Nikon Microscope Solutions

Nikon Microscope Solutions Nikon has over 100 years of optical experience and remains the only microscope company to manufacture its own glass.

The official account for the Life Science Solutions division of the Nikon Healthcare Business, with a focus on biological microscopy products and services for the life science, biotech/pharma, and clinical laboratory markets. We are here to be your trusted partner in imaging – from basic microscopes to the latest high-end scientific imaging technologies, including advanced confocal and super-resolution options. Our global corporate mission statement centers on promoting trustworthiness and creativity. We are focused on shedding new light on healthcare by accelerating imaging innovation in key fields such as regenerative medicine and drug discovery, as well as life science research more broadly. Ultimately, our goal is to help people around the world realize a better quality of life. We also run Nikon’s annual Small World competitions – globally recognized for over 50 years as the leading forum for showcasing the beauty and complexity of life as seen through the light microscope. To find contact information for your world area, please visit our website here: https://www.microscope.healthcare.nikon.com/contact

🌸Spring Cleaning Series - How to clean oil immersion objectives✨Today, we’re focusing on cleaning your oil or silicone o...
03/25/2026

🌸Spring Cleaning Series - How to clean oil immersion objectives

✨Today, we’re focusing on cleaning your oil or silicone oil immersion objectives. Clear data starts with a clean lens, but high-NA objectives are as delicate as they are expensive.

🔗 Download full instruction here: https://bit.ly/4sOfjgF

03/24/2026

🧠Our brains are wired through intricate networks of neurons that must connect in just the right way to work properly. During development, each neuron extends branching dendrites (delicate “wires” seeking connections) while also making sure not to overlap its own branches. This process, called dendritic self‑avoidance, helps keep communication lines clear so the brain’s circuitry can form efficiently.

🔬Researchers from the University of Osaka have uncovered that a molecule called Protocadherin γC4 (Pcdh‑γC4) plays a crucial role in helping neurons survive and organize their dendrites. The team found that neurons lacking this protein were more likely to die and showed tangled dendritic patterns instead of the orderly spacing seen in healthy cells. In essence, γC4 acts like a “guidance and safety” signal for developing neurons.

💡These findings shed light on how fine‑tuned molecular systems safeguard brain wiring from early development onward. Understanding how proteins like Protocadherin γC4 work could provide clues to neurodevelopmental or degenerative disorders and inspire new strategies to support neuronal health and repair in the future.

🔗 Read the paper: https://www.nature.com/articles/s42003-026-09778-6

03/23/2026

🧐Need a reliable objective for extended live cell imaging?

✅Our Lambda S silicone objectives are specially designed for observing live samples over long periods of time. Perfect for time-lapse imaging, these objectives use silicone oil with low volatility, even at 37°C, ensuring that your immersion medium remains stable without evaporation.

🔗Learn more about the CFI Plan Apochromat/Apochromat Lambda S Series here: https://bit.ly/4bBJnVe

Images: Neutrophil flowing in blood vessel (time-lapse) Images courtesy of: Professor Masaru Ishii, Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University

👀 Struggling with complex setups or compromised image quality? This configuration might just be it for you - Nikon’s sma...
03/20/2026

👀 Struggling with complex setups or compromised image quality? This configuration might just be it for you - Nikon’s smart imaging platform ECLIPSE Ji with the AX confocal system provides a simple yet powerful imaging solution for your daily routine experiments.

Curious to learn your cost-effective configuration options? Contact your local Nikon representative today 👉 https://bit.ly/4uGNuYQ

03/19/2026

🌟This demonstrates how the NSPARC excels not only in the visible spectrum but also in the near-infrared range, opening possibilities for your research! The high sensitivity and resolution make it an indispensable tool for cutting-edge applications.

📩Curious about how these improvements can benefit your work? Reach out to us for more details! 👉 https://bit.ly/4rETGO8

🔬Sample: Cell 4C NIR from Gattaquant - DAPI (light blue), TOMM20 AF488 (yellow), Actin AF647 (indigo), Tubulin AF750 (magenta)

03/18/2026

🌷Spring Cleaning: Maintain your microscope camera for image quality and data integrity.

