06/21/2022
FOOD REACTIONS
đFood allergy involves IgE immune responses to food immediately after eating. Symptoms can be severe or mild like runny nose, hives, rash, abdominal pain, lip/ throat swelling, trouble breathing
đFood intolerance is a non-immune reaction to foods like dairy, histamines, sulfites and alcohol occurring due to a deficiency in enzymes/ nutrients needed to break it down. Symptoms may include inflammation, GI issues, cold and flu, flushing etc.
đFood sensitivity involves IgG or IgA immune reactivity and is typically driven by leaky gut and microbiome imbalances. Common foods are gluten, dairy, eggs, shellfish and tree nuts. There are hundreds of possible symptoms like sleep and mood changes, skin rash, migraines, joint pain, bloating, IBS, bladder issues and even heart palpitations.
TESTING
IgE-Reactivity can come from any food so itâs important to do a large blood panel. Your doctor can order this however functional testing may be deeper. My Vibrant panel includes about 100 foods.
IgG reactivity can be broken down into 4 sub-classes, 3 of which activate the complement system. The half-life of IgG subclass 1 (most prevalent) is 23 days so itâs recommended to follow an elimination diet for AT LEAST 3 weeks. This type of blood test is often run by functional medicine providers.
IgG 4 is unique in that itâs considered part of the Th2 immune system. While itâs involved with establishing tolerance to food, it can also drive autoimmune reactivity.
IgA protects the mucosal membranes including the GI tract, mouth, nose, lungs, bladder and is normally tested in blood with IgG. Itâs especially sensitive to gluten.
MRT-mediator Release testing and ALCAT-Antigen leucocyte antibody testing . These are similar and measure changes in size and qnty of leucocytes when exposed to a particular food.
PEPTIDES-IgG/IgA may miss food reactions by measuring whole protein molecules. For some, reactivity occurs later during digestion once individual peptides are liberated. Cyrex and vibrant zoomers are examples of peptides tests. I run gluten peptides on most clients.
These are all useful in different situations so work with someone to help you choose