04/27/2026
What's the difference between over-the-counter vs. professional/medical-grade skincare?
Over-the-counter skincare can be wonderful for basic cleansing, hydration, and maintenance — but many formulas are designed for the masses, with lower concentrations of active ingredients.
Professional lines like iS Clinical and SkinMedica are designed differently:
✔ Higher concentrations of proven actives
✔ Advanced delivery systems to help ingredients pe*****te more effectively
✔ Clinically researched formulas
✔ Targeted correction for pigmentation, aging, acne, texture and collagen support (
And that’s where the results can be dramatically different.
Think of it this way…
Over-the-counter often maintains. Medical-grade will correct.
Yes, the investment can be higher — but when you’re using products that actually perform, you save money by no longer buying “hope this works” products.
In this case, you really do get what you pay for. ✨