🤝Our Digital Sight 10 maintenance guide covers routine care, cleaning the camera body and mount interior, and safe sensor‑cleaning procedures so you can maintain precision imaging. Watch this short guide to help you navigate how to clean its sensor.

🔗Check out the full guide here: https://bit.ly/4buQv5z

03/17/2026

🍽️ Metabolic dysfunction-associated steatotic liver disease (MASLD) is now one of the fastest‑rising causes of liver cancer.

Ghiles Imerzoukene and colleagues, in collaboration with the Nikon Center of Excellence at APEX PAnTher INRAE Oniris Nantes, uncovers a key driver of this progression: the necroptosis protein MLKL.

Using mouse models, the team shows that MLKL in liver parenchymal cells promotes inflammation, fibrosis (assessed using the collagen SHG signal acquired with the A1R MP multiphoton microscope), and ultimately hepatocellular carcinoma development under metabolic stress. When MLKL is deleted specifically in these cells, disease progression and tumor formation are significantly reduced.

🧩 These findings reveal a direct link between MLKL and cancer initiation in fatty liver, pointing to MLKL as a promising therapeutic target in MASLD‑associated liver cancer.

Read the paper👉 https://www.nature.com/articles/s41419-026-08458-x

03/16/2026

🎥 Our latest webinar archive, Spatial Transcriptomics in 3D: Automated MERFISH on a Nikon Platform, presented by Professor Jonathan Brewer, is now live.

👀 Missed the live session? You can now access the complete recording to explore the highlights and technical insights at your own pace.

👉Check out now: https://bit.ly/3P2V67L

🌸 Our Spring Cleaning Series continues with a focus on the proper handling and disinfecting procedures for your Nikon Mi...
03/11/2026

🌸 Our Spring Cleaning Series continues with a focus on the proper handling and disinfecting procedures for your Nikon Microscope equipment.

🔬 In a shared lab environment, maintaining high standards of cleanliness is vital for both hygiene and optical performance.

🎥 Looking for more? Visit our YouTube channel to see our complete collection of microscope maintenance tutorials: https://bit.ly/40TM7Z1

03/10/2026

Every cell in our body constantly senses and reacts to physical forces, from the stretch of muscle fibers to the gentle touch on our skin 🤲. Understanding how cells convert these mechanical cues into biological signals, a process called mechanotransduction, helps scientists uncover how tissues grow, heal, and sometimes malfunction.

🤖 In a new Nature Communications study, researchers from Harbin Institute of Technology designed gear‑shaped microrobots built from metal–organic frameworks (MOFs), materials known for their precise, customizable structure. These micro‑gears can gently interact with a cell’s microvilli, delivering controlled pushes and twists while tracking how the cell responds in real time. This gives scientists a window into the mechanics of life at the single‑cell level.

🩺 Such technology could one day help unlock how physical forces influence processes like immune responses, cancer progression, and tissue regeneration. By bridging micro‑robotics and cell biology, we’re learning not just how cells move, but how they feel and react to the world around them.

Read the full paper: https://bit.ly/4rSCm9g

👀In the world of fluorescence imaging, "good enough" is the enemy of "groundbreaking."✨To help you move from troubleshoo...
03/09/2026

👀In the world of fluorescence imaging, "good enough" is the enemy of "groundbreaking."

✨To help you move from troubleshooting to discovery, we’ve released our latest visual guide: Illuminating Biology in Colour. A useful reference for anyone looking to refine their fluorescence imaging workflow.

📥 Download the high-res poster here: https://bit.ly/4basvEG

💜 Happy International Women’s Day! 💡Seeing a clearer future, powered by women.🔬We are honored to support the visionary w...
03/08/2026

💜 Happy International Women’s Day!

💡Seeing a clearer future, powered by women.

🔬We are honored to support the visionary women dedicating their careers to advancing human health and deepening our understanding of the world through science.

Address

1300 Walt Whitman Road
Melville, NY
11747

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

Telephone

(800) 526-4566

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https://www.nikonsmallworld.com/

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