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We’re an NYU Langone research team studying ketamine use—medical, recreational & in between. Help us explore its role. 🧠

09/24/2025

🚨 Poppers exposures are on the rise across the U.S.
Between 2013–2023, poison centers reported 2,431 cases:
• 1,110 (45.7%) inhalation exposures
• 1,367 (56.2%) ingestion exposures

📊 Both routes increased over time: � 💨 Inhalation: 52 cases → 228 cases � 🥤 Ingestion: 78 cases → 277 cases

⚠️ Ingestion was linked to a much higher rate of severe outcomes:
- Inhalation: 3.8% → 6.1% (not significant)
- Ingestion: 2.6% → 13.7% (significant rise)

High doses, especially from ingestion, can cause life-threatening complications like m**hemoglobinemia.

The study co-authored by Dr. Joseph J Palamar highlights the urgent need for prevention and harm reduction.

🗨️ Join the conversation, drop your thoughts below!
📖 Full research: link in bio.

**hemoglobinemia

📑 - Kerester S, Bloom J, Schwartz L, Mercurio-Zappala M, Palamar JJ, Su MK. Alkyl Nitrite (“Poppers”) Exposures in the US. JAMA Network Open. 2025

09/04/2025

❓ Why is ingesting poppers more dangerous than inhaling them?

📊 Data from U.S. poison centers (2013–2023) show a clear difference in severity:

Inhalation severe outcomes: 3.8% → 6.1%
Ingestion severe outcomes: 2.6% → 13.7%

⚠️ Ingestion, particularly in high doses, can cause life-threatening complications such as m**hemoglobinemia, when the blood can’t carry oxygen effectively.

The study co-authored by Dr. Joseph J Palamar, highlight the urgent need for prevention and harm reduction efforts to protect public health.

🗨️ Join the conversation, drop your thoughts below! Make sure to like and follow us for more.
📖 Full research: link in bio.

📑- Kerester S, Bloom J, Schwartz L, Mercurio-Zappala M, Palamar JJ, Su MK. Alkyl Nitrite (“Poppers”) Exposures in the US. JAMA Network Open. 2025

09/01/2025

💜 Today we come together for International Overdose Awareness Day (IOAD), the world’s largest annual campaign to end overdose.

This year’s theme, “One Big Family, Driven by Hope,” reminds us that while grief is real, action and hope connect us all.

🚨 What is an overdose?�It happens when the body is overwhelmed by a toxic amount of a substance. Signs may include difficulty breathing, blue lips or fingers, confusion, or unconsciousness.

📊 Fast facts:
- Opioids account for nearly 70% of overdose deaths worldwide.
- Between 2016–2024, Canada reported more than 49,000 overdose deaths.

Naloxone is a life-saving medication that can reverse opioid overdoses.

Together, we can reduce stigma, save lives, and bring hope to families and communities. 💜

Find more info and resources here: https://www.overdoseday.com

08/13/2025

🧪 “If I didn’t take fentanyl... how did it end up in my system?”

In the 2024 study Exposures to synthetic cathinones, fentanyl, and xylazine among nightclub attendees in New York City by Palamar, Abukahok, Acosta, Walton, Stang & Krotulski, 93.3% of fentanyl detections were unreported, indicating likely unintentional exposure.

That’s not all, more than half of synthetic cathinone exposures also went unreported.

This is why harm reduction efforts matter. Even if you think you know what you're taking, you may be exposed to substances like fentanyl without knowing.

📢 Spread awareness. Stay informed. Use tools like drug checking and peer education.

Make sure to like, comment your thoughts, share our posts and follow for more! 💬📲

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📑 - Palamar, Joseph J et al. “Exposures to Synthetic Cathinones, Fentanyl, and Xylazine among Nightclub Attendees in New York City, 2024.” Drug and alcohol dependence. 275 (2025): n. pag. Web.

07/30/2025

What’s being called “pink c*caine” isn’t a single drug at all. It’s often a mixture of several substances, including ketamine, M**A, and sometimes fentanyl. 🧪

As Dr. Joseph Palamar explains in Vanity Fair, this makes it unpredictable and potentially more dangerous than people realize. ⚠️

Understanding what’s behind the name can help reduce harm and encourage informed decision-making.

🔗 Read the full article via the link in bio
📲 Like, comment, and follow us for more!

***ne **a

07/25/2025

NYC nightlife is evolving, and so is what we’re detecting in clubgoers' systems.

In a recent study using saliva testing, 1 in 3 participants tested positive for THC, but that wasn’t all. 11.7% had THCA-A (a non-psychoactive THC precursor), and 8.9% had CBN, a semi-degraded cannabinoid.

