11/13/2025
Psychopharmacology fast fact by Dr. Kehinde Elisha. 99.9% pass rate. www.npcertificationacademy.com
Rapid Fire Round 1 — Antidepressants
Q1: Which SSRI is most activating?
➡️ Fluoxetine (Prozac)
Q2: Which SSRI has the shortest half-life and highest withdrawal risk?
➡️ Paroxetine (Paxil)
Q3: Which SNRI is also FDA-approved for neuropathic pain?
➡️ Duloxetine (Cymbalta)
Q4: Which antidepressant causes weight loss and is contraindicated in seizure disorder?
➡️ Bupropion (Wellbutrin)
Q5: Which antidepressant increases appetite and causes sedation?
➡️ Mirtazapine (Remeron)
⚡ Rapid Fire Round 2 — Mood Stabilizers
Q6: What is the therapeutic serum range for lithium?
➡️ 0.6–1.2 mEq/L
Q7: What lab must be checked before starting lithium?
➡️ BUN/Creatinine, TSH, electrolytes, pregnancy test (in women)
Q8: Major risk of valproate (Depakote)?
➡️ Hepatotoxicity, pancreatitis, teratogenicity (neural tube defects)
Q9: Which mood stabilizer causes rash risk, including SJS?
➡️ Lamotrigine (Lamictal)
Q10: What is the drug interaction between lamotrigine and valproate?
➡️ Valproate increases lamotrigine levels — risk of rash; start lamotrigine at half dose.
🩸 Rapid Fire Round 3 — Antipsychotics
Q11: Which antipsychotic causes agranulocytosis?
➡️ Clozapine (Clozaril)
Q12: Which atypical antipsychotic has the highest metabolic risk?
➡️ Olanzapine (Zyprexa)
Q13: Which antipsychotic is least likely to cause weight gain?
➡️ Ziprasidone (Geodon) or Aripiprazole (Abilify)
Q14: What is the first-line treatment for acute dystonia?
➡️ Benztropine (Cogentin) or diphenhydramine (Benadryl)
Q15: What symptom differentiates NMS from serotonin syndrome?
➡️ Lead-pipe rigidity and elevated CPK (NMS)
😰 Rapid Fire Round 4 — Anxiolytics
Q16: Which benzodiazepine is safest in liver impairment?
➡️ Lorazepam (Ativan), Oxazepam, Temazepam (LOT)
Q17: Which medication treats GAD but is non-sedating and non-addictive?
➡️ Buspirone (Buspar)
Q18: Which SSRI is FDA-approved for panic disorder and OCD?
➡️ Sertraline (Zoloft)
🚀 Rapid Fire Round 5 — Stimulants & ADHD
Q19: Which stimulant has the highest abuse potential?
➡️ Short-acting amphetamines (Adderall IR)
Q20: What non-stimulant ADHD med is also used for anxiety or tics?
➡️ Guanfacine (Intuniv) or Clonidine (Kapvay)
Q21: What black box warning exists for atomoxetine (Strattera)?
➡️ Suicidal ideation in children/adolescents
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