10/27/2025
There is a current lawsuit against Pfizer regarding the association between Depo-Provera and meningiomas...brought by 10,000 women who took Depo-Provera and were later diagnosed with a meningioma. Pfizer was upfront about warnings in other countries as far back as 2015, but not in the U.S.
The association has been seen with injectable Medroxyacetone acetate (MPA) which is a progestin (synthetic progesterone) - ie: Depo-Provera.
There is not a lot of awareness, and if you have taken Depo-Provera and have symptoms of meningioma (headaches, dizziness, vision changes, seizures, etc), please insist on an MRI. Insurance is covering them for this.
Progestins (all forms) are known to be inflammatory to women, and have many potential side effects.
Progesterone (the bioidentical form) is an anti-inflammatory for women, and has a lot of benefits.
Please do not confuse the two, even when articles/studies refer to progestins as "progesterone."
Medroxyprogesterone acetate is a synthetic progesterone commonly used as a contraceptive in the United States, used by up to 25% of women aged 18–49 who have had in*******se. Progesterone is reported to be associated with the increased growth of ...