Hyde Drug Store

Hyde Drug Store Your local, family owned & operated pharmacy with Pharmacy Compounding available to all PA residents. We offer products and services beyond your pharmacy needs.

We have a full line of home healthcare items and equipment regularly available, including wheelchairs and walkers, respiratory supplies, support stockings and more. Our Compounding department specially formulates medicine for your individual needs, including your pet! Check out our website for additional services offered, including vaccine administration. Fun Fact: Hyde Drug Store is the oldest, continuously operating pharmacy in Lawrence County!

🥧 Our Holiday Hours This Week 🥧Here’s a quick look at when we’ll be open for those planning a visit before the holiday! ...
11/23/2025

🥧 Our Holiday Hours This Week 🥧

Here’s a quick look at when we’ll be open for those planning a visit before the holiday! ☺️




🏪 Today, George and Spero deserve a little extra recognition for National Entrepreneur Day.George took on Hyde Drug year...
11/18/2025

🏪 Today, George and Spero deserve a little extra recognition for National Entrepreneur Day.

George took on Hyde Drug years ago and has kept this family-owned pharmacy going!

Now working alongside his son, Spero, continuing the Hyde Drug tradition together!


Have you ever thought...💬 "Wait...why does my prescription look different this month?” 👀You’re not alone!  This is one o...
11/08/2025

Have you ever thought...💬

"Wait...why does my prescription look different this month?” 👀

You’re not alone! This is one of the most common questions we get.

Sometimes, when your medication looks a little different (shape, color, or size), it’s because we received the same medication from a different manufacturer.

💊 The active ingredient, dosage, and effectiveness are exactly the same. It just looks a bit different on the outside.

If you ever have a question about your prescription, please ask us!




11/06/2025

Today’s the day!

Michelle from Bost Benefits is here in-store to help with Medicare enrollment.

Come see her while she’s here... she’s happy to answer all your questions!




Well...it looks like everyone’s coming to Hyde Drug! 😀😅Whether it's for the great finds, the good vibes or our friendly ...
11/04/2025

Well...it looks like everyone’s coming to Hyde Drug! 😀😅

Whether it's for the great finds, the good vibes or our friendly Hyde Drug crew, come on in!

Everyone's always invited.









Address

2412 Wilmington Road
New Castle, PA
16105

Opening Hours

Monday 8am - 7pm
Tuesday 8am - 7pm
Wednesday 8am - 7pm
Thursday 8am - 7pm
Friday 8am - 7pm
Saturday 9am - 4pm

Telephone

+17246521451

Alerts

Be the first to know and let us send you an email when Hyde Drug Store posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to Hyde Drug Store:

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram

Hyde Drug Store | For all of your healthcare needs

Hyde Drug Store was founded by Alfred Hyde in 1890. Mr. Hyde operated the pharmacy and transitioned ownership to his son, Alfred, who operated the pharmacy until the mid 1950’s.

The Hydes began a tradition of personal service for their patients that has been continued through 2 more sets of owners until the pharmacy was purchased by Pharmacist George Stefanis, graduate of the University of Pittsburgh School of Pharmacy, in 1978. George has maintained the level of personal service created by the Hydes, and by utilizing the modern technology available to pharmacies today, Hyde Drug Store has taken personal service to a new level. This type of pharmacy practice is not something you find at the large corporate pharmacies that everyone is familiar with.

George’s son, Spero Stefanis Pharm. D. joined the practice officially in 2012, although he spent the previous 8 years working at the pharmacy while attending high school and college. Spero has brought with him all the knowledge of a recent graduate of Duquesne University School of Pharmacy and the technological skills available to best deliver up to date patient care.

The Hyde Drug Store team is easily accessible. We are open 7 days a week and when you call us, a person answers the phone. George and Spero plan to continue practicing pharmacy at Hyde Drug Store, attending to their patients’ needs for many years to come. Hyde Drug Store is the oldest, continuously operating pharmacy in the state of Pennsylvania and we plan to see that Hyde Drug Store continues these traditions.