11/25/2025
The role progesterone plays in healthy fertility and pregnancy has been known for quite some time.
But the link between progesterone and its action within the fallopian tube has remained less clear.
A recent animal study by McGlade, et al. revealed the important role progesterone signaling within the fallopian tube plays in supporting embryo development prior to implantation.
Specifically, the authors found an imbalance in progesterone signaling within the fallopian tube was linked to heightened inflammation and immune dysregulation, which negatively impacted preimplantation development.
This study provides additional insight into the unique role progesterone plays within the fallopian tube and the impact this hormone has during the earliest stages of development.
Your “True Health Matters!”
Stephen J. Hilgers, MD