Vast Therapeutics

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Vast Therapeutics

Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from Vast Therapeutics, Pharmaceutical Company, 615 Davis Drive, Morrisville, NC.

01/02/2026

As we close out 2025, we’re humbled and grateful for what this year has brought and what lies ahead. At Vast Therapeutics, our mission has always been clear: to develop breakthrough therapies that help people with chronic lung disease breathe better and live more fully.

This year brought meaningful milestones toward that mission:
-We completed a key milestone in our Phase 1 clinical program for our lead candidate ALX1, advancing it safely and thoughtfully through important early testing.

-We were awarded significant NIH funding to support our work against rare and challenging lung infections, a vital step forward in our science and hope for patients.

-Our team secured orphan and qualified infectious disease designations, reflecting the potential impact our therapies could have for people with rare respiratory diseases.

None of this would be possible without the support of our community: patients, partners, researchers, and believers in better respiratory health.
Thank you for your trust, encouragement, and shared commitment to innovation that matters.
Here’s to moving closer to transformative medicines in 2026 and beyond together.
💙 With gratitude,
Team Vast Therapeutics

12/09/2025

Bronchiectasis is permanent and progressive, making patients at risk for rare lung infections. Learn about John Torrence's journey with NTM pulmonary disease on the latest episode of Rare and Real on our YouTube channel here: https://youtu.be/ys4kuqrSefE?si=Wi0TAYWlWfXAIc-l

12/05/2025

John Torrence didn't plan to have to live his life every day with Bronchiectasis, but on his 50th birthday, everything changed. Listen to his story on our latest episode of Rare and Real on our YouTube channel here: https://youtu.be/ys4kuqrSefE?si=5qIQsqYW12_SduZc

11/28/2025

Wishing you a happy Thanksgiving holiday from all of us at Vast Therapeutics.

11/27/2025

Having spent years feeling neglected by the pharmaceutical industry, John Torrence is now hopeful about Vast's efforts to develop a non-toxic option for patients with NTM and bronchiectasis.

Watch the full interview on our latest episode of Rare and Real on our YouTube channel here: https://youtu.be/ys4kuqrSefE?si=0rKNlFBr1x9KXNKK

11/19/2025

We’ve successfully completed the Single Ascending Dose (SAD) portion of our Phase 1 study for our lead candidate, ALX1, an inhaled, nebulized pro-drug designed to deliver nitric oxide directly to the lungs. At all four dose levels in healthy adults, ALX1 was well tolerated with no serious adverse events.

This milestone paves the way for our next steps: the Multiple Ascending Dose (MAD) portion is already underway, and we’re aiming to initiate our Phase 2 study in patients during H1 2026.

We’re incredibly proud of the team, our participants, and our mission: to transform treatment for chronic lung diseases like bronchiectasis, cystic fibrosis, and beyond.

Read the full release here: https://www.vasttherapeutics.com/vast-therapeutics-completes-first-milestone-in-phase-1-clinical-program/

09/23/2025

Non-tuberculous mycobacteria (NTM) are naturally occurring bacteria found in soil and water. For many, they pose little risk, but for those living with chronic lung diseases, NTM can cause serious and persistent infections that impact quality of life.

09/19/2025

Ella Belasa has been battling Pseudomonas her entire life. We believe it's going to take multiple therapies and great scientific strides to win the battle for those living with rare lung disease. Watch the interview here: https://youtu.be/pGX1krKTnqM?si=7qAnHi3DJT6erPSB

09/17/2025

Vast Therapeutics has been awarded a second $2 million grant to accelerate our efforts in combating rare respiratory diseases.

This funding supports the development of groundbreaking therapies designed to bring hope to patients and families affected by these challenging conditions.

We’re grateful for the recognition and support of our work, and excited to continue advancing the science of respiratory health.

Read the full press release here: https://www.vasttherapeutics.com/vast-awarded-another-2-million-grant-to-combat-rare-respiratory-disease/

09/11/2025

Pseudomonas is one of the leading causes of serious issues for those living with chronic lung disease. Watch the full interview with Ella Belasa and how she perseveres despite the difficulties that Cystic Fibrosis presents. https://youtu.be/pGX1krKTnqM?si=7qAnHi3DJT6erPSB

08/01/2025

We're thrilled to report that not long after our interview with Amber Harris on our Rare and Real series, she received her new lungs!

She went in for the transplant surgery less than a week after our conversation, and she is recovering very well, surrounded by her amazing support system of friends and family.
Please join us in wishing Amber continued recovery and lifelong health and happiness!

07/17/2025

Imagine struggling to breathe for decades, with no name for what you’re living through. That was the reality for Amber Harris, who lived 44 years before finally being diagnosed with Primary Ciliary Dyskinesia (PCD).

PCD is a rare, often misunderstood lung condition that can go undiagnosed for years, sometimes decades, leaving patients vulnerable to chronic infections and lung damage.

This story isn’t just personal, it’s a wake-up call for awareness, research and innovation.

At Vast Therapeutics, we’re developing solutions that go beyond managing symptoms. We’re committed to targeting the root causes of lung infections, including Pseudomonas aeruginosa, which disproportionately affects those with PCD, cystic fibrosis, and other rare lung conditions.

Address

615 Davis Drive
Morrisville, NC
27560

Website

http://www.vasttherapeutics.com/

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