University of Minnesota MSTP (MD/PhD)

03/02/2026

Check out the first author paper by John Lozada in Cancer Immunology Research titled "Integrated single-cell profiling reveals dichotomous NK cell populations associated with immunosuppression in solid tumors".

Natural killer (NK) cells represent key effectors of antitumor immunity, yet emerging evidence highlights populations with distinct roles in cancer. Despite such expanded diversity within the NK cell repertoire, we lack an understanding of how this heterogeneity impacts immune responses and downstre...

02/02/2026

Check out the first author paper by José Valentín López in Clinical Cancer Research titled "Evolution of AR and non-AR alterations in circulating tumor DNA of metastatic prostate cancer patients treated in the phase 3 Alliance A031201 trial".

AR alterations in ctDNA accumulate at progression in mCRPC patients treated with ARPIs, especially in those with initially durable responses. These findings support the use of liquid biopsy to serially track resistance mechanisms and inform precision therapy in advanced prostate cancer.

01/29/2026

🎉 Congratulations to Drs. Rothlin and Masopust! 🎉 We’re proud to celebrate their recognition by the American Association of Immunologists.

🏆 Carla V. Rothlin, PhD — AAI Lancefield Mid-Career Achievement Award
🔗 https://bit.ly/464gkaQ

🏆 David Masopust, PhD — AAI Meritorious Career Award
🔗 https://bit.ly/4a2oL7I

01/26/2026

Check out the first author paper by Saurin Kantesaria in Magnetic Resonance Medicine titled "Designing B1-selective pulses by frequency modulating in a second rotating frame".

By implementing frequency modulation in a second rotating frame, B1-selective excitation and inversion are feasible, even when B0 and B1 are nonuniform.

01/05/2026

Check out the co-author paper by Jacob Noeker in Nature Neuroscience titled "Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus".

The endocannabinoid (eCB) system is involved in many processes in brain function. eCBs depress synaptic transmission by directly activating presynaptic CB1 receptors (CB1Rs), and they indirectly potentiate adjacent synapses by activating astrocytic CB1Rs. In contrast to other neurotransmitter system...

12/22/2025

Check out the first author paper by Andrea Maxwell in Scientific Reports titled " JAACAP Open titled "Using explainable machine learning to elucidate social and neurobehavioral risk factors linked to nonmedicinal opioid use in young adults."

Using explainable machine learning to elucidate social and neurobehavioral risk factors linked to nonmedicinal opioid use in young adults

12/17/2025

12/15/2025

Check out the co-first author paper by Andrea Maxwell in JAACAP Open titled "Environmental, health, and psychological factors predict alcohol sipping in childhood: a machine learning analysis of the ABCD study".

We worked to ensure s*x and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. We worked to ensure se...

11/25/2025

2025 ABRCMS is in the books! We are delighted to be able to support this important conference. And congratulations to pre-MSTP students Jeriel and Carlie on their awards!

11/21/2025

Excited to be at ABRCMS 2025. Stop by Booth 721 to learn about MD/PhD, PhD, and pre-MSTP and other summer research programs.

11/20/2025

Give to the Max Day has arrived! Please consider making an investment in the next generation of physician scientists. Your gift will go twice as far thanks to a generous match. Thank you!

Crowdfunding for University of Minnesota causes

11/20/2025

Give to the Max Day is underway! Please join our other generous donors in supporting our MSTP and the training of the next generation of physician scientists. Thank you!

Crowdfunding for University of Minnesota causes