolerability profiles with most reactions being mild to moderate and transient.
Nausea (affects about 47% of people)
Vomiting (affects about 31% of people)
Diarrhea (affects about 30% of people)
Constipation (affects about 24% of people)
Abdominal pain (affects about 20% of people)
Heartburn or acid reflux (affects about 8-18% of people)
These side effects typically occur during the first few weeks and when your dose is increased. They usually last only a few days and resolve without needing to stop the medication.
❌Who Should NOT Take Wegovy❌
Have or have had medullary thyroid cancer
Have a family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Are allergic to semaglutide or any ingredients in Wegovy
Are pregnant or planning to become pregnant (stop Wegovy at least 2 months before trying to conceive)
Have a history of pancreatitis
Remember: Wegovy is a tool to help you lose weight, but it works best when combined with healthy eating and regular physical activity.
🙂❤️
