Matilde Hague fighting Pancreaticobiliary cancer

08/15/2025

Today is August 14th. Went into MD Anderson this morning to have blood tests done and then met with the clinical trials team. Thank God my white blood cells and platelets were in normal ranges. Will check again in one week. Looks like I should be on schedule to get another treatment on August 28th.

08/09/2025

Sorry for not updating earlier. I was previously on a trial treatment of chemotherapy and a targeted therapy drug. It was working but it made me very sick to the point that my body could not handle. I was taken off all treatments for 5 weeks. I was switched over to the MD Anderson clinical center for targeted therapy. I had my first trial therapy on July 17th. It was a 17 hour process. It made me very weak and tires for 4 days. The next week I got admitted into the MD Anderson hospital for 5 days because my white blood cells and platelets were dangerously low. Lots of injections into the stomach to stimulate the bone marrow to produce white blood cells. Also had lots of platelet transfusion. On the second day I got hit with excruciating pain in back, chest and abdomen. Took 6 1/2 hours of heavy pain meds to knock me out. The next morning it was gone. They took x rays and an extensive MRI. They did not find any abnormalities besides my existing cancer. I was released in the 5th day so I could try to rest up. Three days later they checked the blood levels and thank God it was continuing to improve. Three days later (Aug 7th) they ran blood work and then met with the doctors and we decided to proceed with the second treatment. The scientist came up with a lower dosage that they hope will still be effective and not put me in the hospital again. This Sunday I have blood work and they will give me an injection to stimulate the growth of white blood cells. Then they will check the blood levels again Thursday. This will be the day to find out how bad the levels have dropped. These trials are very tough. Every few days they are running tests to make sure I am alright. I will get this treatment every three weeks. On August 27th they will do a ct scan to get an update. They will run a ct scan every 6 weeks. I am having to stay close to the MD Anderson hospital in Houston until 4 days after the 4th treatment. Just the expenses to stay here for 10 weeks are astronomical, not even to mention that insurance jo longer helps much due to the fact that it is atrial treatment. So any financial support would be greatly appreciated. Not going to be able to continue this without financial help. As always I place my fate in God’s hands. Thank you and God bless everyone.

https://gofund.me/e6eb81ca

05/09/2025

Update
Met with MD Anderson on 5/625 No new tumors or growth. Some tumors have decreased. So it is still controlled. Took her off the chemo infusions and will continue taking the experimental drug. The two treatments combined made her very sick. Has to go back on blood thinners. Small clot by her port. Lymph node in Trachea area has increased in size so they will continue to monitor. Next appointment they will consider a localized treatment to kill off more tumors. Surgery is still not an option.
Keep the prayers coming

03/30/2025

Please share with your contacts. She has gone thru all FDA approved treatments and now they are trying combinations of treatments. Insurance is no longer any help.

Hi, my name is Matilde Hague. On 9/19/23. I was diagnosed with Pa… Matilde Hague needs your support for Matilde continues fighting for her life against cancer

03/30/2025

https://gofund.me/21b6fcbc

Hi, my name is Matilde Hague. On 9/19/23. I was diagnosed with Pa… Matilde Hague needs your support for Matilde continues fighting for her life against cancer

03/30/2025

Sorry for not posting an update, but this double treatment has been very hard. I went back to MD Anderson the first week of March. Lots of blood work, meting with targeted therapy trial doctor, ct scan, meeting withe my main oncologist and a liver biopsy. A week before I went to Houston I had to stop the trial meds because the side effects were so bad, they were afraid that I would end up in the hospital. Oncologist was very happy with the ct scan reports and blood work. He said that the cancer is controlled and may have reduced some in size. He wants me to continue both treatments but they have backed off the dosage so I wont have such bad side effects. So far I have been able to handle both of them. I need to return to MD Anderson the first week in May and see if it is still controlled. I recently got a call from the trials team saying that the test that was done on part of the tissue from the liver biopsy came back that I am qualified for a new clinical trial treatment. If and when I will start this will be up to my main oncologist. No reason to do it now since the current treatments are working. If I have to do the clinical trials I will have to be in Houston for 10 weeks and every thee weeks after that. A total treatment time of nine months. Of course insurance will not help since it is a trial. Insurance wont even cover the pills that I am taking because they do not have FDA approval for my type of cancer. So if anyone can help out with donations it would be greatly appreciated. Keep the prayers coming.

https://gofund.me/21b6fcbc

01/11/2025

It’s January 11, 2025. I am still fighting and beating all the odds. On December 30, 2024 I started a different type of chemotherapy. One of drugs us given by IV and the other is given over 46 hours by a pump connected to my port. This treatment is every two weeks. I have it again on January 13th. On January 8th I started taking a trial targeted therapy drug. I will continue with both treatments as long as the side effects are tolerable. On January 16th, I have a video conference call with the MD Anderson clinical trials team to discuss other available options. I get scans on March 3rd to see if the cancer has stabilized. Meanwhile I keep fighting and leave my fate in God’s hands.

12/20/2024

Ok i will try to summarize the six hours at md anderson yesterday. Very frustrating time with clinical trials team and sometime conflicting information until the clinical doctor talked me. He said he sent some trial options to my md anderson oncologist and that it would be up to the oncologist on how he wants to proceed. I met with the oncologist and he said he did not like the options that the clinical doctor suggested. He said maybe later but now. He said that I will start a different type of chemotherapy that has been approved. It will be once every two weeks and will be done in Midland. Return to MD Anderson in two months for scans and evaluate if the dosage needs to be modified. He is giving me a dosage that should not give much side effects. Meanwhile he asked the trial team to perform pre screening of a new targeted drug. They have to analyze tissue to look for a specific tumor marker. Also he has started the process to get approval for a pill that is approved for lung cancer but not my type. He thinks it will work. It takes time to get the permissions required so he has started the process so it will be available if needed in the future. Basically he is preparing to have the next treatment ready for when the chemo no longer works. I will be back home Saturday afternoon.

12/11/2024

December 19th have to be back at MD Anderson. Bloodwork, meetings with clinical trials team and the oncologist. They are going to determine if I qualify for Phase 1 clinical trials. If I get qualified, will have to spend a lot of time in Houston.

11/29/2024

It’s November 29.2024
Spoke with doctor this Wednesday afternoon. He is surprised that I am feeling so good. Some of the smaller tumors have grown a small amount. They also discovered 5 more tumors in my liver. I need to continue the medicine for now. They are trying to get approval for a different targeted therapy. They are arranging for meetings with the clinical trial department. I have to be back to speak with doctor and clinical trial team in three weeks. He wants to get something different started ASAP so it does not grow much. He is still hopeful that they can control it but it was very disappointing news.