CHARLES E. HOLMAN FOUNDATION

01/29/2026

Strategies include improved surveillance to track shifting tick ranges, vaccine development to help prevent ill-health, oral prophylactics for high-risk populations, and targeted antibiotics to hit not only the infection but also the resulting inflammatory response.

While significant challenges remain, the increased attention on Lyme disease research hopefully signals a positive and long-overdue step towards improved protection and better outcomes for those affected.

Read more on the emerging research targeting Lyme disease.

https://lymediseaseuk.com/lyme-disease-under-the-microscope/

01/29/2026

People who don't understand Lyme disease might think you are flakey and unreliable. You don't need to explain yourself. Please set healthy boundaries that are right for you, and surround yourself with people who are supporting, understanding, and kind.

01/29/2026

Tick-borne illnesses are evolving, and so is the science behind detecting and managing them. Watch back from our first 2026 webinar to gain timely, practical insights into the latest advances in tick-borne disease research, diagnostics, and clinical approaches—directly from leading experts in the field.

bit.ly/modern2026

01/29/2026

Ever wonder why it’s sometimes difficult to remove a tick?

Ever wondered why it's so hard to pull a tick out? 🕷️ It’s not just biting you—it’s drilling!In this macro 3D animation, we reveal the terrifying biology be...

01/28/2026

A review of the medical literature has found long-term infection in animal models and persistent infection despite antibiotic therapy in humans with

01/28/2026

Our Lyme disease testing and treatment grant applications open on February 16th! 💚 Learn more at https://lymetreatmentfoundation.org/application-information

Lymedisease.org

01/27/2026

Persistent Borrelia Infection in Chronic Lyme Disease: A Review of the Medical Literature

Chronic Lyme disease (CLD) remains a controversial illness. The controversy is based on a profound disagreement over the existence of persistent infection with the Lyme spirochete, Borrelia burgdorferi, and the ability of this persistent infection to cause chronic symptoms in patients who are untrea...

01/27/2026

Congratulations to Raphael Stricker, Melissa Fesler and Lorraine Johnson! What a great way to start out the New Year!

This comprehensive review highlights the evidence in human and animal models for persistent infection as the driver of Chronic Lyme Disease.

Persistent Borrelia Infection in Chronic Lyme Disease: A Review of the Medical Literature

Abstract
Chronic Lyme disease (CLD) remains a controversial illness. The controversy is based on a profound disagreement over the existence of persistent infection with the Lyme spirochete, Borrelia burgdorferi, and the ability of this persistent infection to cause chronic symptoms in patients who are untreated or undertreated for the spirochetal disease. Based on a review of the medical literature, we identified 56 studies confirming B. burgdorferi persistence. In this article, we summarize evidence from animal models and human studies that support persistent spirochetal infection as the cause of CLD. Specifically, direct and functional testing using culture, histology and xenodiagnosis has shown viable organisms following antibiotic therapy, and the potential role of cysts (L-forms) and biofilms in this process is examined. Future studies are required to investigate the mechanism of persistent infection in CLD.

Persistent Borrelia Infection in Chronic Lyme Disease: A Review of the Medical Literature

Chronic Lyme disease (CLD) remains a controversial illness. The controversy is based on a profound disagreement over the existence of persistent infection with the Lyme spirochete, Borrelia burgdorferi, and the ability of this persistent infection to cause chronic symptoms in patients who are untrea...

01/27/2026

Deadline Jan. 30th: Register Today for the 2026 Virtual Advocacy Day!
Please join us for the Center for Lyme Action 2026 Virtual Advocacy Day on Feb. 18, 2026! Thank you to all advocates for your efforts to grow federal funding for Lyme, Alpha-gal and tickborne diseases! Our collective efforts have grown federal funding by more than $500 million since we started. Register today and together we will work on FY27 appropriations.

This event is for US citizens only. All training sessions and meetings will be held via Zoom. Please see the overview of the new event and training schedule below. Full details of training and event schedule available.

Register for the Center for Lyme Action 2026 Virtual Advocacy Day!

Join us to advocate for Lyme, Alpha-gal & tick-borne disease federal funding!

Calling all advocates passionate about Lyme and tick-borne diseases! invites you to be part of our Virtual Advocacy Day aimed at growing FY27 federal funding for Lyme and tick-borne disease research, prevention, and response.

✨ Our combined efforts have grown federal funding by half a billion dollars, and now, we aim to continue this positive trajectory.

📅 Mark your calendars:

Event Schedule:

Welcome Session: Recorded for you to watch at your convenience in the days leading up to the event.

Meetings with Congress: Wednesday, February 18, 2026 (full day)

Trainings: Learn about the new and improved training schedule on our website centerforlymeaction.org/events

🤝 Your advocacy matters! Let’s ensure our voices are heard and secure vital resources for Lyme and tick-borne disease initiatives.

Visit the link in bio to register! Your commitment is invaluable in shaping the future of Lyme and tick-borne disease funding.

For more information, email info@centerforlymeaction.org or visit the website. Together, let’s make an impact!

01/27/2026

Support for UK patients

💚 Every day, people share their experiences - struggles, triumphs, questions - and our community responds with understanding, advice, and encouragement.

If you or someone you know is navigating a Lyme disease diagnosis, feeling unsure about symptoms, or looking for guidance on treatment and daily life, you are not alone.

🤗 Join our network, connect with others who truly understand, and access the trusted information and support that can make a real difference.

https://www.facebook.com/groups/LymeDiseaseUK