03/30/2026
https://www.facebook.com/share/p/1B6ntTAEQJ/
๐๐ก๐จ๐ญ๐จ๐๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐๐ญ๐ข๐จ๐ง ๐ญ๐ก๐๐ซ๐๐ฉ๐ฒ ๐๐จ๐ซ ๐จ๐ฌ๐ญ๐๐จ๐๐ซ๐ญ๐ก๐ซ๐ข๐ญ๐ข๐ฌ: ๐๐๐๐ก๐๐ง๐ข๐ฌ๐ฆ๐ฌ ๐จ๐ ๐๐๐ญ๐ข๐จ๐ง
Fรกbio Pericinoto Giolo, et al
Photobiomodulation (PBM) is a non-invasive therapeutic modality with demonstrated effects in many fields related to regenerative medicine. In the field of orthopedics, in particular, PBM at various wavelengths has demonstrated the capacity to trigger multiple biological effects associated with protective mechanisms in musculoskeletal tissues. The articles cited in this review show that devices operating close to or within the near infrared range at low intensities can provoke responses which favor the shift in the predominant catabolic microenvironment typically seen in degenerative joint diseases, especially osteoarthritis (OA). These responses include proliferation, differentiation and expression of proteins associated with stable cell cycles. Additionally, PBM can also modulate oxidative stress, inflammation and pain by exerting regulatory effects on immune cells and blocking the transmission of pain through sensory neuron fibers, without adverse events. Collectively, these effects are essential in order to control the progression of OA, which is in part attributed to exacerbated inflammation and degradative enzymatic reactions which gradually contribute to the destruction of joint tissues. PBM may offer medical experts ease of application, financial viability, efficacy and lack of serious adverse events. Therefore, it may prove to be a suitable ally in the management of mild to moderate degrees of OA. This review explores and discusses the principal biological mechanisms of PBM and how the produced effects may contribute to the amelioration of osteoarthritic progression. [...]
https://www.wjgnet.com/2220-6132/full/v10/i3/29.htm