Most participants had no idea they consumed anything beyond THC, which is exactly why this data matters. Saliva testing reveals what self-report can’t. Read between the lines—it’s not just about who’s using, but what they’re using.

💬 Share your thoughts and opinions in the comments.
📲 Follow us on all social medias for insights on ketamine and the latest in health research and public studies.

📖 🔗 Click the link in our bio for more information and full study details.

Satybaldiyeva, N., Yang, K. H., Krotulski, A. J., Walton, S. E., Stang, B., & Palamar, J. J. (2025). Saliva detection of the cannabinoids tetrahydrocannabinolic acid A (THCA-A) and cannabinol (CBN) among nightclub attendees in New York City, 2024. The American Journal of Drug and Alcohol Abuse.

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07/23/2025

Whether you’ve heard it called Tusi, Tuci, or Tusibi — it’s all part of the same trend.

This so-called “pink co***ne” has no consistent formula. Dr. Joseph Palamar points out in Vanity Fair that what’s being marketed under these names is often a mixture of substances, with no way to know what you’re getting. 👀

It may look familiar or trendy — but its unpredictability makes it risky.

🔗 Learn more in the article linked in our bio & follow us for more!

07/17/2025

What do you really know about what’s being consumed in NYC nightlife? 🕺

A 2024 study coauthored by Dr. Joseph Palamar collected saliva samples from over 1,000 NYC nightclub attendees. The results? Many tested positive for lesser-known cannabinoids like THCA-A and CBN, often without realizing it. 🍃

This carousel breaks down the full picture: detection rates, demographics, and why biological data is essential for understanding today’s cannabinoid trends.

These aren’t just small findings. They challenge how we monitor cannabis use through self-report and hint at the growing role of h**p-derived compounds post-2018 Farm Bill.

Want to know what’s really in your system after a night out? Let’s talk in the comments. 💬
🔗 Click the link in our bio for more information and full study details.
📲 Follow us on all socials for insights on ketamine, substance use, and the latest in health research and public studies.

📚 : Satybaldiyeva, N., Yang, K. H., Krotulski, A. J., Walton, S. E., Stang, B., & Palamar, J. J. (2025). Saliva detection of the cannabinoids tetrahydrocannabinolic acid A (THCA-A) and cannabinol (CBN) among nightclub attendees in New York City, 2024. The American Journal of Drug and Alcohol Abuse.

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07/08/2025

Don’t let the color fool you.

“Pink co***ne” sounds playful — but the truth is anything but. Known as Tusi or tusibi, this rising party drug has caught fire in pop culture and celebrity circles, but the science paints a much darker picture.

As NYU researcher and associate professor, Dr. Joseph Palamar told Vanity Fair,

“It’s not a drug, it’s a drug concoction… Pink co***ne can contain co***ne, but it’s almost always a mixture of ketamine and other drugs.”

What other drugs? Anything from M**A and caffeine to fentanyl or m**h. The pink color is often just marketing — not a signal of safety. This inconsistency can create wildly unpredictable effects, especially when mixed with alcohol or taken in larger doses.
Palamar adds:

“You could call anything Tusi… The Tusi phenomenon complicates the drug landscape because it has the potential to confuse both people who use and researchers alike.”

That means even experts can’t always be sure what’s inside — or how it will affect you.

📢 Spread the facts. Save a life.
💬 Comment to join the convo.
🔁 Repost to raise awareness.
🔗 Click the link here to read the full Vanity Fair article: https://www.vanityfair.com/style/story/tusi-pink-co***ne-drug

07/02/2025

How accurate is self-report when it comes to drug use? 🍃

Not very, according to a 2024 study of NYC clubgoers. Researchers found that many participants had cannabinoids like THCA-A and CBN in their saliva… even when they didn’t report using them. 👀

This highlights a key point: we need biological data to truly understand substance exposure in real-world settings.

The study, coauthored by Dr. Joseph Palamar and colleagues, shows how saliva testing can reshape our public health monitoring strategies. 📊

💬 What’s your opinion? Let’s talk in the comments.
📲 Follow us on all socials for insights on ketamine, substance use, and the latest in health research and public studies.
🔗 Click the link in our bio for more information and full study details.

📖: Satybaldiyeva, N., Yang, K. H., Krotulski, A. J., Walton, S. E., Stang, B., & Palamar, J. J. (2025). Saliva detection of the cannabinoids tetrahydrocannabinolic acid A (THCA-A) and cannabinol (CBN) among nightclub attendees in New York City, 2024. The American Journal of Drug and Alcohol Abuse.

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