02/15/2026
🌸 Perimenopause & Depression — It’s Hormonal, Not Random
During the menopause transition, women face a 2–5× higher risk of depression, even with no prior history.
Why? It’s not just “low hormones” — it’s hormone instability.
Fluctuations in estrogen and progesterone directly impact serotonin, GABA, and stress regulation in the brain.
📊 Evidence:
A 2018 JAMA Psychiatry trial found women on transdermal estradiol + micronized progesterone were ~50% less likely to develop depressive symptoms vs placebo.
💡 Takeaway:
Mood changes in perimenopause are biological, common, and treatable.
You’re not broken — your hormones are shifting, and support is available.
📍 Treasure Valley Pain & Hormones
2102 W Everest Ln, Suite 100
Meridian, Idaho
📞 Call or text 208-505-4744
👉 Click the link in our bio for appointment requests.
**INSURANCE ACCEPTED
✨ In-person and telehealth appointments available for Idaho patients.