04/15/2026
News from our collaborators!
Check out this news from Accelerated Cure Project for MS:
How do MS symptoms evolve across the lifespan?
As individuals with multiple sclerosis age, immune function changes (immunosenescence), and normal aging processes can influence mobility, cognition, and other neurological functions. These shifts raise important questions about how MS-related symptoms behave over time.
While longitudinal disability measures such as DSS/EDSS provide insight into overall progression, less is known about the trajectory of individual symptoms and whether stabilization or decline occurs at specific life stages. This uncertainty also intersects with complex clinical decisions, including long-term disease-modifying therapy considerations in older populations.
Clarifying age-related symptom trajectories could improve prognostic counseling, support individualized care planning, and inform evidence-based treatment decisions in later life.
This question was prioritized by Accelerated Cure Project’s iConquerMS community through the PRADA project, where people with MS set research priorities based on lived experience. The goal is to guide research toward practical, symptom-level care strategies that reflect real-world needs.
đź”— Learn more about the PRADA project and explore the community-prioritized research questions: https://www.iconquerms.org/prada-project