02/19/2026
📴 Can we flip the switch on nutrients? Let’s talk about when “essential” isn’t always safe.
As nutrition professionals, we’re trained to focus on meeting requirements; balancing macro- and micronutrients to support health. But what’s often overlooked is this critical nuance:
👉 The same nutrients that sustain life in a healthy dog can become harmful in certain disease states.
Let’s spill the beans.
🔬 Copper
Vital for hematopoiesis, connective tissue integrity, and antioxidant enzymes in healthy dogs.
But in cancer, copper plays a role in angiogenesis and tumor stabilization, potentially supporting tumor growth when dysregulated or excessive.
🩺 Phosphorus
Essential for ATP production, skeletal health, and cellular signaling.
In renal disease, impaired excretion leads to phosphorus accumulation, driving secondary hyperparathyroidism, vascular mineralization, and faster disease progression.
🦴 Calcium
Crucial for neuromuscular function and bone metabolism.
Yet in conditions like calcinosis cutis, calcium deposition in soft tissues becomes part of the pathology—not a benefit.
🧬 Carbohydrates & glutamine
Perfectly appropriate energy substrates in health.
But in many cancers, these nutrients can be preferentially utilized by malignant cells to support rapid proliferation and metabolic reprogramming.
🧪 Urolithiasis (bladder stones)
Minerals such as calcium, phosphorus, magnesium, and purines are all essential.
Yet depending on stone type (ex., calcium oxalate, struvite, urate), these nutrients may need restriction, redistribution, or urinary manipulation.
⚠️ The takeaway:
Nutrition does not exist in a vacuum. Requirements are not universal. Disease changes metabolism, utilization, tolerance, and risk.
This is why “balanced” is not synonymous with “appropriate,” and why therapeutic nutrition must always be context-specific, pathophysiology-driven, and individualized.
If you’ve ever been told “it’s a required nutrient, so it must be safe”—this is your reminder that biology is far more complex than a spreadsheet.
Let’s keep having the conversations that matter. 🧠💚
— The Holistic Canine 🐾 theholisticcanine.us
The Holistic Canine provides advanced clinical nutrition services for dogs with diagnosed medical conditions, complex health histories, and medically sensitive nutritional needs 👇
https://theholisticcanine.us/services/clinical-canine-nutrition/