McGuffee's Drug Store

McGuffee's Drug Store McGuffee Drugs is a family drugstore located in Mendenhall, Mississippi.

We are an independently owned and family operated pharmacy that’s been filling prescriptions for 51 years now.We’re your one stop for prescriptions, healthcare advice, gifts, and electronics!

01/30/2026

Feeling like stress is standing between you and your health goals? Don’t worry—you’re not alone! Here are a few simple ways to lower stress levels and get back on track toward your wellness journey.

We are honored to have been nominated Simpson County’s Best Pharmacy!! We are thankful for all of your support every day...
01/30/2026

We are honored to have been nominated Simpson County’s Best Pharmacy!! We are thankful for all of your support every day! 💊💉

King Cakes are here!! LIKE AND SHARE TO WIN A LARGE!! Flavors: Blueberry Cream Cheese Strawberry Cream Cheese Cream Chee...
01/29/2026

King Cakes are here!!
LIKE AND SHARE TO WIN A LARGE!!

Flavors:
Blueberry Cream Cheese
Strawberry Cream Cheese
Cream Cheese
Pecan Praline
Strawberry Bavarian Cream ✨NEW✨
Bavarian Cream

As we welcome the new year, creating a steady routine can be one of the kindest things you do for your mind. Predictabil...
01/23/2026

As we welcome the new year, creating a steady routine can be one of the kindest things you do for your mind. Predictability helps reduce stress and makes everyday tasks feel more manageable. Whether it’s organizing your meds or setting small daily goals, little steps go a long way. We’re always here to support your wellness journey, one day at a time. Click on the link below for more information on how a set routine can do wonders for your mental health!

https://mcpress.mayoclinic.org/mental-health/the-mental-health-benefits-of-routine/

💜💚Come grab a king cake or two on this rainy day! We have plenty at the moment, but they will go out the door fast!💚💜
01/22/2026

💜💚Come grab a king cake or two on this rainy day! We have plenty at the moment, but they will go out the door fast!💚💜

Make a resolution that sticks: switch to a pharmacy that knows your name! 💊 Transfer your prescriptions today and enjoy ...
01/21/2026

Make a resolution that sticks: switch to a pharmacy that knows your name! 💊 Transfer your prescriptions today and enjoy personal, neighborhood care all year long.

🪩SALE ITEMS🪩 Be sure and check out all the goodies that we have marked down! These will go out the door fast, so don’t ...
01/21/2026

🪩SALE ITEMS🪩

Be sure and check out all the goodies that we have marked down! These will go out the door fast, so don’t miss out!

01/20/2026

King Cake Giveaway Winner!!!

💚💜💛This weeks give away!!! LIKE AND SHARE! Drawing is at 5:30 TONIGHT!!!
01/20/2026

💚💜💛This weeks give away!!! LIKE AND SHARE! Drawing is at 5:30 TONIGHT!!!

01/19/2026

If you're thinking about quitting smoking this year, you should know that the positive effects begin immediately after your last cigarette. Learn more about the health benefits you can expect within your first month of quitting.

01/19/2026

KING CAKES WILL BE IN TOMORROW AFTERNOON!!!

3 chocolate Bavarian cream size medium on sale today!!

The new year is the perfect time to prioritize your health, both mental and physical. Did you know psychological stress ...
01/16/2026

The new year is the perfect time to prioritize your health, both mental and physical. Did you know psychological stress can increase your risk of heart disease by 40%-60%? Start 2026 with self-care, stress management, and a commitment to wellness. Your heart will thank you!

Address

102 N Main Street
Mendenhall, MS
39114

Opening Hours

Monday 8am - 6:30pm
Tuesday 8am - 6:30pm
Wednesday 8am - 6pm
Thursday 8am - 6:30pm
Friday 8am - 6:30pm
Saturday 8am - 5pm

Telephone

+16018472511

Website

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