03/26/2025
Here is a brief article on depression. It may help you understand this mental illness in more depth.
What is Major Depression?
First, let me tell you what it is not! It is not temporary or intermittent moments of sadness, having a bad day or “feeling down or having the blues occasionally.” It can be a disabling and serious mental illness for which various treatments and medication are available. Major depression, also known as Major Depressive Disorder (MDD), is a serious mental health condition that affects millions of people worldwide. It is characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities that were once enjoyable.
What are the symptoms?
The symptoms of major depression can vary from person to person but generally include:
• Persistent sad, anxious, or "empty" mood. Feelings of hopelessness or pessimism
• Loss of interest or pleasure in hobbies and activities. Irritability
• Feelings of guilt, worthlessness, or helplessness Decreased energy or fatigue
• Difficulty concentrating, remembering, or making decisions Insomnia or oversleeping
• Thoughts of death or su***de, or su***de attempts. Appetite or weight changes
What causes Major Depression?
The exact cause of major depression is not known, but it is believed to be a combination of genetic, biological, environmental, and psychological factors. Some common risk factors include:
• Family history of depression Major life changes, trauma, or stress
• Certain physical illnesses and medications Substance abuse.
Treatment
Major depression is treatable, and many people find relief through a combination of therapies. Common treatments include:
• Psychotherapy: Also known as talk therapy, it involves working with a mental health professional to address the emotional and psychological aspects of depression.
• Medication: Antidepressants can help to balance chemicals in the brain that affect mood and emotions.
• Lifestyle Changes: Regular exercise, a healthy diet, and adequate sleep can improve symptoms.
• Support Groups: Connecting with others who are experiencing similar challenges can provide comfort and understanding.
• Other methods of treatment include: ECT (Electric Convulsive Therapy, TMS (Transcranial Magnetic Stimulation), VNS (Vagal Nerve Stimulation), Ketamine or Esketamine (Spravato). To name a few.
Conclusion
Major depression is a serious but treatable condition. Early intervention can lead to better outcomes and improve the quality of life for those affected. In your work here at Packard and personal lives, I hope this brief information on depression will help you relate more deeply to those who struggle with this illness. We need to let go of shame and stigma regarding mental health and seek help when necessary and develop a deeper sense of empathy for those who suffer from this illness.
If you would like to learn more, information is available online from The Mayo Clinic, The Cleveland Clinic and other sources.
Michael T. Gadson, MD
Medical Director
Packard Mental Health Center
